Results 241 to 250 of about 86,596 (332)

The Participation of Malonyl Coenzyme A in the Biosynthesis of Mevalonic Acid

open access: hybrid, 1963
Jonathan D. Brodie   +2 more
openalex   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi   +2 more
wiley   +1 more source

Ultrasensitive protein-level detection for respiratory infectious viruses. [PDF]

open access: yesFront Immunol
Kobayashi Y   +5 more
europepmc   +1 more source

Effect of Nutraceutical Supplementation and Mediterranean Hypocaloric Diet on Calculated Steatosis Indices and Inflammation: Clinical and In Vitro Evidences

open access: yesMolecular Nutrition &Food Research, EarlyView.
This retrospective study evaluated the effects of nutraceutical supplementation (NS) and a Mediterranean hypocaloric diet (MHD) in NAFLD patients. Forty‐five overweight/obese subjects followed MHD with or without NS. After 3 months, only the MHD + NS group showed significant improvements in liver steatosis indices and inflammation.
Mariana Di Lorenzo   +11 more
wiley   +1 more source

Clinical guidelines highlight for the hospitalist: Management of cyclic vomiting syndrome in children

open access: yes
Journal of Hospital Medicine, EarlyView.
Yamileth N. Hernandez, Hannah M. Gardner
wiley   +1 more source

Continuous‐Wave (CW) Photo‐CIDNP NMR Spectroscopy: A Tutorial

open access: yesMagnetic Resonance in Chemistry, EarlyView.
ABSTRACT Photo‐chemically induced dynamic nuclear polarisation (photo‐CIDNP) is a nuclear spin‐selective magnetic resonance phenomenon that has traditionally been used to mechanistically study chemical reactions involving the (transient) formation of radical molecular species, extract EPR observables of short‐lived radicals, probe biomolecular ...
Lars T. Kuhn, Míriam Pérez‐Trujillo
wiley   +1 more source

Lactate‐mediated activation of GPR81 regulates BCR/Abl protein expression in chronic myeloid leukemia cells selected under low oxygen tension

open access: yesThe Journal of Pathology, EarlyView.
Abstract Chronic myeloid leukemia (CML) is a stem cell‐driven neoplasia characterized by the expression of the constitutively active tyrosine kinase (TK) BCR/Abl. Under low oxygen, a condition that characterizes stem cell niches (SCNs) in vivo, the oncogenic BCR/Ablprotein is suppressed.
Giulio Menegazzi   +5 more
wiley   +1 more source

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