Results 41 to 50 of about 46,349 (329)

Group B vitamins: prospective for multidisciplinary application: A review

open access: yesConsilium Medicum, 2023
Group B vitamins are used in various fields of medicine, most commonly in treating diseases of the peripheral and central nervous system, especially in treating pain. Group B vitamins are neurotropic agents; they play an essential role in the functioning
Liubov A. Kuzina, Gulnaz S. Kaishibaeva
doaj   +1 more source

The conversion of citrulline to arginine in kidney [PDF]

open access: yes, 1941
Glycocyamine is formed in the kidney by the transfer of the amidine group of arginine to the nitrogen atom of glycine. In the study of this reaction it was observed that glycocyamine was also formed from citrulline and glycine.
Borsook, Henry, Dubnoff, Jacob W.
core  

Isolation of an Enzyme-Coenzyme A Intermediate from Succinyl Coenzyme A-Acetoacetate Coenzyme A Transferase

open access: yesJournal of Biological Chemistry, 1967
Abstract An alkali-labile enzyme-coenzyme A intermediate has been isolated by molecular exclusion chromatography of succinyl-CoA-acetoacetate coenzyme A transferase after incubation with acetoacetyl-CoA or succinyl-CoA. Treatment of the intermediate with tritium-labeled sodium borohydride results in enzyme inactivation and incorporation of ...
L B, Hersh, W P, Jencks
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Cofactor Selectivity in Methylmalonyl Coenzyme A Mutase, a Model Cobamide-Dependent Enzyme. [PDF]

open access: yes, 2019
Cobamides, a uniquely diverse family of enzyme cofactors related to vitamin B12, are produced exclusively by bacteria and archaea but used in all domains of life.
Mok, Kenny   +5 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Binding of coenzymes to yeast alcohol dehydrogenase [PDF]

open access: yesJournal of the Serbian Chemical Society, 2010
In this work, the binding of coenzymes to yeast alcohol dehydrogenase (EC 1.1.1.1) were investigated. The main criterions were the change in the standard free energies for individual reaction steps, the internal equilibrium constants and the overall ...
VLADIMIR LESKOVAC   +4 more
doaj  

Ammonia assimilation in Bacillus polymyxa. 15N NMR and enzymatic studies [PDF]

open access: yes, 1987
Pathways of ammonia assimilation into glutamic acid and alanine in Bacillus polymyxa were investigated by 15N NMR spectroscopy in combination with measurements of the specific activities of glutamate dehydrogenase, glutamine synthetase, glutamate ...
Kanamori, Keiko   +2 more
core  

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

open access: yesFEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti   +8 more
wiley   +1 more source

Vitamin D3 affects liver expression of pro-/anti-inflammatory cytokines and nitric oxide synthases in type 2 diabetes

open access: yesExperimental Biology and Medicine
Our objective was to study the effect of vitamin D3 (VD) on hepatocellular oxidative-nitrosative stress and pro/anti-inflammatory cytokines in relation to nitric oxide (NO) formation and NO synthase (NOS) levels in type 2 diabetes mellitus (T2DM).
Ihor Shymanskyi   +9 more
doaj   +1 more source

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