Results 1 to 10 of about 262,210 (341)

COFACTOR: an accurate comparative algorithm for structure-based protein function annotation [PDF]

open access: goldNucleic Acids Res., 2012
We have developed a new COFACTOR webserver for automated structure-based protein function annotation. Starting from a structural model, given by either experimental determination or computational modeling, COFACTOR first identifies template proteins of ...
Ambrish Roy, Jianyi Yang, Yang Zhang
openalex   +2 more sources

Peroxisomal Cofactor Transport [PDF]

open access: yesBiomolecules, 2020
Peroxisomes are eukaryotic organelles that are essential for growth and development. They are highly metabolically active and house many biochemical reactions, including lipid metabolism and synthesis of signaling molecules.
Anastasija Plett   +2 more
doaj   +3 more sources

The methanogenic redox cofactor F420 is widely synthesized by aerobic soil bacteria [PDF]

open access: bronzeThe ISME Journal, 2016
Blair Ney   +12 more
openalex   +2 more sources

T cell subtype profiling measures exhaustion and predicts anti-PD-1 response

open access: yesScientific Reports, 2022
Anti-PD-1 therapy can provide long, durable benefit to a fraction of patients. The on-label PD-L1 test, however, does not accurately predict response.
Ian Schillebeeckx   +11 more
doaj   +1 more source

Biological Catalysis and Information Storage Have Relied on N-Glycosyl Derivatives of β-D-Ribofuranose since the Origins of Life

open access: yesBiomolecules, 2023
Most naturally occurring nucleotides and nucleosides are N-glycosyl derivatives of β-d-ribose. These N-ribosides are involved in most metabolic processes that occur in cells.
Katarzyna Wozniak, Krzysztof Brzezinski
doaj   +1 more source

Rossmann-toolbox: a deep learning-based protocol for the prediction and design of cofactor specificity in Rossmann fold proteins

open access: yesbioRxiv, 2021
The Rossmann fold enzymes are involved in essential biochemical pathways such as nucleotide and amino acid metabolism. Their functioning relies on interaction with cofactors, small nucleoside-based compounds specifically recognized by a conserved βαβ ...
K. Kamiński   +6 more
semanticscholar   +1 more source

Peroxisomal Metabolite and Cofactor Transport in Humans

open access: yesFrontiers in Cell and Developmental Biology, 2021
Peroxisomes are membrane-bound organelles involved in many metabolic pathways and essential for human health. They harbor a large number of enzymes involved in the different pathways, thus requiring transport of substrates, products and cofactors ...
Serhii Chornyi   +4 more
doaj   +1 more source

Hierarchically Porous Biocatalytic MOF Microreactor as a Versatile Platform towards Enhanced Multienzyme and Cofactor-Dependent Biocatalysis.

open access: yesAngewandte Chemie, 2020
Metal-organic frameworks (MOFs) have recently emerged as excellent hosting matrices for enzyme immobilization, offering superior physical and chemical protection for biocatalytic reactions.
Jieying Liang   +9 more
semanticscholar   +1 more source

The CoFactor database: organic cofactors in enzyme catalysis [PDF]

open access: yesBioinformatics, 2010
Abstract Motivation: Organic enzyme cofactors are involved in many enzyme reactions. Therefore, the analysis of cofactors is crucial to gain a better understanding of enzyme catalysis. To aid this, we have created the CoFactor database. Results: CoFactor provides a web interface to access hand-curated data extracted from ...
Fischer, Julia D.   +2 more
openaire   +2 more sources

Beyond NPK: Mineral Nutrient-Mediated Modulation in Orchestrating Flowering Time

open access: yesPlants, 2023
Flowering time in plants is a complex process regulated by environmental conditions such as photoperiod and temperature, as well as nutrient conditions.
Sang Eun Jun, Jae Sun Shim, Hee Jin Park
doaj   +1 more source

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