Results 231 to 240 of about 188,158 (291)

<i>De novo</i> synthesis of L-2-aminobutyric acid in <i>Escherichia coli</i> based on multi-layered metabolic engineering strategies. [PDF]

Synth Syst Biotechnol
Zhao Z, Liu Y, Zhu R, Yang F, Liu Z, You J, Pan X, Yang J, Rao Z.   +8 more
europepmc   +1 more source

The protease specificity of heparin cofactor II. Inhibition of thrombin generated during coagulation.

, 1985
K. A. Parker, Douglas M. Tollefsen
openalex   +1 more source

Spontaneous generation of diverse recombinant prion strains: sulfated glycan cofactors facilitate strain emergence but do not determine specific strain properties. [PDF]

Acta Neuropathol Commun
Lorenzo NL, Eraña H, Vidal E, Charco JM, Parga L, Díaz-Domínguez CM, Veiga S, Bravo S, Giler S, Geijo M, Requena JR, Castilla J.   +11 more
europepmc   +1 more source

CTx001 for Geographic Atrophy: A Gene Therapy Expressing Soluble, Truncated Complement Receptor 1 (Mini-CR1). [PDF]

Ophthalmol Sci
Rathi S, Didangelos A, Pisarenka S, Green R, Zafeiri S, Emery-Billcliff P, Patel N, Whalley P, Zamiri P, Tilakaratna V, Szula E, Hasan R, Munye MM, Unwin RD, Bishop PN, Keefe D, Clark SJ.   +16 more
europepmc   +1 more source

Engineering Fluoroacetate Dehalogenase by Growth‐Based Selections on Non‐Natural Organofluorides

Angewandte Chemie, EarlyView.
We present a high‐throughput selection system to engineer fluoroacetate dehalogenases (FAcDs). By challenging E. coli populations that produce diverse FAcD libraries to grow on non‐natural organofluorides as their sole carbon source, we isolated a panel of FAcD variants with improved activity and altered substrate specificity.
Suzanne C. Jansen, Pauline van Beers, Clemens Mayer   +2 more
wiley   +1 more source

An unusual Co-S bond links B₁₂ chaperones in an interprotein complex. [PDF]

Proc Natl Acad Sci U S A
Mascarenhas R, Ruetz M, Heitman N, Hall RL, Brunold TC, Banerjee R.   +5 more
europepmc   +1 more source

50 Years of Giese Reaction – a Personal View

Angewandte Chemie, EarlyView.
The Giese‐Reaction celebrates its 50. Birthday, it is a cyclic radical chain reaction centered around C,C‐bond formation in a three component synthesis. This minireview speaks about the birth of the name‐reaction, explains how the complete understanding of its reaction mechanism stimulates new methods in organic synthesis, and why it can proceed in ...
Martin Spichty, Hendrik Zipse, Salem Majouri, Katharina M. Fromm, Bernd Giese   +4 more
wiley   +1 more source

Unexpected Dual Function of Plant YUCCA Enzymes Links Chlorophyll Catabolism to Auxin Homeostasis

Angewandte Chemie, EarlyView.
YUCCA enzymes are well known to catalyze the main step of auxin biosynthesis in plants. Here, a hitherto undescribed dual function was discovered, revealing that some YUCCAs also act in chlorophyll degradation. In vitro feedback regulation furthermore suggests a link between chlorophyll degradation and hormone homeostasis and a physiological role of ...
Sina Rütschlin, Lei Zhang, Cornelia A. Karg, Michael Zwerger, Johanna M. Gostner, Simone Moser, Robin Teufel   +6 more
wiley   +1 more source

Novel Dual-Coenzyme Specificity and Thermostability of Malate Dehydrogenase Identified in the Cyanobacterium <i>Microcystis aeruginosa</i> PCC7806. [PDF]

Int J Mol Sci
Ge Y, Wu Y, Zhou B, Wu X, Ren Y, Zhu J, Ge Y.   +6 more
europepmc   +1 more source

Raman Spectroscopic Imaging Analysis of Signaling Proteins and Protein Cofactors in Living Cells

, 2018
Achut Prasad Silwal
openalex   +1 more source