AbstractThe function which maps a square matrix A to its cofactor matrix cof(A) is examined. A characterization is given for the image of the function. Its injective properties on the general linear group of nonsingular matrices are also addressed.
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Interaction of the oncoprotein transcription factor MYC with its chromatin cofactor WDR5 is essential for tumor maintenance. [PDF]
The oncoprotein transcription factor MYC is overexpressed in the majority of cancers. Key to its oncogenic activity is the ability of MYC to regulate gene expression patterns that drive and maintain the malignant state. MYC is also considered a validated
Adams, Clare M.+9 more
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Enzymatic regeneration of adenosine triphosphate cofactor [PDF]
Regenerating adenosine triphosphate (ATP) from adenosine diphosphate (ADP) by enzymatic process which utilizes carbamyl phosphate as phosphoryl donor is technique used to regenerate expensive cofactors.
Marshall, D. L.
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Regulators of complement activity mediate inhibitory mechanisms through a common C3bābinding mode [PDF]
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Atkinson, John P+14 more
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Cofactor Fingerprinting with STD NMR to Characterize Proteins of Unknown Function: Identification of a Rare cCMP Cofactor Preference [PDF]
Proteomics efforts have created a need for better strategies to functionally categorize newly discovered proteins. To this end, we have employed saturation transfer difference NMR with pools of closely related cofactors, to determine cofactor preferences.
Sem, Daniel, Yao, Huili
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Nitrogenase: A nucleotide-dependent molecular switch [PDF]
In the simplest terms, the biological nitrogen cycle is the reduction of atmospheric dinitrogen (N2) to ammonia with the subsequent reoxidation ammonia to dinitrogen (1).
Howard, James B., Rees, Douglas C.
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Rethinking NPN Classification from Face and Point Characteristics of Boolean Functions [PDF]
NPN classification is an essential problem in the design and verification of digital circuits. Most existing works explored variable symmetries and cofactor signatures to develop their classification methods. However, cofactor signatures only consider the face characteristics of Boolean functions.
arxiv
Biology of the molybdenum cofactor [PDF]
The transition element molybdenum (Mo) is an essential micronutrient for plants where it is needed as a catalytically active metal during enzyme catalysis. Four plant enzymes depend on molybdenum: nitrate reductase, sulphite oxidase, xanthine dehydrogenase, and aldehyde oxidase.
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Molecular Mechanism for Nitrogen fixation: first steps [PDF]
N2 association to the FeMo-cofactor of nitrogenase, including the recently identified central N ligand, has been investigated using first-principles electronic structure calculations. The oxidation state of the resting state of the cofactor and its electronic structure has been identified.
arxiv
Regularizing Matrix Factorization with User and Item Embeddings for Recommendation
Following recent successes in exploiting both latent factor and word embedding models in recommendation, we propose a novel Regularized Multi-Embedding (RME) based recommendation model that simultaneously encapsulates the following ideas via ...
Lee, Dongwon+3 more
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