Results 51 to 60 of about 308,164 (234)

Regularizing Matrix Factorization with User and Item Embeddings for Recommendation

open access: yes, 2018
Following recent successes in exploiting both latent factor and word embedding models in recommendation, we propose a novel Regularized Multi-Embedding (RME) based recommendation model that simultaneously encapsulates the following ideas via ...
Lee, Dongwon   +3 more
core   +1 more source

Harnessing Synergistic Cooperation of Neighboring Active Motifs in Heterogeneous Catalysts for Enhanced Catalytic Performance

open access: yesAdvanced Materials, EarlyView.
This review examines the critical role of neighboring active motifs in heterogeneous catalysts, emphasizing how their synergistic cooperativity can be rationally designed to modulate catalytic properties. The discussion centers on the modulation of electronic and geometric structures, categorizing the catalytic systems into metal‐acid (Brønsted/Lewis ...
Peng Yuan   +2 more
wiley   +1 more source

Separable Hamiltonian equations on Riemann manifolds and related integrable hydrodynamic systems

open access: yes, 2002
A systematic construction of St\"{a}ckel systems in separated coordinates and its relation to bi-Hamiltonian formalism are considered. A general form of related hydrodynamic systems, integrable by the Hamilton-Jacobi method, is derived.
Antonowicz   +27 more
core   +1 more source

Atomic Scale Engineering of Multivalence‐State Palladium Photocatalyst for Transfer Hydrogenation with Water as a Proton Source

open access: yesAdvanced Materials, EarlyView.
Photocatalytic transfer hydrogenation is achieved over a multivalence‐state palladium photocatalyst, in which protons generated from photocatalytic water splitting are added to unsaturated double bonds. The operando light‐induced Electron Paramagnetic Resonance (EPR) spectroscopy confirms the synergistic action between Pd single atoms and nanoparticles,
En Zhao   +12 more
wiley   +1 more source

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

open access: yesAdvanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania   +2 more
wiley   +1 more source

Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury

open access: yesAdvanced Materials Interfaces, EarlyView.
This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui   +5 more
wiley   +1 more source

Development of Photo‐Biocatalytic Redox System for Asymmetric Synthesis of Optically Active Amines Using Blue Light and Transaminases. A Case Study Toward Mavacamten

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Abstract α‐Chiral amines are versatile building blocks for the asymmetric synthesis of optically pure high‐added‐value chemicals, including pharmaceuticals, agrochemicals, and natural products. Herein, we report a one‐pot, two‐step sequential deracemization of racemic sec‐alcohols to optically enriched primary amines throught a photo‐biocatalytic ...
Natalia Antos   +5 more
wiley   +1 more source

Single‐Layer Radially Compartmentalized Paper Chip (RCP‐Chip) for Rapid Isothermal Multiplex Detection of SARS‐CoV‐2 Gene Targets

open access: yesAdvanced Sensor Research, EarlyView.
The single‐layer RCP‐Chip enables rapid, multiplexed detection of SARS‐CoV‐2 RNA using RT‐LAMP and gold nanoparticle‐enhanced colorimetric readouts. After sample loading, amplification occurs within radially arranged chambers, allowing simultaneous detection of E and N genes.
Pavithra Sukumar   +3 more
wiley   +1 more source

Insights into the Dynamics and Binding Mechanisms of the Alkhumra Virus NS2B/NS3 Protease: A Molecular Dynamics Study

open access: yesAdvanced Theory and Simulations, EarlyView.
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak   +2 more
wiley   +1 more source

A role for cofactor-cofactor and cofactor-histone interactions in targeting p300, SWI/SNF and Mediator for transcription

open access: yesThe EMBO Journal, 2003
Transcriptional activation from chromatin by nuclear receptors (NRs) requires multiple cofactors including CBP/p300, SWI/SNF and Mediator. How NRs recruit these multiple cofactors is not clear. Here we show that activation by androgen receptor and thyroid hormone receptor is associated with the promoter targeting of SRC family members, p300, SWI/SNF ...
Philip A. Cole   +4 more
openaire   +4 more sources

Home - About - Disclaimer - Privacy