Results 71 to 80 of about 221,534 (298)
Schematic of The Cofactor selection model of neurotropism.
, 2020 Left: A single input prion strain (yellow circle) preferentially uses a certain cofactor molecule (yellow ring). When replicating in an environment that contains multiple other potential cofactor molecules (red square and green triangle), the input prion
Nathan R. Deleault (2300191) +7 more
core +1 more source
Inhibition of chymotrypsin by heparin cofactor II. [PDF]
, 1985 Human heparin cofactor II is a plasma protein that is known to inhibit thrombin. The rate of thrombin inhibition by heparin cofactor II is accelerated (greater than or equal to 1000-fold) in the presence of the glycosaminoglycans, heparin and dermatan ...
Church, F. C. +2 more
core +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Chapter 10: Tetrahydrobiopterin: An Essential Cofactor of Nitric Oxide Synthase with an Elusive Role
, 2000 This chapter surveys the roles of pterins in biology and provides an understanding of biochemical pathways that determine tetrahydrobiopterin (BH4) levels in mammalian cells and how they are regulated.
Smith, C.L.
core +3 more sources
OPTIMIZATION OF ENZYME PARAMETERS FOR FERMENTATIVE PRODUCTION OF BIORENEWABLE FUELS AND CHEMICALS
Computational and Structural Biotechnology Journal, 2012 Microbial biocatalysts such as Escherichia coli and Saccharomyces cerevisiae have been extensively subjected to Metabolic Engineering for the fermentative production of biorenewable fuels and chemicals. This often entails the introduction of new enzymes,
Laura R. Jarboe +3 more
doaj +1 more source
Science, 2020 Crystal structure of an anti-obesity drug target reveals an important calcium-binding ...
Madhu, Chaturvedi, Arun K, Shukla
openaire +3 more sources
Backbone dynamics of complement control protein (CCP) modules reveals mobility in binding surfaces [PDF]
, 2004 The regulators of complement activation (RCA) are critical to health and disease because their role is to ensure that a complement-mediated immune response to infection is proportionate and targeted.
Krystyna Bromek +19 more
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
APOBEC-1 cofactors regulate APOBEC3-induced mutations in hepatitis B virus
Journal of VirologyAPOBEC3 proteins (A3s) play an important role in host innate immunity against viruses and DNA mutations in cancer. A3s-induced mutations in both viral and human DNA genomes vary significantly from non-lethal mutations in viruses to localized ...
Zhigang Chen +5 more
doaj +1 more source
Teorema Pohon Matriks Untuk Menentukan Banyaknya Pohon Rentangan Graf Bipartisi Komplit (Km,n)
Fokus, 2016 This research aims to observes panning tree number of complete bipartite graph (Km,n) by matrix-tree theorem.This research was using library research method which the step are:(1)Drawing complete bipartite graph (Km,n) where m= 1,2,3,4,and; (2)Determinin
Novia Rahmawati
doaj +1 more source