Results 81 to 90 of about 2,155 (232)
Annals of Medicine, 2021 Introduction Strategies to address the problem of poorly water-soluble drugs encompass the conversion of a crystalline drug into an amorphous form to promote its apparent solubility and dissolution.
Ana C. Bastos +3 more
doaj +1 more source
Beyond Cocrystals: Hierarchical Functional Assemblies via Noncovalent Synthesis
Advanced Science, Volume 13, Issue 13, 3 March 2026.Non‐covalent interactions (NCIs) drive the formation of organic cocrystals with diverse structures and tunable optoelectronic properties. This review explores the essential factors governing these properties, highlighting how the sequential nucleation of cocrystals leads to the self‐assembly of organic hierarchical structures (OHSs).
Ya‐Nan Zhu +6 more
wiley +1 more source
Single-crystal X-ray diffraction and NMR crystallography of a 1:1 cocrystal of dithianon and pyrimethanil [PDF]
, 2017 A single-crystal X-ray diffraction structure of a 1:1 cocrystal of two fungicides, namely dithianon (DI) and pyrimethanil (PM), is reported [systematic name: 5,10-dioxo-5H,10H-naphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile–4,6-dimethyl-N-phenyl ...
Brown, Steven P. +6 more
core +1 more source
Chirality, Volume 38, Issue 3, March 2026.(S)‐ibuprofen or ketoprofen were used to resolve mefloquine, forming double salts structurally similar to the racemic forms. ABSTRACT The formation of salts remains a highly sought‐after yet unpredictable strategy for resolving chiral drugs. Using a drug–drug approach, we have investigated the crystallization behavior of Mefloquine (Mf), a racemic ...
Juliana B. Martins +3 more
wiley +1 more source
Rational Coformer or Solvent Selection for Pharmaceutical Cocrystallization or Desolvation [PDF]
Journal of Pharmaceutical Sciences, 2012 It is demonstrated that the fluid-phase thermodynamics theory conductor-like screening model for real solvents (COSMO-RS) as implemented in the COSMOtherm software can be used for accurate and efficient screening of coformers for active pharmaceutical ingredient (API) cocrystallization.
Yuriy A, Abramov +2 more
openaire +2 more sources
Thermodynamic investigation of carbamazepine-saccharin co-crystal polymorphs [PDF]
, 2017 YesPolymorphism in active pharmaceutical ingredients (APIs) can be regarded as critical for the potential that crystal form can have on the quality, efficacy and safety of the final drug product.
Aitipamula +51 more
core +1 more source
Hittite Journal of Science and Engineering, 2019 Two co-crystals of p-aminobenzoic acid with isonicotinamide and pyrazine were prepared in acetone-ethanol solution by solvent evaporation method in the 1:1 cytochiometric ratio.
Fureya Elif Ozbek
doaj +1 more source
Crystal Engineering of Ionic Cocrystals Sustained by Azolium···Azole Heterosynthons
Pharmaceutics, 2022 Crystal engineering of multi-component molecular crystals, cocrystals, is a subject of growing interest, thanks in part to the potential utility of pharmaceutical cocrystals as drug substances with improved properties. Whereas molecular cocrystals (MCCs)
Maryam Rahmani +3 more
doaj +1 more source
Larvicidal Activity of Naringenin: Betaine Cocrystals Against Aedes Aegypti
Crystal Research and Technology, Volume 61, Issue 2, February 2026.This study demonstrates that naringenin: betaine cocrystals significantly enhance larvicidal activity against Aedes aegypti compared to physical mixtures or pure compounds. Improved dissolution properties contributed to higher mortality rates, supporting the use of cocrystallization as a promising green technology for vector management.
Felipe Zaniol +4 more
wiley +1 more source
A New Method for Producing Pharmaceutical Co-crystals: Laser Irradiation of Powder Blends [PDF]
, 2016 In this work, a high-power CO2 laser was used to irradiate powder blends of co-crystal formers, with the specific aim of trying to cause recrystallization to a co-crystal structure.
Basit, AW +2 more
core +1 more source