Results 71 to 80 of about 1,361 (189)

Exploiting Supramolecular Synthons in Cocrystals of Two Racetams with 4-Hydroxybenzoic Acid and 4-Hydroxybenzamide Coformers

open access: yesChemistry, 2023
Structures of three cocrystals of nootropic racetams were studied. They included two cocrystals of phenylpiracetam (PPA) with 4-hydroxybenzoic acid (HBA) with different stoichiometries, PPA·HBA and PPA·2HBA, and cocrystal of 2-(4-phenyl-2-oxopyrrolidin-1-
Jason Marquez   +6 more
doaj   +1 more source

Double Salts and Racemate in Mefloquine–Ibuprofen and Mefloquine–Ketoprofen Systems. A Structural and Thermochemical Analysis

open access: yesChirality, Volume 38, Issue 3, March 2026.
(S)‐ibuprofen or ketoprofen were used to resolve mefloquine, forming double salts structurally similar to the racemic forms. ABSTRACT The formation of salts remains a highly sought‐after yet unpredictable strategy for resolving chiral drugs. Using a drug–drug approach, we have investigated the crystallization behavior of Mefloquine (Mf), a racemic ...
Juliana B. Martins   +3 more
wiley   +1 more source

Properadic coformality of spheres

open access: yes
We define a properad $Y^{(n)}_\infty$ that encodes $n$-pre-Calabi--Yau algebras with vanishing copairing. These algebras include chains on the based loop space of any space $X$ endowed with a fundamental class $[X]$ such that $(X,[X])$ satisfies Poincaré duality of degree $n \geqslant 1$ with local system coefficients, such as an oriented manifold ...
Emprin, Coline, Takeda, Alex
openaire   +2 more sources

Single-Crystal Plasticity Defies Bulk-Phase Mechanics in Isoniazid Cocrystals with Analogous Coformers

open access: yes, 2019
The crystal structures of four INZ cocrystals with analogous crystal coformers were probed to understand the relationships among molecular packing, H-bonding dimensionality, single-crystal plasticity, and bulk mechanical behavior.
Chenguang Wang (27726)   +17 more
core   +1 more source

Larvicidal Activity of Naringenin: Betaine Cocrystals Against Aedes Aegypti

open access: yesCrystal Research and Technology, Volume 61, Issue 2, February 2026.
This study demonstrates that naringenin: betaine cocrystals significantly enhance larvicidal activity against Aedes aegypti compared to physical mixtures or pure compounds. Improved dissolution properties contributed to higher mortality rates, supporting the use of cocrystallization as a promising green technology for vector management.
Felipe Zaniol   +4 more
wiley   +1 more source

Systematic coformer contribution to cocrystal stabilization: energy and packing trends

open access: yesCrystEngComm, 2020
CSD data mining and energy calculations show that coformer self-interactions might significantly contribute to the packing energy stabilization of cocrystals.
Paolo P. Mazzeo   +4 more
openaire   +3 more sources

Cocrystals of Isoniazid with Polyphenols: Mechanochemical Synthesis and Molecular Structure

open access: yesCrystals, 2020
Isoniazid is used as anti-tuberculosis drug which possesses functional groups capable of forming hydrogen bonds. A series of cocrystals of isoniazid (INH) with polyphenolic coformers such as catechol (CAT), orcinol (ORC), 2-methylresorcinol (MER ...
Juan Saulo González-González   +6 more
doaj   +1 more source

Theoretical methods for the rational selection of coformers to form drug co-crystals

open access: yes, 2021
Kada je riječ o farmaceutskoj industriji, posljednjih nekoliko godina se kokristalima pridaje sve veća pažnja. Riječ je o višekomponentnim supramolekularnim oblicima koji se sastoje od nenabijene aktivne farmaceutske tvari i koformera, koji mogu biti ...
Jurić, Ivona
core   +1 more source

Bio-Purines as Co-Formers in Resveratrol Amorphous Systems

open access: yesCrystals
In the organic biomineralization of guanine (GUA), amorphous GUA is utilized to enhance its solubility, facilitating its transport for the formation of biominerals, and GUA nanocrystals are employed to protect tissues from ultraviolet damage.
Yuhang Liu   +4 more
doaj   +1 more source

Impact of Halogen Substituent Nature and Position on the Structural and Energetic Properties of Carbamazepine Cocrystals with Meta‐Halobenzoic Acids: A Two‐Pathway Synthesis Study

open access: yesChemPlusChem, Volume 90, Issue 11, November 10, 2025.
This study explores how halogen substitution in benzoic acid coformers affects the structure and stability of carbamazepine cocrystals. Isostructurality and enhanced lattice stability with heavier halogens are revealed, highlighting key supramolecular interactions.
Artur Mirocki, Mattia Lopresti
wiley   +1 more source

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