Results 71 to 80 of about 649 (170)

Preparation and Characterization of Carbamazepine Cocrystal in Polymer Solution

open access: yesPharmaceutics, 2017
In this study, we attempted to prepare carbamazepine (CBZ) cocrystal through the solution method in ethanol-water solvent mixture (volume ratio 1:1) and polyvinyl pyrrolidone (PVP) solution.
Hao Zhang   +4 more
doaj   +1 more source

Impact of Halogen Substituent Nature and Position on the Structural and Energetic Properties of Carbamazepine Cocrystals with Meta‐Halobenzoic Acids: A Two‐Pathway Synthesis Study

open access: yesChemPlusChem, Volume 90, Issue 11, November 10, 2025.
This study explores how halogen substitution in benzoic acid coformers affects the structure and stability of carbamazepine cocrystals. Isostructurality and enhanced lattice stability with heavier halogens are revealed, highlighting key supramolecular interactions.
Artur Mirocki, Mattia Lopresti
wiley   +1 more source

Formation of Prenylated Chalcone Xanthohumol Cocrystals: Single Crystal X-Ray Diffraction, Vibrational Spectroscopic Study Coupled with Multivariate Analysis

open access: yesMolecules, 2019
Four novel xanthohumol (XN) cocrystals with pharmaceutically acceptable coformers, such as nicotinamide (NIC), glutarimide (GA), acetamide (AC), and caffeine (CF) in the 1:1 stoichiometry were obtained by the slow evaporation solution growth technique ...
Iwona Budziak   +2 more
doaj   +1 more source

Origin of phase relative stability and phase transformation in an S‐ibuprofen–nicotinamide cocrystal

open access: yesActa Crystallographica Section C, Volume 81, Issue 11, Page 658-665, November 2025.
The crystal structure of the metastable form of S‐ibuprofen–nicotinamide cocrystals was solved from powder X‐ray diffraction data and explains the main mechanisms responsible for the relative stability of the two forms of the cocrystals. This also made it possible to explain the transition mechanism between the two forms with temperature.The crystal ...
Mathieu Guerain   +7 more
wiley   +1 more source

On the cohomology of elliptic coformal spaces

open access: yes, 2019
In this article, we pursue the study begun in \cite{Lup02} on the cohomology of rationally elliptic coformal spaces. Consequently, we complete, for such spaces, the proof of Lupton's conjecture and deduce Hilali's.
openaire   +2 more sources

Solid solution quantification from full powder X‐ray diffraction profile: novel application of multivariate calibration

open access: yesJournal of Applied Crystallography, Volume 58, Issue 5, Page 1700-1711, October 2025.
A new application of quantitative chemometric models (principal component regression and partial least‐squares regression) to powder X‐ray diffraction data is tested. The approach allows evaluation of the relative composition of solid solutions via the characteristic profile shift.
Laura Macchietti   +4 more
wiley   +1 more source

The curious case of proton migration under pressure in the malonic acid and 4,4′-bipyridine cocrystal

open access: yesIUCrJ
In the search for new active pharmaceutical ingredients, the precise control of the chemistry of cocrystals becomes essential. One crucial step within this chemistry is proton migration between cocrystal coformers to form a salt, usually anticipated by ...
Ewa Patyk-Kaźmierczak   +6 more
doaj   +1 more source

Design, characterization, and evaluation of an aceclofenac cocrystal for improved solubility and stability

open access: yesJournal of Applied Pharmaceutical Research
Background: Co-crystallization enhances APIs by forming noncovalent interactions with coformers, thereby improving physicochemical properties. Aceclofenac was selected for its low solubility, whereas L-lysine serves as a coformer to enhance solubility ...
Aditay Kumar, Mahesh Kumar
doaj   +1 more source

Piroxicam cocrystals with phenolic coformers: preparation, characterization, and dissolution properties

open access: yesPharmaceutical Development and Technology, 2018
This study explores the preparation and investigation of dissolution properties of piroxicam cocrystals. Differential scanning calorimetry (DSC) was used to determine the capability of resorcinol (RES), methylparaben (MPB), and vanillin (VAN) to form cocrystals with piroxicam (PRX). Generation of cocrystals was attempted by liquid assisted grinding and
Shahram, Emami   +3 more
openaire   +2 more sources

CoFormer: Collaborating With Heterogeneous Edge Devices for Scalable Transformer Inference

open access: yesIEEE Transactions on Computers
The impressive performance of transformer models has sparked the deployment of intelligent applications on resource-constrained edge devices. However, ensuring high-quality service for real-time edge systems is a significant challenge due to the considerable computational demands and resource requirements of these models.
Guanyu Xu   +7 more
openaire   +2 more sources

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