Results 61 to 70 of about 1,361 (189)
Mechanochemically Driven Synthesis of Anticancer Cocrystals: A Case Study of Lenalidomide
Chemistry–Methods, Volume 6, Issue 5, May 2026.The combination of crystal engineering and mechanochemical approaches is a powerful strategy for the rational screen and development of new solid forms of active pharmaceutical ingredients (API). New supramolecular patterns formed between an API and a coformer allow the adjustment of physicochemical properties of drugs.
Ana C. S. Carvalho +15 more
wiley +1 more source
Cocrystallization of phenanthroline and neocuproine with selected coformers
, 2018 Ziel dieser Arbeit war es, Kokristalle (Molekülverbindungen) der beiden Modell-substanzen o-Phenanthrolin und Neocuproin herzustellen und zu charakterisieren.
Achammer, Elisabeth
core +2 more sources
Acta Crystallographica Section E: Crystallographic Communications, 2021 Ionic co-crystals are co-crystals between organic molecules and inorganic salt coformers. Co-crystals of pharmaceuticals are of interest to help control polymorph formation and potentially improve stability and other physical properties.
Elizabeth Tinapple +2 more
doaj +1 more source
Solubilities of CL‐20 and MDNT in Organic Solvents for Technical Cocrystallization
Propellants, Explosives, Pyrotechnics, Volume 51, Issue 5, Page 761-768, May 2026.ABSTRACT The 1:1 molar cocrystal of 2,4,6,8,10,12‐hexanitro‐2,4,6,8,10,12‐hexaazaisowurtzitane (CL‐20) and 1‐methyl‐3,5‐dinitro‐1,2,4‐triazole (MDNT) is reported to show a detonation velocity 100 m/s faster than β‐HMX. To establish a scalable synthesis method, the solubility of ε‐CL‐20 and MDNT was investigated.
Eduard Wegert +2 more
wiley +1 more source
Hittite Journal of Science and Engineering, 2019 Two co-crystals of p-aminobenzoic acid with isonicotinamide and pyrazine were prepared in acetone-ethanol solution by solvent evaporation method in the 1:1 cytochiometric ratio.
Fureya Elif Ozbek
doaj +1 more source
Molecules, 2020 The halogen-bond (X-bond) donors 1,3- and 1,4-diiodotetrafluorobenzene (1,3-di-I-tFb and 1,4-di-I-tFb, respectively) form cocrystals with trans-1,2-bis(2-pyridyl)ethylene (2,2′-bpe) assembled by N···I X-bonds.
Jay Quentin +2 more
doaj +1 more source
Crystal Engineering of Ionic Cocrystals Sustained by Azolium···Azole Heterosynthons
Pharmaceutics, 2022 Crystal engineering of multi-component molecular crystals, cocrystals, is a subject of growing interest, thanks in part to the potential utility of pharmaceutical cocrystals as drug substances with improved properties. Whereas molecular cocrystals (MCCs)
Maryam Rahmani +3 more
doaj +1 more source
Charge Transport in Ternary Charge‐Transfer Solid Solution Single Crystals
Advanced Functional Materials, Volume 36, Issue 26, 30 March 2026.This study deconvolutes the roles of indirect (superexchange) and direct electronic coupling on charge transport in single crystals of an organic charge‐transfer molecular semiconductor (OSC). This model system elegantly demonstrates that structural defects introduced by chemical dopants play a significant role in the electronic performance ...
Jonathan C. Novak +7 more
wiley +1 more source
Beyond Cocrystals: Hierarchical Functional Assemblies via Noncovalent Synthesis
Advanced Science, Volume 13, Issue 13, 3 March 2026.Non‐covalent interactions (NCIs) drive the formation of organic cocrystals with diverse structures and tunable optoelectronic properties. This review explores the essential factors governing these properties, highlighting how the sequential nucleation of cocrystals leads to the self‐assembly of organic hierarchical structures (OHSs).
Ya‐Nan Zhu +6 more
wiley +1 more source
, 2023 Milrinone (MRN) is a second-generation bipyridine phosphodiesterase inhibitor that improves cardiac function and peripheral vasodilation in acute decongested heart failure patients.
Abhijit Garai +5 more
core +1 more source