Results 41 to 50 of about 454,445 (256)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Hypothesized drivers of the bias blind spot—cognitive sophistication, introspection bias, and conversational processes [PDF]

open access: yesJudgment and Decision Making, 2022
Individuals often assess themselves as being less susceptible to common biases compared to others. This bias blind spot (BBS) is thought to represent a metacognitive error.
David R. Mandel   +4 more
doaj  

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Cognitive biases as interrupters in evidence based practice decision-making

open access: yesJournal of the Medical Library Association
Objectives: To identify the most frequently-observed forms of cognitive bias among Health Information Professionals (HIPs) during decision-making processes.
Jonathan D. Eldredge, Deirdre A. Hill
doaj   +1 more source

Resilience and Cognitive Bias in Chinese Male Medical Freshmen

open access: yesFrontiers in Psychiatry, 2017
BackgroundPsychological resilience has become a hot issue in positive psychology research. However, little is known about cognitive bias difference of individuals with different resilience levels.
Li Peng, Hong-Wen Cao, Yongju Yu, Min Li
doaj   +1 more source

A pandemic of cognitive bias [PDF]

open access: yesIntensive Care Medicine, 2020
Francesco Landucci, Massimo Lamperti
openaire   +2 more sources

Cognitive Bias in Medico-legal Judgments

open access: yes, 2022
As humans, our perceptions and judgments are naturally colored by our beliefs, experiences, and desires. Consequently, two individuals with different mindsets or working in different contexts may interpret the same information in markedly different ways (i.e., cognitive bias), especially when that information is ambiguous.
Jeff Kukucka, Keith A. Findley
openaire   +2 more sources

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

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