Results 21 to 30 of about 332,380 (290)

T Cells Actively Infiltrate the White Matter of the Aging Monkey Brain in Relation to Increased Microglial Reactivity and Cognitive Decline

Frontiers in Immunology, 2021
Normal aging is characterized by declines in processing speed, learning, memory, and executive function even in the absence of neurodegenerative diseases such as Alzheimer's Disease (AD). In normal aging monkeys and humans, neuronal loss does not account
Katelyn V. Batterman, Payton E. Cabrera, Tara L. Moore, Tara L. Moore, Tara L. Moore, Douglas L. Rosene, Douglas L. Rosene   +6 more
doaj   +1 more source

Agents of change: establishing quality improvement collaboratives to improve adherence to Australian clinical guidelines for dementia care

Implementation Science, 2018
Background Dissemination of clinical practice guidelines alone is insufficient to create meaningful change in clinical practice. Quality improvement collaborative models have potential to address the evidence-practice gap in dementia care because they ...
Monica Cations, Maria Crotty, Janna Anneke Fitzgerald, Susan Kurrle, Ian D. Cameron, Craig Whitehead, Jane Thompson, Billingsley Kaambwa, Kate Hayes, Lenore de la Perrelle, Gorjana Radisic, Kate E. Laver   +11 more
doaj   +1 more source

Age-associated cognitive decline [PDF]

British Medical Bulletin, 2009
Age-associated cognitive decline-or normal (non-pathological, normative, usual) cognitive ageing-is an important human experience which differs in extent between individuals. The determinants of the differences in age-related cognitive decline are not fully understood.
Deary, I. J., Corley, J., Gow, A. J., Harris, Sarah, Houlihan, Lorna, Marioni, Riccardo E, Penke, L., Rafnsson, S. B., Starr, John   +8 more
openaire   +5 more sources

People living in nursing care facilities who are ambulant and fracture their hips: description of usual care and an alternative rehabilitation pathway

BMC Geriatrics, 2020
Background Little is known about treatment provided to people living in nursing care facilities (NCFs) after hospital admission for hip fracture. In addition, there are no clinical guidelines for rehabilitation and recovery following hip fracture for ...
Maggie Killington, Owen Davies, Maria Crotty, Rhiannon Crane, Naomi Pratt, Kylie Mills, Arabella McInnes, Susan Kurrle, Ian D. Cameron   +8 more
doaj   +1 more source

Cognition: The brain's decline [PDF]

Nature, 2012
Treating cognitive problems common in elderly people requires a deeper understanding of how a healthy brain ages.
openaire   +3 more sources

Increasing the uptake of vitamin D supplement use in Australian residential aged care facilities: results from the vitamin D implementation (ViDAus) study

BMC Geriatrics, 2020
Background Adequate (≥800 IU/day) vitamin D supplement use in Australian residential aged care facilities (RACFs) is variable and non-optimal. The vitamin D implementation (ViDAus) study aimed to employ a range of strategies to support the uptake of this
Pippy Walker, Annette Kifley, Susan Kurrle, Ian D. Cameron   +3 more
doaj   +1 more source

SImplification of Medications Prescribed to Long-tErm care Residents (SIMPLER): study protocol for a cluster randomised controlled trial

Trials, 2018
Background Complex medication regimens are highly prevalent in residential aged care facilities (RACFs). Strategies to reduce unnecessary complexity may be valuable because complex medication regimens can be burdensome for residents and are costly in ...
Janet K. Sluggett, Esa Y. H. Chen, Jenni Ilomäki, Megan Corlis, Sarah N. Hilmer, Jan Van Emden, Choon Ean Ooi, Kim-Huong Nguyen, Tracy Comans, Michelle Hogan, Tessa Caporale, Susan Edwards, Lyntara Quirke, Allan Patching, J. Simon Bell   +14 more
doaj   +1 more source

Steeper memory decline after COVID-19 lockdown measures

Alzheimer’s Research & Therapy, 2023
Background During COVID-19 lockdown measures, memory clinic patients reported worries for faster cognitive decline, due to loss of structure and feelings of loneliness and depression. We aimed to investigate the impact of the COVID-19 lockdown on rate of
Els D. Bakker, Stéphanie L. van der Pas, Marissa D. Zwan, Freek Gillissen, Femke H. Bouwman, Philip Scheltens, Wiesje M. van der Flier, Ingrid S. van Maurik   +7 more
doaj   +1 more source

Hypertension and cognitive decline [PDF]

British Journal of Psychiatry, 1999
Significant associations have been reported between cognitive decline, dementia and measures of cardiovascular and cerebrovascular disease. Such findings raise important possibilities for prevention of dementia through reducing the burden of vascular pathology.
openaire   +3 more sources

Psychotropic medications in older people in residential care facilities and associations with quality of life: a cross-sectional study

BMC Geriatrics, 2018
Background Psychotropic medications have been associated with many adverse outcomes in older people living in residential care. Home-like models of residential care may be preferable to traditional models of care and we hypothesized that this model may ...
Stephanie L. Harrison, Clare Bradley, Rachel Milte, Enwu Liu, Lisa Kouladjian O’Donnell, Sarah N. Hilmer, Maria Crotty   +6 more
doaj   +1 more source