Results 61 to 70 of about 1,931,867 (302)

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen, Mark Paine, Soohyun Lee, Amir Fazlollahi, Baibin (Ben) Wang, John D. O'Sullivan, Peter J. Nestor   +6 more
wiley   +1 more source

Unhealthy oral status contributes to the older patients with cognitive frailty: an analysis based on a 5-year database

BMC Geriatrics, 2022
Background Oral health is associated with the onset and deterioration of cognitive function and physical frailty, which can be improved with appropriate interventions.
Zhiqiong Jiang, Xintong Liu, Yang Lü
doaj   +1 more source

The Association of Physical Function With Psychosocial Patient‐Reported Outcomes in People With Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective To evaluate how modifiable psychosocial factors and fatigue relate to physical functioning in patients with systemic lupus erythematosus (SLE). Methods In this cross‐sectional study of two demographically distinct cohorts (Approaches to Positive, Patient‐Centered Experiences of Aging with Lupus [APPEAL] and California Lupus Epidemiology Study
Mrinalini Dey, Jessica Fitzpatrick, Maria Dall'Era, Charmayne Dunlop‐Thomas, Courtney Hoge, S. Sam Lim, Patricia P. Katz, Jinoos Yazdany, Laura C. Plantinga   +8 more
wiley   +1 more source

Deviations in Hippocampal Subregion Associated With Cognitive and Physical Frailty in Older Adults With Cognitive Frailty [PDF]

, 2020
Abstract Background The hippocampus is a complex, heterogeneous structure that is composed of widely different and interacting subregions. Atrophy of these subregions has been implicated in a variety of neurodegenerative diseases. Cognitive frailty is a kind of neurodegenerative disease with unclear neuropathological changes.
Mingyue Wan, Yu Ye, Huiying Lin, Ying Xu, Shengxiang Liang, Rui Xia, Jianquan He, Pingting Qiu, Chengwu Huang, Jing Tao, Lidian Chen, Guohua Zheng   +11 more
openaire   +1 more source

Prevalence and possible factors of cognitive frailty in the elderly with hypertension and diabetes

Frontiers in Cardiovascular Medicine, 2022
BackgroundCognitive frailty is the coexistence of physical frailty and mild cognitive impairment. Research shows that cognitive frailty is related to an increased risk of hospitalization, mortality, disability, and dementia. Diabetes and hypertension are
Shourong Lu, Qiao Xu, Jie Yu, Ying Yang, Zhuo Wang, Bingshan Zhang, Shuqiang Wang, Xiaorong Chen, Yunyun Zhang, Xiaowei Zhu, Kan Hong   +10 more
doaj   +1 more source

Associations between dehydration, cognitive impairment, and frailty in older hospitalized patients: an exploratory study [PDF]

, 2016
The current exploratory study (a) assessed the prevalence of dehydration in older adults (age ≤60 years) with and without cognitive impairment (CI) admitted to the hospital; and (b) examined associations between dehydration, CI, and frailty.
Eeles, Eamonn, Travers, Catherine, McCrow, Judy, Catherine Travers, Morton, Margaret, Margaret Morton, Judy McCrow, Eamonn Eeles, Harvey, Keren, Keren Harvey   +9 more
core   +1 more source

Frailty Predicts Incident Osteoporotic Fractures in Veterans with Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Rheumatoid arthritis (RA) is associated with an increased risk of frailty and osteoporosis, but the relationship between frailty and incident osteoporotic fractures in RA is underexplored. Methods Data were from the Veterans Affairs (VA) Rheumatoid Arthritis Registry. Frailty was measured using the VA Frailty Index (VAFI).
Katherine D. Wysham, Hannah F. Brubeck, Aaron Baraff, Punyasha Roul, Namrata Singh, James S. Andrews, Grant W. Cannon, Gary A. Kunkel, Ted R. Mikuls, Bryant R. England, Dolores M. Shoback, Patricia P. Katz, Jose M. Garcia, Ariela R. Orkaby, Joshua F. Baker   +14 more
wiley   +1 more source

A secondary analysis of cortical atrophy and plasma amyloid β patterns in older patients with cognitive frailty undergoing elective surgery

BMC Geriatrics
Background The etiology of cognitive impairment in frailty may be related to age or to an independent neurodegenerative process, such as Alzheimer’s disease (AD).
Rudolf Mörgeli, Friedrich Borchers, Insa Feinkohl, Sophie K. Piper, Tobias Pischon, Arjen J.C. Slooter, Claudia Spies, Janine Wiebach, Georg Winterer, Norman Zacharias, Florian Lammers-Lietz   +10 more
doaj   +1 more source

Prevalence and prognostic impact of cognitive frailty in elderly patients with heart failure: sub‐analysis of FRAGILE‐HF

ESC Heart Failure, 2022
Aims Although evidence suggests that cognitive decline and physical frailty in elderly patients with heart failure (HF) are associated with prognosis, the impact of concurrent physical frailty and cognitive impairment, that is, cognitive frailty, on ...
Shuhei Yamamoto, Saeko Yamasaki, Satoko Higuchi, Kentaro Kamiya, Hiroshi Saito, Kazuya Saito, Yuki Ogasahara, Emi Maekawa, Masaaki Konishi, Takeshi Kitai, Kentaro Iwata, Kentaro Jujo, Hiroshi Wada, Takatoshi Kasai, Hirofumi Nagamatsu, Tetsuya Ozawa, Katsuya Izawa, Naoki Aizawa, Akihiro Makino, Kazuhiro Oka, Shin‐ichi Momomura, Nobuyuki Kagiyama, Yuya Matsue   +22 more
doaj   +1 more source

Individuals With Multijoint Osteoarthritis Demonstrate Larger Longitudinal Declines in Frailty: Data From the Canadian Longitudinal Study on Aging

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to test the hypothesis that multijoint osteoarthritis would modify the relation between time and frailty progression, in which more affected joints would lead to larger declines over six years compared to those without osteoarthritis using data from the Canadian Longitudinal Study on Aging.
Carson Halliwell, Rebecca Moyer, Myles W. O'Brien   +2 more
wiley   +1 more source