Results 51 to 60 of about 2,466,460 (289)

Death-associated protein kinase 1-dependent SENP1 degradation increases tau SUMOylation and leads to cognitive dysfunction in a mouse model for tauopathy

Molecular Neurodegeneration
Background Emerging evidence implicates that tau SUMOylation disrupts tau homeostasis. Death-associated protein kinase 1 (DAPK1) has been shown to affect tau phosphorylation and accumulation.
Xindong Shui, Xiaoqing Zheng, Jinfeng Wu, Mi Zhang, Gamin Kim, Renxuan Chen, Lianlian Peng, Zonghai Wang, Yameng Zheng, Ling Zhang, Ruomeng Li, Long Wang, Ying Zhou, Jungho Kim, Dongmei Chen, Tao Zhang, Tae Ho Lee   +16 more
doaj   +1 more source

The structural and functional brain alternations in tobacco use disorder: a systematic review and meta-analysis

Frontiers in Psychiatry
BackgroundWhile numerous previous studies have indicated that nicotine intake results in gray matter and functional brain abnormalities in tobacco use disorder (TUD), the majority of results could not be replicated or even reversed.
Longyao Ma, Longyao Ma, Qiuying Tao, Qiuying Tao, Jinghan Dang, Jinghan Dang, Jieping Sun, Jieping Sun, Xiaoyu Niu, Xiaoyu Niu, Mengzhe Zhang, Mengzhe Zhang, Yimeng Kang, Yimeng Kang, Weijian Wang, Weijian Wang, Jingliang Cheng, Jingliang Cheng, Yong Zhang, Yong Zhang   +19 more
doaj   +1 more source

Enhancing Cognitive Function of Healthy Wistar Rats with Aqueous Extract of Centella Asiatica [PDF]

, 2018
Background: Centella asiatica (L.) Urb is a native herb from Asian countries such as India, China, and Indonesia. This herb has been widely used as a cure for various diseases.
Akib, A. (Abdurrahman), Husna, A. (Afkara), Khairunnisa, F. (Fadhila), Lusiana, E. (Evi), Reagan, M. (Muhammad), Rosdah, A. A. (Ayeshah)   +5 more
core  

Acute hypoglycemia impairs executive cognitive function in adults with and without type 1 diabetes [PDF]

, 2013
OBJECTIVE: Acute hypoglycemia impairs cognitive function in several domains. Executive cognitive function governs organization of thoughts, prioritization of tasks, and time management.
A. J. Graveling, Albinet, B. M. Frier, Berg, Cox, Elliott, Evans, Geddes, Goel, Gold, Gold, Hardy, Heller, Homack, I. J. Deary, Kerr, Maran, Pedersen-Bjergaard, Salthouse, Sommerfield, Sommerfield, Van der Elst, Warren   +22 more
core   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Diagnosis of Dementia and Cognitive Impairment

Diagnostics, 2019
In this special issue of Diagnostics, expert contributors have produced up-to-date research studies and reviews on various topics related to the diagnosis of dementia and cognitive impairment.
Andrew J. Larner
doaj   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Multisensory task demands temporally extend the causal requirement for visual cortex in perception

Nature Communications, 2022
How primary sensory cortices contribute to decision making remains poorly understood. Here the authors report that increasing task demands extend the temporal window in which the primary visual cortex is required for detecting identical stimuli.
Matthijs N. Oude Lohuis, Jean L. Pie, Pietro Marchesi, Jorrit S. Montijn, Christiaan P. J. de Kock, Cyriel M. A. Pennartz, Umberto Olcese   +6 more
doaj   +1 more source

Multivariate pattern analysis of electroencephalography data reveals information predictive of charitable giving

NeuroImage, 2021
Charitable donations are an altruistic behavior whereby individuals donate money or other resources to benefit others while the recipient is normally absent from the context. Several psychological factors have been shown to influence charitable donations,
Qiuyan Huang, Danyang Li, Can Zhou, Qiang Xu, Peng Li, Christopher M. Warren   +5 more
doaj   +1 more source

Smoking, childhood IQ and cognitive function in old age [PDF]

, 2012
Objectives: To examine the association between smoking history and cognitive function in old age, and whether it remains after controlling for childhood cognitive ability (IQ) and adult socioeconomic status (SES).Methods: In the Lothian Birth Cohort 1936
Corley, Janie, Deary, Ian J., Gow, Alan J., Starr, John M.   +3 more
core   +1 more source