Results 71 to 80 of about 1,757,542 (289)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Enhancing nursing students' cultural awareness through Community of Inquiry‐guided online ‘Internationalization at Home’ strategies—An intervention study

open access: yesNursing Open
Aim Internationalization at Home (IaH) strategies play an important role in nursing curricula to enhance nursing students' cultural awareness in the globalized world.
Siu Ling Chan   +8 more
doaj   +1 more source

Exploring the mediating effect of academic self-efficacy and self-regulated learning in the relationship between teaching, social presences and cognitive presence [PDF]

open access: yesJournal of Pedagogical Research
This study investigates vocational students’ blended learning from the perspective of the extended Community of Inquiry framework (incorporating learning presence as the fourth presence), and examine the mediating role of academic self-efficacy and self ...
Zidi Chen   +2 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Learner-Centered Design

open access: yesJournal of Effective Teaching in Higher Education, 2018
This quantitative research study examined one instructor’s redesign of her introductory Anthropology course (N = 265) from Teacher-Centered (TC) to Learning-Centered (LC) and the resulting impact on her students’ perceptions of Teaching Presence (TP ...
Sheri Stover, Ph.D.   +2 more
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Twin Memory [PDF]

open access: yes, 2016
In this article, I examine a new concept of “Twin Memory’ which has emerged in memory classification research of conscious and unconscious memory representations.
Rizvi, Syed Ismyl Mahmood
core  

Cognitive–linguistic deficit and speech intelligibility in chronic progressive multiple sclerosis [PDF]

open access: yes, 2009
Multiple sclerosis (MS) is a disabling neurological disease with varied symptoms, including dysarthria and cognitive and linguistic impairments. Association between dysarthria and cognitive-linguistic deficit has not been explored in clinical MS studies.
Green, Jan, Mackenzie, Catherine
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Presence and Prediction: The Embodied Reader's Cascades of Cognition

open access: yesStyle, 2014
Abstract What would a model of the embodied reader look like? Is he tied to the embodied resonances evoked by the text and by extension grounded in the here and now of the represented situation? Or can we integrate the dynamics of the plot in his reading experience? Can the embodied reader take a metaperspective, deciding whether what
openaire   +3 more sources

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