Results 61 to 70 of about 1,757,542 (289)

Cardiovascular autonomic function and MCI in Parkinson's disease [PDF]

, 2019
Introduction: dysautonomic dysfunction and cognitive impairment represent the most disabling non-motor features of Parkinson's Disease (PD). Recent evidences suggest the association between Orthostatic Hypotension (OH) and PD-Dementia. However, little is
Baschi R., Cicero C. E., Davi M., Donzuso G., Giuliano L., Luca A., Monastero R., Mostile G., Nicoletti A., Raciti L., Sciacca G., Terravecchia C., Zappia M.   +12 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

MEASURING THE COMMUNITY IN ONLINE CLASSES

Online Learning, 2013
The paper addresses individual and group level phenomena in online classes, and proposes both theoretical and empirical approaches to examining them, following the example of organizational climate.
Beth Rubin
doaj   +1 more source

Physical-Layer Security with Multiuser Scheduling in Cognitive Radio Networks

, 2013
In this paper, we consider a cognitive radio network that consists of one cognitive base station (CBS) and multiple cognitive users (CUs) in the presence of multiple eavesdroppers, where CUs transmit their data packets to CBS under a primary user's ...
Shen, Weiming, Wang, Xianbin, Zou, Yulong   +2 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A model of emotional influence on memory processing. [PDF]

, 2005
To survive in a complex environment, agents must be able to encode information about the utility value of the objects they meet. We propose a neuroscience-based model aiming to explain how a new memory is associated to an emotional response.
Chassy, P, Gobet, F
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The Impacts of Teaching Presence, Cognitive Presence and Social Presence on Student Engagement

Information Management and Business Review
Technology has undoubtedly enhanced the significance of convenience in learning, especially in tertiary educational institutions, as the dynamic integration between online and traditional learning is demonstrated. However, it is fair to debate whether this technology has also helped to enable the students to be more engaged in the classroom or whether ...
Nur Athirah Sumardi, Natasha Dzulkalnine, Ruzanifah Kosnin   +2 more
openaire   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Intentions, Intending, and Belief: Noninferential Weak Cognitivism [PDF]

, 2020
Cognitivists about intention hold that intending to do something entails believing you will do it. Non-cognitivists hold that intentions are conative states with no cognitive component. I argue that both of these claims are true. Intending entails the
Clark, Philip
core