Results 51 to 60 of about 363,866 (292)

Your click decides your fate: Inferring Information Processing and Attrition Behavior from MOOC Video Clickstream Interactions [PDF]

, 2014
In this work, we explore video lecture interaction in Massive Open Online Courses (MOOCs), which is central to student learning experience on these educational platforms.
Dillenbourg, Pierre, Jermann, Patrick, Li, Nan, Sinha, Tanmay   +3 more
core   +2 more sources

Characterizing the clinical heterogeneity of early symptomatic Alzheimer’s disease: a data-driven machine learning approach

Frontiers in Aging Neuroscience
IntroductionAlzheimer’s disease (AD) is highly heterogeneous, with substantial individual variabilities in clinical progression and neurobiology.
Xiwu Wang, Teng Ye, Deguo Jiang, Wenjun Zhou, Jie Zhang, for the Alzheimer’s Disease Neuroimaging Initiative   +5 more
doaj   +1 more source

Markers of cognitive function in individuals with metabolic disease: Morquio Syndrome and Tyrosinemia Type III [PDF]

, 2018
We characterized cognitive function in two metabolic diseases. MPS–IVa (mucopolysaccharidosis IVa, Morquio) and tyrosinemia type III individuals were assessed using tasks of attention, language and oculomotor function.
Blundell, James, Chakrapani, Anupam, Frisson, S., Gissen, Paul, Hendriksz, Chris, Kearney, Shauna, MacDonald, Anita, Olson, Andrew, Vijay, Suresh   +8 more
core   +3 more sources

Trajectories of Neuropsychiatric Symptoms and Cognitive Decline in Mild Cognitive Impairment [PDF]

The American Journal of Geriatric Psychiatry, 2016
To characterize the course of neuropsychiatric symptoms (NPS) in adults with mild cognitive impairment (MCI), and to examine baseline individual-level predictors and associated cognitive and functional outcomes.A 2-year prospective cohort study.Multicenter clinical settings.Five hundred sixty individuals with MCI at baseline.NPS severity (measured ...
David, Nicholas D, Lin, Feng, Porsteinsson, Anton P, Initiative, Alzheimer's Disease Neuroimaging   +3 more
openaire   +4 more sources

Association between early child development trajectories and adult cognitive function in a 50-year longitudinal study in Guatemala

BMJ Open, 2021
Objectives Few studies have used longitudinal data to study the development of cognition over the life course in low-income and middle-income countries.
Aryeh D Stein, María F Kroker-Lobos, Manuel Ramírez-Zea, Ines Gonzalez Casanova, Ann DiGirolamo, Laura Ochaeta, Reynaldo Martorell   +6 more
doaj   +1 more source

Bayesian latent time joint mixed-effects model of progression in the Alzheimer's Disease Neuroimaging Initiative. [PDF]

, 2018
IntroductionWe characterize long-term disease dynamics from cognitively healthy to dementia using data from the Alzheimer's Disease Neuroimaging Initiative.MethodsWe apply a latent time joint mixed-effects model to 16 cognitive, functional, biomarker ...
Aisen, Paul S, Donohue, Michael C, Iddi, Samuel, Li, Dan, Rafii, Michael S, Thompson, Wesley K   +5 more
core   +1 more source

Neighborhood disadvantage and children’s cognitive skill trajectories

Children and Youth Services Review, 2020
This study examined how neighborhood poverty is associated with children's trajectories of growth in math and reading skills in early elementary school, and how these associations vary by student characteristics, using multilevel growth models with nationally representative data from the 2011 Early Childhood Longitudinal Study-Kindergarten Cohort ...
Vinopal, Katie, Morrissey, Taryn W.
openaire   +2 more sources

Frailty, cognitive impairment, and depressive symptoms in Chinese older adults: an eight-year multi-trajectory analysis

BMC Geriatrics, 2023
Background Frailty, cognitive impairment, and depressive symptoms are closely interrelated conditions in the aging population. However, limited research has longitudinally analyzed the concurrent trajectories of these three prominent conditions in older ...
Yiyang Yuan, Changmin Peng, Jeffrey A. Burr, Kate L. Lapane   +3 more
doaj   +1 more source

Physical Activity and Cognitive Trajectories in Cognitively Normal Adults [PDF]

Alzheimer Disease & Associated Disorders, 2014
Increased physical activity may protect against cognitive decline, the primary symptom of Alzheimer disease. In this study, we examined the relationship between physical activity and trajectories of cognitive functioning over serial assessments. Cognitively normal (Clinical Dementia Rating 0) middle-aged and older adults (N=173; mean age, 60.7 ± 7.8 y)
Rachel, Pizzie, Halley, Hindman, Catherine M, Roe, Denise, Head, Elizabeth, Grant, John C, Morris, Jason J, Hassenstab   +6 more
openaire   +2 more sources

Early Life Experiences and Trajectories of Cognitive Development [PDF]

Pediatrics, 2020
BACKGROUND:Multiple factors constrain the trajectories of child cognitive development, but the drivers that differentiate the trajectories are unknown. We examine how multiple early life experiences differentiate patterns of cognitive development over the first 5 years of life in low-and middle-income settings.METHODS:Cognitive development of 835 ...
Benjamin J J, McCormick, Laura E, Caulfield, Stephanie A, Richard, Laura, Pendergast, Jessica C, Seidman, Angelina, Maphula, Beena, Koshy, Ladislaus, Blacy, Reeba, Roshan, Baitun, Nahar, Rita, Shrestha, Muneera, Rasheed, Erling, Svensen, Zeba, Rasmussen, Rebecca J, Scharf, Sayma, Haque, Reinaldo, Oria, Laura E, Murray-Kolb   +17 more
openaire   +2 more sources