Results 71 to 80 of about 2,345,325 (297)

Robot Excitation Trajectories for Dynamic Parameter Estimation using Optimized B-Splines [PDF]

open access: yes, 2012
In this paper we adressed the problem of finding exciting trajectories for the identification of manipulator link inertia parameters. This can be formulated as a constraint nonlinear optimization problem.
Hirzinger, Gerd   +5 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Global optimisation of multiple gravity assist trajectories [PDF]

open access: yes, 2010
Multiple gravity assist (MGA) trajectories represent a particular class of space trajectories in which a spacecraft exploits the encounter with one or more celestial bodies to change its velocity vector; they have been essential to reach high Delta-v ...
Ceriotti, M.
core   +4 more sources

Offloading Cognition onto Cognitive Technology [PDF]

open access: yes, 2008
"Cognizing" (e.g., thinking, understanding, and knowing) is a mental state. Systems without mental states, such as cognitive technology, can sometimes contribute to human cognition, but that does not make them cognizers.
Dror, I   +5 more
core   +1 more source

Preliminary design of multiple gravity-assist trajectories [PDF]

open access: yes, 2006
In this paper the preliminary design of multiple gravity-assist trajectories is formulated as a global optimization problem. An analysis of the structure of the solution space reveals a strong multimodality, which is strictly dependent on the complexity ...
Vasile, Massimiliano, De Pascale, Paolo
core   +5 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Relative Trajectories of Gait and Cognitive Decline in Aging

open access: yesThe Journals of Gerontology: Series A, 2021
Abstract Background Gait and cognition decline with advancing age, and presage the onset of dementia. Yet, the relative trajectories of gait and cognitive decline in aging are poorly understood—particularly among those with the motoric cognitive risk (MCR) syndrome.
Oshadi Jayakody   +7 more
openaire   +2 more sources

trajectories-alignment: gh page

open access: yes, 2016
Align enodocytic trajectories in space and time, compute their average trajectories, align different average trajectories together in space and ...
apicco
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

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