Results 31 to 40 of about 9,925 (261)

Finite Element Analysis for Brittle and Ductile Fracture Using a Unified Cohesive Zone Model

open access: yesAdvances in Mechanical Engineering, 2013
A unified cohesive zone model is proposed. By introducing a parameter which denotes the ductility of the material, the proposed model can be used to simulate both brittle and ductile fracture.
Jinxiang Liu, Jun Li, Litao Liu
doaj   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

Investigating Ice Loads on Subsea Pipelines with Cohesive Zone Model in Abaqus

open access: yesModelling, 2023
Subsea pipelines and cables placed in ice-prone regions may be at risk of iceberg damage. In particular, pipes that are not buried may come in direct contact with iceberg keels.
Igor Gribanov   +3 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Crack nucleation in circular disk under mixed boundary conditions

open access: yesArchives of Mechanics, 2015
A model of crack nucleation in a circular disk, based on consideration of cracking process zone is suggested. It is assumed that the cracking process zone is a finitelength layer containing a material with partially disturbed bonds between separate ...
V.M. Mirsalimov, N.M. Kalantarly
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez   +5 more
wiley   +1 more source

On the calibration of the cohesive strength for cohesive zone models in finite element analyses

open access: yesTheoretical and Applied Fracture Mechanics, 2022
Abstract Cohesive zone models are commonly used to numerically model fracture phenomena on the microscale. Typical fracture processes are described experimentally via the Double Cantilever Beam test and the End Notched Flexure test on the macroscale. Analytical solutions, e.g. the LEFM-based beam theory, are used to evaluate these tests
Max Linke, Rolf Lammering
openaire   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

open access: yesAdvanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar   +2 more
wiley   +1 more source

Rafting of Ni‐Based Superalloys Under Multiaxial Load as Understood by Phase‐Field Simulations and Critical Experiments

open access: yesAdvanced Engineering Materials, EarlyView.
Phase‐field simulations coupled with dislocation‐density‐based crystal plasticity modeling reproduce γ′ rafting behavior in single‐crystal Ni‐based superalloys under varied loading conditions. The model captures both macroscopic creep and microscopic morphology evolution, with results matching high‐temperature creep experiments.
Micheal Younan   +5 more
wiley   +1 more source

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