Results 121 to 130 of about 2,873,998 (272)

Similarity-Informed Transfer Learning for Multivariate Functional Censored Quantile Regression [PDF]

arXiv
To address the challenge of utilizing patient data from other organ transplant centers (source cohorts) to improve survival time estimation and inference for a target center (target cohort) with limited samples and strict data-sharing privacy constraints, we propose the Similarity-Informed Transfer Learning (SITL) method.
arxiv  

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source

Correction: Risk of epilepsy after febrile convulsions: a national cohort study [PDF]

, 1992

openalex   +1 more source

The value of fetal growth trajectory during pregnancy in predicting small for gestational age neonates at term

BMC Pregnancy and Childbirth
Background The predictive value of trajectory identified by group-based trajectory modeling (GBTM) has been discussed but its value in predicting small for gestational age (SGA) neonates is still unclear.
Huimin Zhu, Min Wei, Xiuxiu Li, Xuemei Liu, Jin Li, Xuemei Fan, Zhen Wang, Weiqing Chen   +7 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Retrospective cohort mortality study of workers at an aircraft maintenance facility. I. Epidemiological results. [PDF]

, 1991
Robert Spirtas, Patricia A. Stewart, J S Lee, Donald E. Marano, C D Forbes, D. Grauman, Hugh M. Pettigrew, A. Blair, Robert N. Hoover, J L Cohen   +9 more
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Harnessing Increased Client Participation with Cohort-Parallel Federated Learning [PDF]

arXiv
Federated learning (FL) is a machine learning approach where nodes collaboratively train a global model. As more nodes participate in a round of FL, the effectiveness of individual model updates by nodes also diminishes. In this study, we increase the effectiveness of client updates by dividing the network into smaller partitions, or cohorts.
arxiv  

A Cohort Study on the Mass Examination of Cardiovascular Disorder

, 1968
Hideo Kaneko
openalex   +2 more sources

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source