Results 11 to 20 of about 21,356 (260)

Differential expression of COL3A1 in pancreatic cancer.

, 2023
Cancer is a leading cause of death and pancreatic cancer is among the most lethal cancers (1, 2). We mined published and public microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with pancreatic cancer, pancreatic adenocarcinoma ...
Shahan Mamoor
openaire   +2 more sources

COL3A1 2209G>A is a predictor of pelvic organ prolapse [PDF]

International Urogynecology Journal, 2009
A familial tendency has been demonstrated in the etiology of pelvic organ prolapse (POP), but the specific genetic defects have not been identified. Type III collagen is an important factor in the repair of connective tissue, and gene polymorphisms may impair the tensile strength.
Kluivers, K.B., Dijkstra, J.R., Hendriks, J.C.M., Lince, S.L., Vierhout, M.E., Kempen, L.C.L.T. van   +5 more
openaire   +4 more sources

Effect of silencing Thrips palmi Btk29A and COL3A1 on fitness and virus acquisition

Frontiers in Microbiology, 2023
Thrips palmi (Thysanoptera: Thripidae) is a major agricultural pest infesting over 200 plant species. Along with direct injury caused by feeding, T. palmi spreads several orthotospoviruses.
Vavilapalli Rajesh, Vavilapalli Rajesh, Sumit Jangra, Amalendu Ghosh   +3 more
doaj   +3 more sources

Loss of Col3a1, the gene for Ehlers-Danlos syndrome type IV, results in neocortical dyslamination. [PDF]

PLoS ONE, 2012
It has recently been discovered that Collagen III, the encoded protein of the type IV Ehlers-Danlos Syndrome (EDS) gene, is one of the major constituents of the pial basement membrane (BM) and serves as the ligand for GPR56.
Sung-Jin Jeong, Shihong Li, Rong Luo, Natalie Strokes, Xianhua Piao   +4 more
doaj   +3 more sources

Upregulation of COL3A1 is a Key Driver in Kidney Stone Formation

Frontiers in Bioscience-Landmark
Background: Kidney stones are a globally prevalent condition, but their pathogenesis remains incompletely understood. This study aimed to identify and validate key genes implicated in kidney stone formation through sequencing data ...
Hua Jiang, Yanji Jiang, Jie Ji, Anyang Chou, Weipu Mao, Ming Chen, Yang Zheng   +6 more
doaj   +3 more sources

LAMB1 regulates COL3A1 and RAC1 expression during subchorionic hemorrhage progression

BMC Biology
Background Subchorionic hemorrhage (SCH) is characterized by a fluid-filled hypoechoic area in early pregnancy. This study investigates how laminin subunit β1 (LAMB1) modulates type III collagen (COL3A1) and Rac family small GTPase 1 (RAC1) in SCH ...
Qian Sun, Xiaoyan Wu, Xiaopei Li, Fan Shi, Yuan Gao, Jing Ji, Guixue Guan, Jinjin Xu, Linna Zhang, Xiaozuo Zhang, Yuhuan Wang, Wen Feng, Shun Liu, Hengmin Bi, Conghui Han, Zuobin Zhu, Wen Yang   +16 more
doaj   +3 more sources

Phenotype of COL3A1/COL5A2 deletion patients

European Journal of Medical Genetics, 2022
The diagnosis of Ehlers-Danlos syndrome is usually based on well-defined diagnostic criteria and the result of DNA investigation. Classical (cEDS) and vascular type (vEDS) are the most prevalent subtypes and are caused by heterozygous pathogenic variants in COL5A1, COL5A2, COL1A1 or, respectively, in COL3A1.
Marlies JE. Kempers, Marja Wessels, An Van Berendoncks, Ingrid MBH. van de Laar, Nicole de Leeuw, Bart Loeys   +5 more
openaire   +5 more sources

Radiation increases COL1A1, COL3A1, and COL1A2 expression in breast cancer [PDF]

Open Medicine, 2022
Abstract Background Radiotherapy-associated secondary cancer is an important issue for the treatment of breast cancer (BCa). This study aimed to investigate the molecular mechanism and genetic risk factors for radiation-associated secondary diseases in BCa.
Guorong Yao, Kaiyue Zhao, Kaikai Bao, Jing Li   +3 more
openaire   +3 more sources

In vivo aorta diameter measured in 6-week-old Col3a1^+/+ and Col3a1^+/G182R mice by ultrasound.

, 2022
A. Ascending and descending thoracic aorta in Col3a1+/G182R. White arrows indicate the ascending and descending thoracic aortic diameter. B. Abdominal aorta in Col3a1+/G182R. Blue arrow indicates the abdominal aortic diameter. C-D.
Irmine Loisel-Ferreira (12197672), Julie Faugeroux (160678), Carole Beugnon (12197666), Salma Adham (11793374), Charline Guery (515320), Anne Legrand (11793380), Xavier Jeunemaitre (75863), Juliette Hadchouel (160693), Erika Fontaine (12197663), Amélie Gianfermi (12197669), Marie-Christine Verpont (8358036), Tristan Mirault (541128)   +11 more
core   +1 more source

COL3A1 Overexpression Associates with Poor Prognosis and Cisplatin Resistance in Lung Cancer

Balkan Medical Journal, 2022
Background: Collagen type III alpha 1 chain (COL3A1) is reported to mediate drug resistance in various cancers, and public database analysis indicated its overexpression in lung cancer.
Lihuai Wang, Yinhui Sun, Zhongcong Guo, Hua Liu   +3 more
doaj   +1 more source