Results 21 to 30 of about 21,356 (260)

Heterogeneity of collagen fibers in Col3a1^+/G182R mice.

, 2022
The proportion (%) of collagen fibrils with a given diameter (nm) shows heterogeneity in the distribution for Col3a1+/G182R mice compared to Col3a1+/+ controls in the aorta. In the table, the diameters of the collagen fibrils show a wider range in Col3a1+
Irmine Loisel-Ferreira (12197672), Julie Faugeroux (160678), Carole Beugnon (12197666), Salma Adham (11793374), Charline Guery (515320), Anne Legrand (11793380), Xavier Jeunemaitre (75863), Juliette Hadchouel (160693), Erika Fontaine (12197663), Amélie Gianfermi (12197669), Marie-Christine Verpont (8358036), Tristan Mirault (541128)   +11 more
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Normal BP in Col3a1^+/G182R mice and decrease on Losartan.

, 2022
A. Day SBP before (4 days = basal) or during oral administration (4 days) of losartan (135 mg/kg/day) in Col3a1+/G182R mice (n = 8) compared to Col3a1+/+ mice (n = 7) examined with a telemetric system. B.
Irmine Loisel-Ferreira (12197672), Julie Faugeroux (160678), Carole Beugnon (12197666), Salma Adham (11793374), Charline Guery (515320), Anne Legrand (11793380), Xavier Jeunemaitre (75863), Juliette Hadchouel (160693), Erika Fontaine (12197663), Amélie Gianfermi (12197669), Marie-Christine Verpont (8358036), Tristan Mirault (541128)   +11 more
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VGLL4 inhibits stemness and cisplatin resistance in non-small cell lung cancer via the COL3A1/NF-κB pathway [PDF]

Journal of Men's Health
Previous studies have confirmed that vestigial-like protein 4 (VGLL4) can inhibit the malignant progression of lung cancer cells. However, its impact on cisplatin resistance and stemness in lung cancer cells remains unclear.
Jijun Xue, Qin Ma, Wenfeng Han
doaj   +1 more source

Case report: Characterization of a rare pathogenic variant associated with loss of COL3A1 expression in vascular Ehlers Danlos syndrome

Frontiers in Cardiovascular Medicine, 2022
The vascular subtype of Ehlers Danlos Syndrome (vEDS) is a rare connective tissue disorder characterized by spontaneous arterial, bowel or organ rupture.
Janvie Manhas, Lov Raj Lohani, Ashikh Seethy, Uma Kumar, Shivanand Gamanagatti, Sudip Sen   +5 more
doaj   +1 more source

Col3a1^+/G182R aortas have abnormal extracellular matrix architecture.

, 2022
A-F electron microscopy images of the thoracic aorta in 24-week-old Col3a1+/+ and Col3a1+/G182R mice (n = 3 per group). N = nucleus, ECM = extracellular matrix, RER = rough endoplasmic reticulum. Scale bar = 500 nm.
Irmine Loisel-Ferreira (12197672), Julie Faugeroux (160678), Carole Beugnon (12197666), Salma Adham (11793374), Charline Guery (515320), Anne Legrand (11793380), Xavier Jeunemaitre (75863), Juliette Hadchouel (160693), Erika Fontaine (12197663), Amélie Gianfermi (12197669), Marie-Christine Verpont (8358036), Tristan Mirault (541128)   +11 more
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Enhancing dermal collagen density towards youthfulness: A comparative study of PCL, PLLA, and PDO thread implantation in aging rats model [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Both intrinsic and extrinsic factors cause skin aging. Intrinsic aging is characterized by decreased collagen density, particularly collagen types I (COL1A1) and III (COL3A1), and an increase in the COL1/COL3 ratio.
Mary Soen, Meilinah Hidayat, Wahyu Widowati   +2 more
doaj   +1 more source

Role of COL3A1 and POSTN on Pathologic Stages of Esophageal Cancer

Technology in Cancer Research & Treatment, 2020
Background: Esophageal cancer (EC) is a primary malignant tumor originating from the esophageal of the epithelium. Surgical resection is a potential treatment for EC, but this is only appropriate for patients who have locally resectable lesions suitable for surgery.
Shao-wei Zhang, Nan Zhang, Na Wang
openaire   +3 more sources

Expression of Col3a1 gene and collagen III in aortas of Col3a1^+/G182R mice.

, 2022
A Relative allele specific mRNA expression of type III collagen in thoracic aorta of Col3a1+/+ (n = 21) and Col3a1+/G182R (n = 18) 24-week-old mice of both sexes determined by ddPCR.
Irmine Loisel-Ferreira (12197672), Julie Faugeroux (160678), Carole Beugnon (12197666), Salma Adham (11793374), Charline Guery (515320), Anne Legrand (11793380), Xavier Jeunemaitre (75863), Juliette Hadchouel (160693), Erika Fontaine (12197663), Amélie Gianfermi (12197669), Marie-Christine Verpont (8358036), Tristan Mirault (541128)   +11 more
core   +1 more source

Survival rate and basal hemodynamic parameters of Col3a1^+/G182R mice.

, 2022
A Kaplan-Meier Survival curve for comparing col3a1+/+ (n = 62) to Col3a1+/G182R (n = 76) and to Col3a1G182R/G182R (n = 10), which die from vascular rupture or dissection. Significant differences are calculated using Log-Rank (Mantel-Cox) analysis.
Irmine Loisel-Ferreira (12197672), Julie Faugeroux (160678), Carole Beugnon (12197666), Salma Adham (11793374), Charline Guery (515320), Anne Legrand (11793380), Xavier Jeunemaitre (75863), Juliette Hadchouel (160693), Erika Fontaine (12197663), Amélie Gianfermi (12197669), Marie-Christine Verpont (8358036), Tristan Mirault (541128)   +11 more
core   +1 more source

The Haploinsufficient Col3a1 Mouse as a Model for Vascular Ehlers-Danlos Syndrome [PDF]

Veterinary Pathology, 2010
Vascular Ehlers-Danlos syndrome is a rare genetic disorder resulting from mutations in the α-1 chain of type III collagen ( COL3A1) and manifesting as tissue fragility with spontaneous rupture of the bowel, gravid uterus, or large or medium arteries. The heterozygous Col3a1 knockout mouse was investigated as a model for this disease.
Cooper, T. K., Zhong, Q., Krawczyk, M., Tae, H-J., Müller, G. A., Schubert, Rudolf, Myers, L. A., Dietz, H. C., Talan, M. I., Briest, W.   +9 more
openaire   +3 more sources