Results 31 to 40 of about 21,356 (260)

A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses

Animals, 2023
Fractures caused by bone overloading are a leading cause of euthanasia in Thoroughbred racehorses. The risk of fatal fracture has been shown to be influenced by both environmental and genetic factors but, to date, no specific genetic mechanisms ...
Esther Palomino Lago, Arabella Baird, Sarah C. Blott, Rhona E. McPhail, Amy C. Ross, Sian A. Durward-Akhurst, Deborah J. Guest   +6 more
doaj   +1 more source

Relative mRNA expression of HSP47, ATF6, ATG5 and ATG7 in thoracic aorta of Col3a1^+/G182R and Col3a1^+/+ mice determined by q-PCR.

, 2022
The expression of HSP47, ATF6, ATG5 and ATG7 is significantly different in the thoracic aorta of Col3a1+/G182R mice compared to Col3a1+/+ controls (Student t-test, p (TIFF)
Irmine Loisel-Ferreira (12197672), Julie Faugeroux (160678), Carole Beugnon (12197666), Salma Adham (11793374), Charline Guery (515320), Anne Legrand (11793380), Xavier Jeunemaitre (75863), Juliette Hadchouel (160693), Erika Fontaine (12197663), Amélie Gianfermi (12197669), Marie-Christine Verpont (8358036), Tristan Mirault (541128)   +11 more
core   +1 more source

Genetic testing for vascular Ehlers-Danlos syndrome and other variants with fragility of the middle arteries

The EuroBiotech Journal, 2018
Ehlers-Danlos syndrome (EDS) is an umbrella term for various inherited connective tissue disorders associated with mutations in genes involved in extracellular matrix formation.
Rakhmanov Yeltay, Maltese Paolo Enrico, Bruson Alice, Castori Marco, Beccari Tommaso, Dundar Munis, Bertelli Matteo   +6 more
doaj   +1 more source

RNAi‐mediated inhibition of COL1A1 and COL3A1 in human skin fibroblasts [PDF]

Experimental Dermatology, 2007
Abstract:  Types I and III collagens are the major collagens comprising skin connective tissue. Defects in these collagens lead to diseases of dermal connective tissue and fibre hyperplasia. RNA interference (RNAi) provides a powerful tool to inhibit specific gene expression.
Qiong, Wang, Zhenhui, Peng, Shengxiang, Xiao, Songmei, Geng, Jingyi, Yuan, Zhengxiao, Li   +5 more
openaire   +2 more sources

COL3A1 rs1800255 polymorphism is associated with pelvic organ prolapse susceptibility in Caucasian individuals: Evidence from a meta-analysis.

PLoS ONE, 2021
BackgroundThe collagen 3 alpha 1 (COL3A1) rs1800255 polymorphism has been reported to be associated with women pelvic organ prolapse (POP) susceptibility, but the results of these previous studies have been contradictory.
Ke Niu, Xu Chen, Yongxian Lu
doaj   +1 more source

Comprehensive analysis of endoplasmic reticulum-related and secretome gene expression profiles in the progression of non-alcoholic fatty liver disease

Frontiers in Endocrinology, 2022
Endoplasmic reticulum (ER) is the principal organelle for protein synthesis, such as hepatokines and transmembrane proteins, and is critical for maintaining physiological function. Dysfunction of ER is associated with metabolic disorders.
Rong Gao, Jin Wang, Xuemin He, Tongtong Wang, Li Zhou, Zhitao Ren, Jifeng Yang, Xiaoxin Xiang, Shiyi Wen, Zhuojun Yu, Heying Ai, Yuchan Wang, Hua Liang, Shasha Li, Yan Lu, Yanhua Zhu, Guojun Shi, Yanming Chen   +17 more
doaj   +1 more source

COL3A1 and Its Related Molecules as Potential Biomarkers in the Development of Human Ewing’s Sarcoma [PDF]

BioMed Research International, 2021
Background. Ewing’s sarcoma (ES) is the most common malignant primary bone tumor in children and adolescents. This study is aimed at developing new prognostic markers and building a microRNA‐mRNA network in the development of ES. Method. GSE80201 and GSE39262 were downloaded from the Gene Expression Omnibus (GEO) database.
Min Tang, Peiqing Liu, Xiaoke Wu, Jie Gong, Jiacheng Weng, Guangyu Gao, Yulong Liu, Lei Gan   +7 more
openaire   +2 more sources

COL3A1对胃癌细胞增殖及侵袭影响的实验研究

Zhongguo shiyan zhenduanxue, 2022
目的 研究COL3A1在胃癌细胞增殖、迁移及侵袭过程中的作用。方法 以靶向COL3A1的干扰慢病毒（3个靶点）及阴性对照慢病毒转染胃癌细胞株MGC803，嘌呤霉素筛选稳转细胞株。qRT-PCR验证转染后MGC803细胞中COL3A1的mRNA表达，筛选出2个转染效率最高的细胞株，再以Western blot法进一步检测转染后胃癌细胞中COL3A1的蛋白表达量。采用MTT、Transwell法检测COL3A1干扰组、对照组胃癌细胞增殖、侵袭、迁移表型，观察COL3A1敲减前后胃癌细胞生物学特性的变化。结果
姜洪伟, 胡琦, 王举, 白钰灵, 套格苏, 李海军, 胡锦峰   +6 more
doaj  

Soft Tissues: Lipoblastoma with t(2;8)(q31;q12.1) COL3A1/PLAG1 [PDF]

, 2015
Review on lipoblastoma with t(2;8)(q31;q12.1) COL3A1/PLAG1, with data on clinics, and the genes ...
Miyachi, Mitsuru, Yoshida, Hideki, Hosoi, Hajime   +2 more
core   +1 more source

Immunofluorescence of descending TA sections in Col3a1^+/G182R mice.

, 2022
A. Immunofluorescent staining of descending TA sections of Col3a1+/+ (n = 10) and Col3a1+/G182R (n = 10) mice to show the distribution of collagens I and III.
Irmine Loisel-Ferreira (12197672), Julie Faugeroux (160678), Carole Beugnon (12197666), Salma Adham (11793374), Charline Guery (515320), Anne Legrand (11793380), Xavier Jeunemaitre (75863), Juliette Hadchouel (160693), Erika Fontaine (12197663), Amélie Gianfermi (12197669), Marie-Christine Verpont (8358036), Tristan Mirault (541128)   +11 more
core   +1 more source