Results 141 to 150 of about 86,831 (312)
Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors
British Journal of Pharmacology, EarlyView.Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen +3 more
wiley +1 more source
Separation of lymphocytes by electrophoresis under terrestrial conditions and at zero gravity, phase 3 [PDF]
Electrophoretic mobilities (EPM) of peripheral lymphocytes were studied from normal subjects, chronic hemodialysis patients and kidney transplant recipients.
Cheigh, J. S. +4 more
core +1 more source
BRIEF PAPERS: A TECHNIQUE FOR TREATING SMALL SEEDLINGS WITH COLCHICINE [PDF]
, 1943 Ross C. Thompson
openalex +1 more source
British Journal of Pharmacology, EarlyView.▪ Background and Purpose NLRP3 is up‐regulated in inflammatory and autoimmune diseases. The development of NLRP3 inhibitors is challenged by the identification of compounds with distinct mechanisms of action avoiding side effects and toxicity. Triptolide is a natural product with multiple anti‐inflammatory activities, but a narrow therapeutic window ...
Mo‐Yu Ding +5 more
wiley +1 more source
Effect of Colchicine Treatment on the Alkaloidal Content of Datura metel [PDF]
, 1948 A. E. Beesley, G. E. Foster
openalex +1 more source
Cell Proliferation, EarlyView.Schematic representation of generation of 8‐gene‐edited cloned pigs and their verification by pig to non‐human primate kidney xenotransplantation. ABSTRACT Gene‐edited (GE) pig‐to‐human xenotransplantation continues to make breakthroughs, but which kind of gene combination is suitable for organ‐specific transplantation remains unclear.
Jiaoxiang Wang +23 more
wiley +1 more source
Genome Structural-Functional Peculiarities Affecting Plant Epigenetic Variability and Evolution [PDF]
, 2010 There is an attempt to explain some evolutionary processes in plants such as saltatory changes on the base of multidimensionality of plant inherited information coding.
Evgenii Levites
core +1 more source
Recent advances in multimodality imaging‐guided therapy in pericarditis
European Journal of Clinical Investigation, EarlyView.Multiple imaging targets have been identified as essential biomarkers to confirm pericardial thickening, edema, neovascularization, inflammation, fibrosis/calcification, cardiac tamponade physiology, and constriction. This novel approach is called imaging‐guided therapy, which guides anti‐inflammatory therapy, assesses treatment response, assists in ...
Joseph El Roumi +4 more
wiley +1 more source
Journal of the European Academy of Dermatology and Venereology, EarlyView.Multiple inflammatory, infectious and autoimmune dermato‐venereological conditions are associated with erectile dysfunction (ED) due to underlying intricate vasculogenic, neurogenic, endocrine and psychogenic mechanisms. It is recommended that practitioners screen dermatology patients for ED and associated comorbidities, provide personalized lifestyle ...
Andrei Tanasov, George‐Sorin Tiplica
wiley +1 more source