Letter by Kakizaki and Räber Regarding Article, “Effect of Colchicine on Coronary Plaque Stability in Acute Coronary Syndrome as Assessed by Optical Coherence Tomography: The COLOCT Randomized Clinical Trial” [PDF]
Ryota Kakizaki, Lorenz Räber
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Cellular Senescence, Inflammaging and Cardiovascular Disease
ABSTRACT Aging is the most important yet unmodifiable risk factor for cardiovascular disease (CVD). As a result, targeting cardiovascular aging has emerged as a promising strategy to promote long‐term cardiovascular health. This review summarizes current knowledge on the effects of aging within the cardiovascular system as well as systemic processes ...
Lukas Zanders +3 more
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Colchicine for Prevention of Recurrent Stroke-Are we CONVINCED? [PDF]
De Marchis GM +3 more
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Effect of cytochalasin B on the induction of chromosome missegregation by colchicine at low concentrations in human lymphocytes [PDF]
Sandra Minissi
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The Immunological Consequences of Clonal Hematopoiesis in Heart Failure
ABSTRACT Inflammation is increasingly recognized as a central driver of heart failure (HF), particularly in older adults, yet the underlying immune mechanisms remain diverse and incompletely understood. Clonal hematopoiesis (CH), defined by the expansion of somatically mutated hematopoietic clones, has emerged as a risk factor for the development of ...
Megan A. Evans, Kenneth Walsh
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Anti-inflammatory pharmacotherapy in patients with cardiovascular disease. [PDF]
Finocchiaro S +14 more
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The Effect of Low‐Dose Colchicine on the Phenotype and Function of Neutrophils and Monocytes in Patients with Chronic Coronary Artery Disease: A Double‐Blind Randomized Placebo‐Controlled Cross‐Over Study [PDF]
Helin Tercan +10 more
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Trained Immunity and Cardiovascular Risk: An Immunological Perspective
ABSTRACT Systemic inflammation is a key driver of atherogenesis and its complications. While anti‐inflammatory therapies targeting pathways such as IL‐1β and IL‐6 have shown promise in established atherosclerotic cardiovascular disease (ASCVD), potential systemic effects raise concerns about immune suppression and infection, underscoring the need for ...
Katherine A. Boden +3 more
wiley +1 more source
Colchicine inhibition of microtubule assembly via copolymer formation.
H. Sternlicht, Israel Ringel
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