Results 41 to 50 of about 86,831 (312)

The etiology and autopsy findings in Colchicine intoxication-related deaths

open access: yesMedicine Science, 2016
Colchicine is a drug which has a very narrow therapeutic range. This drug has been commonly used for Familial Mediterranean Fever (FMF), Behcet’s disease, gout arthritis and acute pseudo gout attacks.
Servet Birgin Iritas   +7 more
doaj   +1 more source

Successfully Treated Severe Colchicine Intoxication in an Adolescent

open access: yesTürk Yoğun Bakim Derneği Dergisi, 2022
The contain is extracted from the autumn crocus plant, colchicine that an anti-inflammatory drug. The use of colchicine impairs mobilization and activation of neutrophil and supporting treating from some rheumatological diseases especially in childhood ...
Hatice Feray Arı   +2 more
doaj   +1 more source

Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules [PDF]

open access: yes, 2017
Tubulin-targeting molecules are widely used cancer therapeutic agents. They inhibit microtubule-based structures, including the mitotic spindle, ultimately preventing cell division.
Coluccia, Antonio   +10 more
core   +1 more source

Rhabdomyolysis associated with concomitant use of colchicine and statins in the real world: identifying the likelihood of drug–drug interactions through the FDA adverse event reporting system

open access: yesFrontiers in Pharmacology
BackgroundCurrently, there remains substantial controversy in research regarding whether the concomitant use of colchicine and statins increases the occurrence of rhabdomyolysis, warranting further substantiation.ObjectiveThis study aimed to identify the
Sha Zhang   +4 more
doaj   +1 more source

Effect of Treatment with Colchicine after Acute Coronary Syndrome on Major Cardiovascular Events: A Systematic Review and Meta-Analysis of Clinical Trials

open access: yesCardiovascular Therapeutics, 2022
Aim. Colchicine as an anti-inflammatory drug might be effective in the treatment of atherosclerosis, an inflammatory-based condition. The aim of this systematic review and meta-analysis was to evaluate the impact of colchicine on acute coronary syndrome (
Erfan Razavi   +3 more
doaj   +1 more source

Seed Germination and Seedling Growth of Dendrocalumus brandisii in vitro, and the Inhibitory Mechanism of Colchicine

open access: yesFrontiers in Plant Science, 2021
Bamboos seldom bloom and almost no seeds could be harvested, and, hence, few works are focused on germination physiology. Systematic research on the physiological effects of colchicine on germination and seedling growth of bamboo seeds is lacking.
Zhuo Lv   +9 more
doaj   +1 more source

Repurposing screen identifies mebendazole as a clinical candidate to synergise with docetaxel for prostate cancer treatment [PDF]

open access: yes, 2020
BACKGROUND: Docetaxel chemotherapy in prostate cancer has a modest impact on survival. To date, efforts to develop combination therapies have not translated into new treatments. We sought to develop a novel therapeutic strategy to tackle chemoresistant
Dufès, Christine   +9 more
core   +3 more sources

Colchicine in overdose [PDF]

open access: yesBritish Journal of General Practice, 2016
Would colleagues please be aware of the devastating consequences of a significant colchicine …
openaire   +3 more sources

Risk of coronary artery disease in patients with gout on treatment with Colchicine: A systematic review and meta-analysis

open access: yesInternational Journal of Cardiology: Heart & Vasculature, 2023
Background: Colchicine has anti-inflammatory properties, but its utility in improving cardiovascular outcomes has been disputed. Here, we study the impact of colchicine on cardiovascular outcomes in patients with gout with and without coronary artery ...
Muhammad U. Siddiqui   +5 more
doaj  

Colchicine-induced myoneuropathy in a cyclosporine-treated renal transplant recipient

open access: yesKidney Research and Clinical Practice, 2013
Colchicine is a relatively safe medication that is widely used for both prevention and treatment of gout attack. However, serious adverse events, including myoneuropathy and multiorgan failure, have been reported.
Kyungmin Huh   +6 more
doaj   +1 more source

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