Results 61 to 70 of about 3,581,165 (352)

A continuum model accounting for the effect of the initial and evolving microstructure on the evolution of dynamic recrystallization [PDF]

, 2017
Laser assisted forming is a process which is increasingly being adopted by the industry. Application of heat by a laser to austenitic stainless steel (ASS) sheet provides local control over formability and strength of the material.
Kooiker, Harm, Perdahcioglu, Emin S., Van den Boogard, Ton   +2 more
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

THERMAL EFFECT ANALYSIS OF ROLLING FRICTION IN HIGH SPEED COLD ROLL-BEATING FORMING

Jixie qiangdu, 2018
High-speed cold forming is a complex forming process coupling under multi factors, which has the rolling friction affecting the fluidity of the workpiece metal, and then affecting the quality and performance of the forming parts.
LI YuXi, LI Yan, CUI LiMu, XIAO JiMing, CUI FengKui   +4 more
doaj  

Influence of tool wear on material flow [PDF]

, 2017
The cold bulk forming is a technology that is commonly used in many industrial enterprises. Even though nowadays high demands are posed on labour productivity, quality and own production costs, the findings from practice suggest that not sufficient ...
Schindlerová, Vladimíra, Šajdlerová, Ivana   +1 more
core   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

RESEARCH ON THE IMPACT OF FRICTION COEFFICIENT TO SCALE IN COLD ROLL-BEATING FORMING

Jixie qiangdu, 2017
Scale of forming surface in cold roll-beating forming process is a major defect. Controlling scaly defects is an important method to improve forming surface quality.
FENG JingMin, LI Yan, YANG MingShun, LIANG XiaoMing   +3 more
doaj  

Prediction and Prevention of Edge Waves in Continuous Cold Forming of Thick-Wall High-Strength Welded Pipe

Metals
In order to reduce the edge waves and defects of the strip in the forming process and obtain better properties of the strip, it is urgent to establish a better flexible cold forming process.
Shengde Hu, Junhao Zhao, Yu Liu
doaj   +1 more source

Implementation of the Bai and Wierzbicki fracture criterion in QForm and its application for cold metal forming and deep drawing technology [PDF]

, 2015
The paper presents implementation of fracture prediction algorithm for a cold metal forming process simulation in the software QForm. Authors programmed the function for calculation of the criterion proposed by Bai and Wierzbicki. Obtained results of the
Behrens, Bernd-Arno, Bouguecha, Anas, Gladkov, Yury, Peshekhodov, Ilya, Vucetic, Milan   +4 more
core   +2 more sources

A model of particles cold forming as collapsed Bose–Einstein condensate of gammons

, 2018
Commentary In a previous paper1 were presented briefly some basic particle models resulted from a cold genesis theory of matter and fields2–5 of the author, (CGT), regarding the cold forming process of cosmic elementary particles, formed–according to the
Marius Arghirescu
semanticscholar   +1 more source