Results 71 to 80 of about 12,584,658 (247)

Process chain simulation of laser cladding and cold metal forming

, 2022
S.337-352Lightweight construction is still an important driver for innovations in production technologies. Recent developments in Laser Metal Deposition (LMD) and forming technology allow the production of lightweight sheet metal components with locally ...
Khazan, P., Hama-Saleh, Rebar, Kzzo, A., Ünsal, I., Weisheit, Andreas, Bambach, M.   +5 more
core   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Finite element simulation of stretch forming of aluminium-polymer laminate foils used for pharmaceutical packaging

MATEC Web of Conferences, 2016
Pharmaceutical high barrier blister packages are manufactured from aluminium-polymer laminate foils (e.g. consisting of PA-Al-PVC layers). By a cold stretch forming process cavities are formed.
Müller Simon, Weygand Sabine M.
doaj   +1 more source

Prediction of Roll Profile Wear in the Cold Roll Forming Process

, 2009
This paper presents a model for prediction of forming roll profile wear during the cold roll forming process. The method is based on contact pressure distribution, geometrical description of the initial forming roll profile and NURBS representation of ...
Galakhar, A., Meehan, P.A., Daniel, W.J.T.   +2 more
core   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Simulation of tool load for axial forming process with oscillating feed

, 2013
The axial forming process is a method of cold metal forming, which is used for the production of axially symmetric profiles and retractions at full and hollow components.
Lahl, Mike, Popp, Mike, Schuster, Robert, Milbrandt, Matthias, Porstmann, Sebastian, Schiller, Sven, Druwe, Thomas   +6 more
core   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Coating-substrate-simulations applied to HFQ® forming tools

MATEC Web of Conferences, 2015
In this paper a comparative analysis of coating-substrate simulations applied to HFQTM forming tools is presented. When using the solution heat treatment cold die forming and quenching process, known as HFQTM, for forming of hardened aluminium alloy of ...
Leopold Jürgen, Schwarz Rene, Wohlgemuth Reiner   +2 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Numerical simulation of cold forging process to investigate folding defect in enclosed dies

Mechanics and Advanced Technologies, 2017
In the precision forging industries, improving product quality and reducing product cost are important cases. Enclosed-die forging is one of the precision forging processes.
Payman Abhari
doaj   +1 more source