Results 71 to 80 of about 3,581,165 (352)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Selected Properties of Input Stock Material for the Production of Thin-Walled Cylindrical Products by Cold Flow Forming [PDF]
Problemy Mechatroniki, 2019 This paper presents test results for the steel grade 15HGMV metallurgical purity, microstructure, method of production and effect on the mechanical performance of the input stock material for calibre 227 mm missile motor casings manufactured by cold flow
Marek BURDEK +6 more
doaj +1 more source
Modelling of self-piercing riveting with ale, cel and sph based on abaqus/explicit [PDF]
, 2017 SPR (Self-piercing riveting) is a cold forming process that is used to fasten together two or more sheets of different materials mechanically with a rivet. Also SPR emulates the results and quality of spot welding without many of the risks, such as toxic
Aihara, Hiroshi, Ishikawa, Satoshi
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Non-linear model-predictive-control for thermomechanical ring rolling [PDF]
, 2019 he authors present a new ring rolling variant that combines a semi-warm forming process of a bearing ring with controlled cooling directly followed by a cold forming process.
Brosius, Alexander +2 more
core
Quark matter nucleation in neutron stars and astrophysical implications [PDF]
, 2016 A phase of strong interacting matter with deconfined quarks is expected in the core of massive neutron stars. We investigate the quark deconfinement phase transition in cold (T = 0) and hot beta-stable hadronic matter.
Bombaci, Ignazio +3 more
core +3 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
MATEC Web of Conferences, 2016 A new cold rotary forging technology of the internal helical involute spline was presented based on an analysis of the structure of automotive starter guide cylinder. 3D rigid-plastic finite element model was employed.
Wang Ping, Dong Xiao Fei
doaj +1 more source
Research on the Production Process of High-Strength Products from Aluminum-Magnesium Alloys for their Direct Processing into Sheets Via Cold Rolling [PDF]
Archives of Metallurgy and Materials, 2019 Modern metal forming processes of non-ferrous metals, particularly aluminum and its alloys, are increasingly based on integrated technologies combining numerous operations in one process line. The subject of this paper focuses on the possibility of using
W. Ściężor +5 more
doaj +1 more source
Analysis of Innovative Incremental Cold Forming Process for the Manufacturing of Aerospace Rotating Parts [PDF]
Volume 1: Processes, 2017 Cold rotary forging is an innovative incremental metal forming process whose main characteristic is that the workpiece is only partially in contact with a conical tool, reducing therefore the required forging loads. However, in spite of many benefits of such a process, wide industrial implementation of rotary forging is not possible without proper ...
openaire +2 more sources