Results 81 to 90 of about 429,185 (305)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Cold molecules: theory, experiment, applications
, 2009 The First Book on Ultracold Molecules Cold molecules offer intriguing properties on which new operational principles can be based (e.g., quantum computing) or that may allow researchers to study a qualitatively new behavior of matter (e.g., Bose-Einstein
Stwalley, William C. +4 more
core +1 more source
A cold beam of BaOH molecules using a water-vapor seeded neon gas
New Journal of PhysicsIn this paper we report on the production and characterization of a cold beam of BaOH molecules using a cryogenic buffer-gas beam source. BaOH is a highly suitable molecule for studies of the violation of fundamental symmetries, such as the search for ...
Ties H Fikkers +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Laser cooling Rydberg molecules—a detailed study of the helium dimer
New Journal of PhysicsThe helium dimer in its metastable triplet state is a promising candidate to be the first laser-cooled homonuclear molecule. An ultracold gas of He $_2^*$ would enable a new generation of precision measurements to test quantum electrodynamics for three ...
Lucía Verdegay +4 more
doaj +1 more source
Experimental Study of Cs Isotropic and Anisotropic Polyatomic Rydberg Molecules [PDF]
, 2019 In this thesis, we investigate few-body physics and many-body physics of ultralong-range Rydberg molecules. Ultralong-range Rydberg molecules are formed through scattering processes between Rydberg electrons and ground state atoms.
Yang, Jin
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Isotopologue-selective laser cooling of molecules
New Journal of PhysicsDirect laser cooling of molecules has made significant progress in recent years. However, the selective cooling and manipulation of generic molecular samples based on their isotopic composition, which is ubiquitous in atomic laser cooling, has not yet ...
Felix Kogel +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source