New Mutations Involved in Colistin Resistance in
Colistin is used as the “last resort” to treat infections caused by multidrug-resistant Acinetobacter baumannii, which is at the top of the World Health Organization’s list of the most dangerous bacterial species that threaten human health. Unfortunately,
Bingbing Sun +5 more
doaj +1 more source
Genomic characterization of antibiotic resistant Escherichia coli isolated from domestic chickens in Pakistan [PDF]
Poultry husbandry is important for the economic health of Pakistan, but the Pakistani poultry industry is negatively impacted by infections ...
Abbas, Muhammad Athar +11 more
core +1 more source
Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis [PDF]
Background: Infections due to antibiotic-resistant bacteria are threatening modern health care. However, estimating their incidence, complications, and attributable mortality is challenging.
Abu Sin, Muna +79 more
core +6 more sources
Abstract Background Neonatal lamb mortality affects the sheep flock's productivity. In Algeria, data are very limited, making investigations quite relevant. This study aimed to determine risk factors associated with neonatal lamb mortality, describe gross and histopathological lesions on affected organs, and identify bacterial pathogens involved ...
Hayem Benmebarek +9 more
wiley +1 more source
MgrB variants in colistin-susceptible and colistin-resistant Klebsiella pneumoniae ST258
Resistance determinants of a colistin susceptible and five colistin resistant Klebsiella pneumoniae ST258 from a Hungarian outbreak were investigated. A novel MgrB variant in colistin susceptible strain was found. Elevated phoP and arn gene expressions and wild-type PmrB in all colistin resistant K. pneumoniae were detected. All strains lacked mcr-1.
Kocsis, Béla +4 more
openaire +5 more sources
ABSTRACT Cardiac tuberculosis (TB) is a rare but important extrapulmonary form of TB that often presents diagnostic challenges due to nonspecific symptoms and its ability to mimic other cardiac conditions. We report the case of a 45‐year‐old woman with end‐stage renal disease secondary to granulomatosis with polyangiitis (GPA) who presented with fever ...
Fariba Bayat +5 more
wiley +1 more source
Open conversion after aortic endograft infection. Caused by colistin-resistant, carbapenemase-producing Klebsiella pneumoniae [PDF]
A 62-year-old man presented with fever, abdominal pain, and malaise 13 months after emergency endovascular aortic repair. Computed tomographic angiograms showed a periprosthetic fluid and gas collection, so infection was diagnosed. Open conversion was
Capoccia, Laura +5 more
core +1 more source
Polymyxins are used against highly resistant Gram‐negative pathogens, and nephrotoxicity (acute kidney injury, AKI) is the major dose‐limiting adverse effect. We aimed to develop a well‐informed population pharmacokinetic/toxicodynamic (PK/TD) model using the largest polymyxin B‐treated critically ill patient population studied to inform polymyxin B ...
Patrick O. Hanafin +19 more
wiley +1 more source
Colistin-related thrombocytopenia [PDF]
To the editor,Acute thrombocytopenia occuring due to drugs is a well described but commonly misdiagnosed condition in children.
openaire +3 more sources
A proposed integrated approach for the preclinical evaluation of phage therapy in Pseudomonas infections [PDF]
Bacteriophage therapy is currently resurging as a potential complement/alternative to antibiotic treatment. However, preclinical evaluation lacks streamlined approaches.
Arabski, Michal +13 more
core +2 more sources

