Results 131 to 140 of about 97,018 (264)

Gut microbiota‐derived butyrate mediates the anticolitic effect of indigo supplementation through regulating CD4+ T cell differentiation

iMeta, EarlyView.
This study explored the effect of plant‐derived indigo supplementation on intestinal inflammation using in vivo, in vitro, and clinical sample analyses. Our results showed that indigo decreased mucosal inflammation by regulating CD4+ T cell differentiation in a gut microbiota‐dependent manner.
Yunqi Xing, Muyuan Wang, Yali Yuan, Jiayan Hu, Zhibin Wang, Zhongmei Sun, Mengyu Zheng, Lei Shi, Junxiang Li, Tangyou Mao   +9 more
wiley   +1 more source

Health benefits of algae and marine-derived bioactive metabolites for modulating ulcerative colitis symptoms

Journal of Functional Foods
Ulcerative colitis is a type of inflammatory bowel disease (IBD) that has risen around the world in recent years. Diet, lifestyle, genetics, stress, are the risk factors of ulcerative colitis.
Najmeh Oliyaei, Saghar Zekri, Aida Iraji, Alireza Oliyaei, Romina Tanideh, Nadiar M. Mussin, Amin Tamadon, Nader Tanideh   +7 more
doaj  

Self-Relaxed Joint Training: Sample Selection for Severity Estimation with Ordinal Noisy Labels [PDF]

arXiv
Severity level estimation is a crucial task in medical image diagnosis. However, accurately assigning severity class labels to individual images is very costly and challenging. Consequently, the attached labels tend to be noisy. In this paper, we propose a new framework for training with ``ordinal'' noisy labels.
arxiv  

Plant extracellular vesicles: A promising bionic medicine platform for disease treatment and drug delivery

Interdisciplinary Medicine, EarlyView.
We introduced the basic characterization and isolation methods of PEVs, reviewed the PEVs‐related articles pertaining to disease therapy and drug delivery system, and summarized the drug loading methods, storage techniques, and engineering modification strategies of the carrier, to establish a safer, more efficient and more affordable approach for ...
Jichun Yang, Yuhan Wang, Yunqian Fu, Sitong Wang, Yao Luo, Xin Cui, Chenyu Sun, Jianing Ji, Jiaxi Mo, Yang Wang, Yilin Liu, Xinghong Hu, Xiaohui Chen, Yimin Jia, Yang Luo   +14 more
wiley   +1 more source

Chinese herbal medicine‐derived extracellular vesicle‐like particles: Therapeutic potential and future research approaches

Interdisciplinary Medicine, EarlyView.
This article evaluates the therapeutic potential of extracellular vesicle‐like particles derived from Chinese herbal medicine (CHM‐EVLP) for a range of diseases. It underscores the significance of traditional Chinese medicine in the development of innovative formulations.
Ying‐qi Cao, Zheng‐ting Wu, Qi You, Yuan‐yuan Xia, Qing Zhao, Carine de Marcos Lousa, Ke‐wei Zhao   +6 more
wiley   +1 more source

Illuminating Immunity: A Systematic Review of Immune Cell Autofluorescence

Journal of Biophotonics, EarlyView.
ABSTRACT Immunophenotyping provides valuable prognostic and diagnostic information, but is technically complex and expensive. The assessment of autofluorescence is label‐free and provides complex information on cell identity. However, research on its application to immunophenotyping has been heterogenous.
Aline Knab, Caroline Giardina, Shane T. Grey, Ewa M. Goldys, Jared M. Campbell   +4 more
wiley   +1 more source

Indication‐Specific Dosing and Dose‐Evaluation Strategies in New Indications for Non‐Oncology Monoclonal Antibodies

The Journal of Clinical Pharmacology, EarlyView.
Abstract Compared to traditional small molecule drugs, monoclonal antibodies (mAbs) often display more complex pharmacokinetic (PK) and pharmacodynamic (PD) properties that may be impacted by disease‐specific factors. For mAbs in non‐oncology indications, where the same drug might be used for conditions involving different organ systems and/or having ...
Sherouk M. Tawfik, Fei Tang
wiley   +1 more source

Eosinophilic enteritis: A case for awareness among primary care physicians

Journal of General and Family Medicine, EarlyView.
In making a presumptive diagnosis of eosinophilic enteritis prompting specialist referral, primary care physicians are advised to focus on patients' medical history, medication history, clinical course, and blood tests, while bearing in mind that a definitive diagnosis of eosinophilic enteritis requires a histopathological assessment of biopsy ...
Kimitoshi Kubo, Issei Ashida, Noriko Kimura   +2 more
wiley   +1 more source

Diagnostic accuracy of pan‐enteric capsule endoscopy and magnetic resonance enterocolonography in suspected Crohn's disease

United European Gastroenterology Journal, Volume 10, Issue 9, Page 973-982, November 2022., 2022
Abstract Background and Aims Magnetic resonance enterocolonography (MREC) and pan‐enteric capsule endoscopy (CE) offers visualization of the entire gastrointestinal tract in a single examination. We examined the diagnostic accuracy of MREC and CE in patients with suspected Crohn's disease (CD).
Jacob Broder Brodersen, Torben Knudsen, Jens Kjeldsen, Mie Agerbæk Juel, Søren Rafael Rafaelsen, Michael Dam Jensen   +5 more
wiley   +1 more source

Ulcerative colitis in Nigerian children: A report of two cases and review of the literature

Nigerian Journal of Paediatrics
: Ulcerative colitis (UC) is a relapsing, idiopathic chronic inflammatory disorder of colon characterised by ulcerations of the colon with bleeding, mucosal crypt abscesses and inflammatory pseudo polyps associated with abdominal pain with tenesmus and ...
Akinyinka OO, Adepoju AA , Ashubu OF, Ogunbosi BO, Olatunji RB, Akere A, Orimadegun AE, Oluwasola AO   +7 more
doaj