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Huangqin decoction (HQD) is a Traditional Chinese Medicine formula for ulcerative colitis. However, the pharmacology and molecular mechanism of HQD on ulcerative colitis is still unclear.
Yi Wu, Xinqiao Liu, Guiwei Li
doaj +2 more sources
Ulcerative colitis is an idiopathic, chronic inflammatory disorder of the colonic mucosa, which starts in the rectum and generally extends proximally in a continuous manner through part of, or the entire, colon; however, some patients with proctitis or left-sided colitis might have a caecal patch of inflammation.
Daniel, El Fassi, Claus H, Nielsen
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Ulcerative colitis is a chronic inflammatory disease affecting the colon, and its incidence is rising worldwide. The pathogenesis is multifactorial, involving genetic predisposition, epithelial barrier defects, dysregulated immune responses, and environmental factors.
R. Ungaro+4 more
semanticscholar +3 more sources
Role of Toll-Like Receptor 5 in the Development of Ulcerative Colitis [PDF]
Inflammatory bowel disease (ulcerative colitis and Crohn’s disease) is a remitting and relapsing disease that affects millions of people worldwide. In the intestine, homeostasis between repair and signaling of the proinflammatory of the immune system is ...
A Falah Alshimerry+2 more
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Ozanimod as Induction and Maintenance Therapy for Ulcerative Colitis.
BACKGROUND Ozanimod, a selective sphingosine-1-phosphate receptor modulator, is under investigation for the treatment of inflammatory bowel disease. METHODS We conducted a phase 3, multicenter, randomized, double-blind, placebo-controlled trial of ...
W. Sandborn+15 more
semanticscholar +1 more source
The LUCID study: living with ulcerative colitis; identifying the socioeconomic burden in Europe
Background Ulcerative colitis (UC) is an inflammatory bowel disease with increasing prevalence worldwide. Current treatment strategies place considerable economic and humanistic burdens on patients.
Leonardo Ruiz-Casas+14 more
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Modern principles of conservative treatment of mild and moderate forms of ulcerative colitis
Ulcerative colitis is a chronic disease characterized by inflammation that usually begins in the rectum and diffusely spreads proximally, involving part or all of the colonic mucosa.
O. V. Golovenko
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Oral manifestation of ulcerative colitis [PDF]
Introduction Ulcerative colitis is an inflammatory bowel disease. Primary involvement is the colon. Changes in the oral cavity may occur as the part of extraintestinal manifestations of the disease.
Đuričković Aleksa+1 more
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Cholesterol sulfate, produced by hydroxysteroid sulfotransferase 2B1 (SULT2B1), is highly abundant in the intestine. Herein, we study the functional role and underlying intestinal epithelial repair mechanisms of cholesterol sulfate in ulcerative colitis.
Dongke Xu+14 more
semanticscholar +1 more source
Ulcerative colitis is a chronic, idiopathic, and inflammatory disease of the rectal and colonic mucosa, the behavior of which is of heterogeneity in individuals.
Lijie Lai+4 more
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