Results 61 to 70 of about 97,018 (264)

Gut microbiota‐stem cell niche crosstalk: A new territory for maintaining intestinal homeostasis

iMeta, Volume 1, Issue 4, December 2022., 2022
Intestinal stem cells (ISCs) are protected by their niche and are regulated by Wnt, bone morphogenetic protein, and Notch. ISCs and their relationship with intestinal microbiota provide a feasible pathway to alleviate intestinal diseases. Diverse bacteria‐related postbiotics regulate ISCs and maintain their homeostasis.
Ning Ma, Xiyue Chen, Lee J. Johnston, Xi Ma   +3 more
wiley   +1 more source

A Sequential Release Micro‐nano System for Colitis Therapy via Gut Microbiota and Immune Regulation

Angewandte Chemie, EarlyView.
The micro‐nano system achieves the sequential release of drugs in response to gut microbiota and reactive oxygen species (ROS). Inulin prebiotics restore gut microbiota balance. Selenium compounds scavenge ROS and promote macrophage polarization, while 3‐oxolithocholic acid suppresses TH17‐cell differentiation. As a multifactorial therapeutic approach,
Dongdong Zhu, Xiaocao Ma, Jingguo Wang, Tiantian Chen, Jiahui Yang, Yan Liu, Zhun Lin, Minhao Wu, Tony Y. Hu, Yuanqing Zhang   +9 more
wiley   +2 more sources

Assessment of Disease Severity and Role of Cytomegalo Virus Infection in Patients with Ulcerative Colitis [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Course of Ulcerative Colitis is characterized by intermittent flares interposed between variable periods of remission. Identification of exacerbating factors and appropriate assessment of disease activity are crucial in deciding the ...
Nobin Babu Kalappurayil, Jino Thomas, Baburajan Mankuni, Varghese Thomas   +3 more
doaj   +1 more source

Ulcerative colitis – recent and potential methods of treatment - review

Journal of Education, Health and Sport, 2023
Introduction and purpose: Ulcerative colitis (UC, colitis ulcerosa) belongs to a group of inflammatory bowel diseases of unexplained etiology. It is a diffuse nonspecific inflammation of the mucosa of the rectum or rectum and colon, leading to ...
Mikołaj Tomasik, Paweł Warzyszak, Róża Małek, Maria Milczek, Wojciech Żołyniak, Izabela Hawranik, Szymon Niski, Ziemowit Żaba, Aleksandra Lisowska, Mateusz Skrzypek   +9 more
doaj   +1 more source

Disease Severity Regression with Continuous Data Augmentation [PDF]

arXiv, 2023
Disease severity regression by a convolutional neural network (CNN) for medical images requires a sufficient number of image samples labeled with severity levels. Conditional generative adversarial network (cGAN)-based data augmentation (DA) is a possible solution, but it encounters two issues.
arxiv  

Decoding Blastocystis‐Driven Mechanisms in Gut Microbiota and Host Metabolism

Advanced Science, EarlyView.
Blastocystis, a prevalent gut microbe, interacts with the host through metabolic and immune pathways, influencing cardiometabolic health. This perspective explores its role in modulating short‐chain fatty acid production, tryptophan metabolism, and immune signaling, potentially impacting cholesterol absorption, glucose metabolism, and vascular health ...
Lei Deng, Kevin SW Tan
wiley   +1 more source

Cerbral Venous Thrombosis in Ulcerative Colitis and Review of the Literature

Canadian Journal of Gastroenterology, 1991
A 30-year-old man with an eight year history of ulcerative colitis developed left occipital headache, mental confusion, dysphasia and right-sided weakness when his bowel disease was asymptomatic.
Hugh Chaun, Jeff H Beckman, Terence G Sparling   +2 more
doaj   +1 more source

Histopathological evaluation of ulcerative colitis in colonoscopic biopsies

Journal of Pathology of Nepal, 2016
Background: Histopathologic evaluation of colonoscopic mucosal biopsy remains one of the earliest modalities of investigation in patients clinically suspected of ulcerative colitis. Pathologists should be aware of classical histomorphological features to
R Dhakhwa, HG Shrestha, IL Acharya
doaj   +1 more source

Gastrointestinal Mucosal Problems Classification with Deep Learning [PDF]

arXiv, 2023
Gastrointestinal mucosal changes can cause cancers after some years and early diagnosing them can be very useful to prevent cancers and early treatment. In this article, 8 classes of mucosal changes and anatomical landmarks including Polyps, Ulcerative Colitis, Esophagitis, Normal Z-Line, Normal Pylorus, Normal Cecum, Dyed Lifted Polyps, and Dyed ...
arxiv  

CO‐Releasing Polyoxometalates Nanozyme with Gut Mucosal Immunity and Microbiota Homeostasis Remodeling Effects for Restoring Intestinal Barrier Integrity

Advanced Science, EarlyView.
A CO‐releasing polyoxometalates nanozyme (PMC) is engineered by coordinating pentacarbonyl manganese bromide with molybdenum‐based polyoxometalates nanoclusters. PMC exhibits targeted accumulation at IBD sites, efficient ROS scavenging, and responsive CO release.
Hongyang Lu, Qiang Zhou, Jiayu Li, Shengming Xu, Li Yu, Yinci Zhu, He Zhang, Chengge Shi, Tianci Zuo, Mengzhu Xu, Mingli Su, Yanmei Zhang, Rongdang Hu, Quazi T. H. Shubhra, Hui Deng, Xiaowen Hu, Xiaojun Cai   +16 more
wiley   +1 more source