Results 61 to 70 of about 467,445 (327)

CMV in the gut: a critical review of CMV detection in the immunocompetent host with colitis. [PDF]

, 2015
As scientific techniques for the detection of cytomegalovirus (CMV) improve, we are able to detect small amounts of CMV in the mucosal wall. As clinicians, we are unsure how to interpret the results of this novel test.
Goodman, AL, Griffiths, PD, Murray, CD, Watkins, J, Webster, DP   +4 more
core   +1 more source

Ulcerative Colitis and Cytomegalovirus Infection: From A to Z.

Journal of Crohn's & Colitis, 2020
Despite multiple studies, the role of CMV infection in exacerbating the severity of inflammation in ulcerative colitis (UC) and its response to treatment remains debatable. Additionally, the optimal diagnostic tests for CMV infection in the setting of UC
F. Mourad, Jana G. Hashash, V. Kariyawasam, Rupert Leong   +3 more
semanticscholar   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

A Diagnostic Conundrum in a Newly Diagnosed Ulcerative Colitis Patient Who Presented with Pleuropericardial Effusion [PDF]

Iranian Journal of Colorectal Research, 2019
Ulcerative colitis is a chronic inflammatory disease affecting mainly the colon and presenting with diarrhea, bloody defecation andabdominal pain. Although cardiac and/or pulmonary involvement has been reported in patients with ulcerative colitis, it ...
Alpaslan Tanoglu, Omer Tekin, Tolga Duzenli, Muammer Kara, Mustafa Kaplan, Irfan Kucuk, Onur Ozari, Yusuf Yazgan   +7 more
doaj  

Intestinal barrier tightening by a cell-penetrating antibody to Bin1, a candidate target for immunotherapy of ulcerative colitis. [PDF]

, 2018
Patients afflicted with ulcerative colitis (UC) are at increased risk of colorectal cancer. While its causes are not fully understood, UC is associated with defects in colonic epithelial barriers that sustain inflammation of the colon mucosa caused by ...
Alexander, Walker, Dilbarova, Rima, Gilligan, John, Hoxha, Kevther, Kossenkov, Andrew, Mullin, James M., Prendergast, George C., Thomas, Sunil, Whittaker, Kelly   +8 more
core   +2 more sources

Ulcerative colitis: understanding its cellular pathology could provide insights into novel therapies

Journal of Inflammation, 2020
Dynamic interactions between the gastrointestinal epithelium and the mucosal immune system normally contribute to ensuring intestinal homeostasis and optimal immunosurveillance, but destabilisation of these interactions in genetically predisposed ...
Amandip Kaur, P. Goggolidou
semanticscholar   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

A Parasite That Should not be Neglected in Patients with Ulcerative Colitis: Entamoeba histolytica

Türkiye Parazitoloji Dergisi
Objective: To determine the prevalence of amoebiasis, which has been neglected in recent years according to the World Health Organization, in ulcerative colitis patients and investigate the relationship between amoebiasis and ulcerative colitis. Methods:
Murat Soylu, Abdurrahman Ekici, Selahattin Aydemir, Şehriban Yürektürk, Önder Akkaş   +4 more
doaj   +1 more source

Histopathological evaluation of ulcerative colitis in colonoscopic biopsies

Journal of Pathology of Nepal, 2016
Background: Histopathologic evaluation of colonoscopic mucosal biopsy remains one of the earliest modalities of investigation in patients clinically suspected of ulcerative colitis. Pathologists should be aware of classical histomorphological features to
R Dhakhwa, HG Shrestha, IL Acharya
doaj   +1 more source

Ulcerative colitis: focus on colonic mucosal resistance

Бюллетень сибирской медицины, 2022
In recent decades, following cooperation between scientists in various specialties, new unique data on the pathogenesis of ulcerative colitis have been obtained.
M. A. Livzan, G. R. Bicbavova, A. E. Romanyuk   +2 more
doaj   +1 more source