Results 61 to 70 of about 461,819 (327)

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

A Diagnostic Conundrum in a Newly Diagnosed Ulcerative Colitis Patient Who Presented with Pleuropericardial Effusion [PDF]

Iranian Journal of Colorectal Research, 2019
Ulcerative colitis is a chronic inflammatory disease affecting mainly the colon and presenting with diarrhea, bloody defecation andabdominal pain. Although cardiac and/or pulmonary involvement has been reported in patients with ulcerative colitis, it ...
Alpaslan Tanoglu, Omer Tekin, Tolga Duzenli, Muammer Kara, Mustafa Kaplan, Irfan Kucuk, Onur Ozari, Yusuf Yazgan   +7 more
doaj  

Development of colon cancer after liver transplantation for primary sclerosing cholangitis associated with ulcerative colitis [PDF]

, 1990
Between February 26, 1981, and July 30, 1987, 36 patients underwent orthotopic liver transplantation for primary sclerosing cholangitis associated with ulcerative colitis.
Higashi, H, Kakizoe, S, Marsh, JW, Starzi, TE, Tzakis, A, Yanaga, K   +5 more
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

A Parasite That Should not be Neglected in Patients with Ulcerative Colitis: Entamoeba histolytica

Türkiye Parazitoloji Dergisi
Objective: To determine the prevalence of amoebiasis, which has been neglected in recent years according to the World Health Organization, in ulcerative colitis patients and investigate the relationship between amoebiasis and ulcerative colitis. Methods:
Murat Soylu, Abdurrahman Ekici, Selahattin Aydemir, Şehriban Yürektürk, Önder Akkaş   +4 more
doaj   +1 more source

Histopathological evaluation of ulcerative colitis in colonoscopic biopsies

Journal of Pathology of Nepal, 2016
Background: Histopathologic evaluation of colonoscopic mucosal biopsy remains one of the earliest modalities of investigation in patients clinically suspected of ulcerative colitis. Pathologists should be aware of classical histomorphological features to
R Dhakhwa, HG Shrestha, IL Acharya
doaj   +1 more source

Ulcerative colitis: focus on colonic mucosal resistance

Бюллетень сибирской медицины, 2022
In recent decades, following cooperation between scientists in various specialties, new unique data on the pathogenesis of ulcerative colitis have been obtained.
M. A. Livzan, G. R. Bicbavova, A. E. Romanyuk   +2 more
doaj   +1 more source

Myeloperoxidase Luminol Reaction – A Novel Faecal Assay for Predicting Colonoscopy Findings in Patients with Ulcerative Colitis: A Pilot Cross‐Sectional Clinical Study

Advanced Healthcare Materials, EarlyView.
Can luminol detect faecal inflammation? This study explores the development and optimisation of a rapid novel assay ‐ Myeloperoxidase Luminol Reaction (MPOLR) for the detection of faecal myeloperoxidase activity. This simple and rapid luminol‐based approach competes with clinically validated faecal biomarkers in predicting endoscopic findings in ...
Viraj Kariyawasam, Taylor Davis, Mark Ghali, David Tejcek, Thomas R O'Neil, Ella Verley, Matthew Griffiths, Miguel Campos, Ingrid Bonney, Andrew C. Bulmer, Yogambha Ramaswamy, Nikola Mitrev, Crispin Corte, Paul K. Witting, Belal Chami   +14 more
wiley   +1 more source

Clinical practice and outcome of patients with elderly‐onset ulcerative colitis: Insights from a nationwide claims database study in Japan

JGH Open
Background and Aim The number of older patients with ulcerative colitis is increasing; however, limited data exist regarding the differences between elderly‐ and non‐elderly‐onset ulcerative colitis.
Rintaro Moroi, Yoichi Kakuta, Hiroshi Nagai, Yusuke Shimoyama, Takeo Naito, Hisashi Shiga, Yoshitaka Kinouchi, Atsushi Masamune   +7 more
doaj   +1 more source

Assessment of Circulating MicroRNAs for the Diagnosis and Disease Activity Evaluation in Patients with Ulcerative Colitis by Using the Nanostring Technology [PDF]

, 2015
Background: Clinical decision and patient care management in inflammatory bowel diseases is largely based on the assessment of clinical symptoms, while the biomarkers currently in use poorly reflect the actual disease activity.
Alexandra Touroutoglou, Angelos Oikonomopoulos, Baltimore, Baumgart, Cho, Christos Polytarchou, CramaBohbouth, Creemers, Daniel W. Hommes, Dimitrios Iliopoulos, Georgios Koukos, Guo, Hatziapostolou, Iskandar, Kappelman, Kosaka, Kumar, Lewis, Linskens, Loftus, Mitchell, Pepys, Saverymuttu, Schoepfer, Schroeder, Schwarzenbach, Solem, Solem, Swapna Mahurkar, van Rooij, Wang, Xavier   +31 more
core   +1 more source