Results 71 to 80 of about 114,848 (257)

Ulcerative colitis in infancy

Saudi Journal of Gastroenterology, 2011
Ulcerative colitis (UC) is a chronic idiopathic inflammatory disorder of colon. Frequency of UC is gradually increasing over few years worldwide. Prevalence is 35 to 100/100,000 people in USA, 1% of them are infants. UC develops in a genetically predisposed individual with altered intestinal immune response. An eight-month-old girl presented with loose
Md Rukunuzzaman, A. S. M. Bazlul Karim
openaire   +3 more sources

Oral Prebiotic Polysaccharide Hydrogels Sustaining Colon Antibody Release Alleviate Inflammatory Bowel Disease

Advanced Science, EarlyView.
An orally administered prebiotic polysaccharide hydrogel (predaGel) based on inulin and alginate‐dopamine is stable in the stomach, adheres to the intestine, and degrades slowly in the colon. It enables site‐specific delivery of anti‐TNF‐α and anti‐IL‐12/23 antibodies, scavenges reactive oxygen species, and remodels gut microbiota, offering effective ...
Xinyi Dong, Huan He, Li Cao, Fenghua Meng, Zhiyuan Zhong   +4 more
wiley   +1 more source

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

Advanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang, Lintao Dan, Xin Xiang, Xixian Ruan, Shuai Yuan, Jialu Yao, Jiawei Geng, Jonas F. Ludvigsson, Tian Fu, Candida Abreu, Laurent Peyrin‐Biroulet, Xue Li, Yi Xiao, Fernando Magro, Xiaoyan Wang, Jing Sun, Jie Chen   +16 more
wiley   +1 more source

Correction to: The LUCID study: living with ulcerative colitis; identifying the socioeconomic burden in Europe

BMC Gastroenterology, 2021
Leonardo Ruiz-Casas, Jonathan Evans, Alison Rose, Gabriel Ghizzi Pedra, Alan Lobo, Alan Finnegan, Bu Hayee, Laurent Peyrin-Biroulet, Andreas Sturm, Johan Burisch, Helen Terry, Luisa Avedano, Seb Tucknott, Gionata Fiorino, Jimmy Limdi   +14 more
doaj   +1 more source

Cerbral Venous Thrombosis in Ulcerative Colitis and Review of the Literature

Canadian Journal of Gastroenterology, 1991
A 30-year-old man with an eight year history of ulcerative colitis developed left occipital headache, mental confusion, dysphasia and right-sided weakness when his bowel disease was asymptomatic.
Hugh Chaun, Jeff H Beckman, Terence G Sparling   +2 more
doaj   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Identification of symptom domains in ulcerative colitis that occur frequently during flares and are responsive to changes in disease activity

Health and Quality of Life Outcomes, 2008
Background Ulcerative colitis disease activity is determined by measuring symptoms and signs. Our aim was to determine which symptom domains are frequent and responsive to change in the evaluation of disease activity, which are those defined by three ...
Wang Sijian, Zimmermann Ellen M, Dave Maneesh, Wren Patricia A, Khan Tahira, Waljee Akbar K, Joyce Joel C, Zhu Ji, Higgins Peter DR   +8 more
doaj   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

The Compartive Study of Prevalence of Ulcerative Colitis in General Population with MS Patients

مجله دانشکده پزشکی اصفهان, 2011
Background: Multiple sclerosis and ulcerative colitis are two chronic and disabling disease that cause many problems to patients. Until now there is not a good study to determine relation and similarity between this disease.
Masood Etemadifar, Ahmad Chitsaz, Maryam Mollabashi, Azam Moradi, Mehdi Teimouri, Shirin Ashkbosi   +5 more
doaj  

Oral Delivery Systems for Food‐Derived Bioactive Peptides: Enhancing Stability, Bioavailability, and Health Benefits

Advanced Science, EarlyView.
Advanced delivery systems—including nanoparticles, nanoemulsions, liposomes, and hydrogels—protect food‐derived bioactive peptides from gastrointestinal degradation and bitterness. These systems enable pH‐responsive release, enhance intestinal absorption, and improve therapeutic efficacy against oxidative stress, metabolic disorders, cancer, and ...
Yu Xu, Fan Li, Runan Zhao, Tao Shu, Weihong Min, Bei‐Wei Zhu   +5 more
wiley   +1 more source