Results 71 to 80 of about 97,018 (264)

The Encapsulation Strategies for Targeted Delivery of Probiotics in Preventing and Treating Colorectal Cancer: A Review

Advanced Science, EarlyView.
This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong, Jin Jiang, Muhammad Hussain, Haoxuan Zhang, Ling Chen, Rongfa Guan   +5 more
wiley   +1 more source

Smoking and nicotine in inflammatory bowel disease: good or bad for cytokines?

Mediators of Inflammation, 1998
Smoking has either a beneficial or harmful effect on the course and recurrence of ulcerative colitis and Crohn's disease respectively. Transdermal application of nicotine had similar effects in ulcerative colitis and therefore was considered to be an ...
F. J. Zijlstra
doaj   +1 more source

ULCERATIVE COLITIS IN CHILDREN [PDF]

Romanian Journal of Pediatrics, 2009
Chronic nonspecific ulcerative colitis remaine a disease of unkown etiology, although much new information continues to be gleaned from basic research and clinical trials. In most instances, ulcerative colitis respond to medical therapy.
Florea Iordăchescu
doaj   +1 more source

Functional Materials Targeted Regulation of Gasdermins: From Fundamentals to Functionalities and Applications

Advanced Science, EarlyView.
Targeted regulation of pyroptosis to modulate the immune landscape is a novel design strategy for cancer immunotherapy and anti‐inflammatory treatment. Pyroptosis, as a double‐edged sword, underscores the importance of optimizing the design strategy of functional materials and appropriately activating pyroptosis for the effective treatment of diseases.
Luyao Tian, Shuo Piao, Xia Li, Lanping Guo, Luqi Huang, Wenyuan Gao   +5 more
wiley   +1 more source

The role of the Notch signalling pathway in the pathogenesis of ulcerative colitis: from the perspective of intestinal mucosal barrier

Frontiers in Medicine
Ulcerative colitis is a common digestive disorder worldwide, with increasing incidence in recent years. It is an urgent problem to be solved, as it seriously affects and threatens the health and life of the global population.
Hang Ning, Jiemin Liu, Jiaqian Tan, Mengni Yi, Xiaoyuan Lin   +4 more
doaj   +1 more source

Prognostic value of surgical treatment in elderly patients with ulcerative colitis‐associated colorectal cancer: A subanalysis of a nationwide Japanese multicenter study

Annals of Gastroenterological Surgery, EarlyView.
Our study examined the characteristics of elderly patients diagnosed with ulcerative colitis‐associated colorectal cancer. We showed that factors associated with aggressive tumor characteristics played a significant role in recurrence risk in the nonelderly patients, but not in the elderly patients.
Kinuko Nagayoshi, Yusuke Mizuuchi, Masafumi Nakamura, Koji Okabayashi, Motoi Uchino, Hiroki Ikeuchi, Tatsuki Noguchi, Soichiro Ishihara, Yoichi Ajioka, Kenichi Sugihara, from the Study Group for Inflammatory Bowel Disease Associated Intestinal Cancers by the Japanese Society for Cancer of the Colon and Rectum   +10 more
wiley   +1 more source

Molecular mechanism of Huaihuasan in treatment of ulcerative colitis based on network pharmacology and molecular docking

Phytomedicine Plus, 2021
Background: Huaihuasan (HHS) is a Traditional Chinese Medicine formula for ulcerative colitis (UC). However, the pharmacology and molecular mechanism of HHS on ulcerative colitis still unclear.
Yi Wu, Xiaokun Yang, Guiwei Li, Xinqiao Liu   +3 more
doaj  

Reoperative pouch surgery for suspected Crohn's‐related complications aided by biologic coverage: Early experience from an inflammatory bowel disease center

Annals of Gastroenterological Surgery, EarlyView.
This paper demonstrates that revisional/redo ileal pouch anal anastomosis (IPAA) surgery with concurrent biologic therapy provides a viable, stoma‐free alternative for patients with Crohn's disease‐like complications, showing a high functioning pouch rate and expanding options for managing pouch failure.
Mehmet Gulmez, Daniel J. Wong, Ariela K. Holmer, Eren Esen, Shannon Chang, Arman Erkan, David Hudesman, Andre da Luz Moreira, Feza H. Remzi   +8 more
wiley   +1 more source

Estimating Model Performance on External Samples from Their Limited Statistical Characteristics [PDF]

Proceedings of the Conference on Health, Inference, and Learning. PMLR, 2022, p. 48-62, 2022
Methods that address data shifts usually assume full access to multiple datasets. In the healthcare domain, however, privacy-preserving regulations as well as commercial interests limit data availability and, as a result, researchers can typically study only a small number of datasets.
arxiv  

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

Aggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai, Yun Su, Cong Hu, Zehong Peng, Wei Xue, Liang Dong, Tony Y. Hu   +6 more
wiley   +1 more source