Results 21 to 30 of about 302,337 (268)

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Sexual and reproductive health considerations in the care of young adults with inflammatory bowel disease: A multidisciplinary conversation

Health Care Transitions
The effects of inflammatory bowel disease (IBD) and the medications used to treat it on sexual and reproductive health can be significant, impacting the quality of life of patients across gender identities.
Sydney Reed, Amy K. Bugwadia, Sneha Dave, Hannah E. Wilson, Prathikka Ramesh, Hilary K. Michel   +5 more
doaj   +1 more source

Phenolic Compounds Impact on Rheumatoid Arthritis, Inflammatory Bowel Disease and Microbiota Modulation

Pharmaceutics, 2021
Non-communicable chronic diseases (NCDs) are nowadays the principal cause of death, especially in most industrialized nations. These illnesses have increased exponentially with the consumption of diets very high in fat and sugar, not to mention stress ...
Rosa Direito, João Rocha, Bruno Sepodes, Maria Eduardo-Figueira   +3 more
doaj   +1 more source

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

Advanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava, Alireza Rafieerad, Weiang Yan, Keshav Narayan Alagarsamy, Qingdong Guan, Leena Regi Saleth, Michel Aliani, Sanjiv Dhingra   +7 more
wiley   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Providing LGBTQ+ affirming care to young adults with inflammatory bowel diseases

Health Care Transitions
Creating an affirming care environment for young adults with IBD in the LGBTQ+ community is an essential part of inflammatory bowel disease (IBD) care.
Cade Johnson, Sneha Dave, Sydney Reed, Victor Chedid, Lucy Laube, Laura Targownik   +5 more
doaj   +1 more source

An updated review of gastrointestinal toxicity induced by PD-1 inhibitors: from mechanisms to management

Frontiers in Immunology, 2023
PD-1 inhibitors, as one of commonly used immune checkpoint inhibitors, enable T-cell activation and prevent immune escape by blocking the PD-1/PD-L1 signaling pathway.
Yiyu Cheng, Fangmei Ling, Junrong Li, Yidong Chen, Mingyang Xu, Shuang Li, Liangru Zhu   +6 more
doaj   +1 more source

Tailored Xenogeneic‐Free Polymer Surface Promotes Dynamic Migration of Intestinal Stem Cells

Advanced Materials, EarlyView.
This study introduces a PoLymer‐coated Ultra‐stable Surface (PLUS), a nitrogen plasma‐treated poly(ethyleneglycoldimethacrylate), as a stable xenogeneic‐free platform for intestinal stem cell culture. PLUS enhances cell attachment, supports actin‐driven migration, and retains functionality after 3 years of storage. Promoting cytoskeletal reorganization,
Seonghyeon Park, Sang Yu Sun, Jin Gyeong Son, Sun Young Lee, Hyun Kyong Shon, Ohman Kwon, Minseok Lee, Keonwoo Choi, Jemin Yeun, Sung Hyun Yoon, Minkyung Kim, Mi‐Young Son, Tae Geol Lee, Sung Gap Im   +13 more
wiley   +1 more source

Use of Biomarkers of Inflammation in the Differentiation of Iron Deficiency and Anaemia—Lessons from Inflammatory Bowel Disease

Diagnostics
Iron deficiency and iron deficiency anaemia are common in inflammatory bowel disease (IBD), to the detriment of the patients’ quality of life. Since ferritin, as an acute-phase protein (APP), has limited diagnostic value in IBD, concurrent assessment of ...
Karima Farrag, Aysegül Aksan, Valëza Ademaj-Kospiri, Eleni Leventi, Jürgen Stein   +4 more
doaj   +1 more source

Analysis of Clinical and Histopathological Findings in Microscopic Colitis

Türk Patoloji Dergisi, 2022
Objective: Microscopic colitis is a chronic inflammatory disorder characterized by a triad of chronic diarrhea, endoscopy without significant abnormality, and distinct histopathological features. Histopathologically, microscopic colitis is divided into 3
Gozde TOPEL, Ebru CAKIR, Ilgin AYDIN, Fatma Husniye DILEK, Aysegul AKDER SARI   +4 more
doaj   +1 more source