Results 21 to 30 of about 433,882 (351)
Infliximab for induction and maintenance therapy for ulcerative colitis.
BACKGROUND Infliximab, a chimeric monoclonal antibody directed against tumor necrosis factor alpha, is an established treatment for Crohn's disease but not ulcerative colitis. METHODS Two randomized, double-blind, placebo-controlled studies--the Active
P. Rutgeerts+13 more
semanticscholar +1 more source
ACG Clinical Guideline: Ulcerative Colitis in Adults
Ulcerative colitis (UC) is an idiopathic inflammatory disorder. These guidelines indicate the preferred approach to the management of adults with UC and represent the official practice recommendations of the American College of Gastroenterology.
D. Rubin+4 more
semanticscholar +1 more source
Ulcerative colitis: an update.
Ulcerative colitis is a relapsing and remitting disease that is increasing in incidence and prevalence. Management aims to achieve rapid resolution of symptoms, mucosal healing and improvement in a patient's quality of life.
J. Segal, J. LeBlanc, A. Hart
semanticscholar +1 more source
Background and Aims The present systematic review and meta-analysis was designed to estimate the safety and effectiveness of ustekinumab in the treatment of Crohn disease (CD) in clinical trials and observational studies.
Mohammed Assem Khorshid+2 more
doaj +1 more source
Microscopic colitis is a frequent cause of chronic watery diarrhea, especially in older persons. Common associated symptoms include abdominal pain, arthralgias, and weight loss. The incidence of microscopic colitis had been increasing, although more recent studies have shown a stabilization of incidence rates.
openaire +3 more sources
Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis.
BACKGROUND The efficacy of ustekinumab, an antagonist of the p40 subunit of interleukin-12 and interleukin-23, as induction and maintenance therapy in patients with ulcerative colitis is unknown.
B. Sands+15 more
semanticscholar +1 more source
By colitis one understands a disease characterised anatomically by an ulcerative or membranous affection of the large intestine, and signalised clinically by acute sanguinolent or muco-purulent diarrhóa, plus pyrexia and prostration.
openaire +1 more source
Background: A 66-year-old-woman, undergoing chemotherapy for recently diagnosed acute myeloid leukemia developed increasing abdominal pain over a period of several days. Laboratory results showed, apart from severe neutropenia, increasing infection parameters.
Talebian, A.+6 more
openaire +6 more sources
Background & Aims The pathogenesis of immune checkpoint inhibitor (ICI)–colitis remains incompletely understood. We sought to identify key cellular drivers of ICI-colitis and their similarities to idiopathic ulcerative colitis, and to determine potential
S. Sasson+25 more
semanticscholar +1 more source