Results 41 to 50 of about 580,991 (316)

Beneficial effect of voluntary exercise on experimental colitis in mice fed a high-fat diet : the role of irisin, adiponectin and proinflammatory biomarkers [PDF]

open access: yes, 2017
Inflammatory bowel diseases (IBDs) are a heterogeneous group of disorders exhibited by two major phenotypic forms: Crohn‘s disease and ulcerative colitis.
Bilski, Jan   +10 more
core   +1 more source

Safety and Efficacy of Ustekinumab in the Treatment of Crohn Disease: A Systematic Review and Meta-analysis

open access: yesJournal of Coloproctology, 2022
Background and Aims The present systematic review and meta-analysis was designed to estimate the safety and effectiveness of ustekinumab in the treatment of Crohn disease (CD) in clinical trials and observational studies.
Mohammed Assem Khorshid   +2 more
doaj   +1 more source

The risk of colorectal cancer in ulcerative colitis: a meta-analysis

open access: yesGut, 2001
BACKGROUND AND AIMS Controversy surrounds the risk of colorectal cancer (CRC) in ulcerative colitis (UC). Many studies have investigated this risk and reported widely varying rates.
J. Eaden, K. Abrams, J. Mayberry
semanticscholar   +1 more source

Dimethyl Fumarate Alleviates Dextran Sulfate Sodium-Induced Colitis, through the Activation of Nrf2-Mediated Antioxidant and Anti-inflammatory Pathways. [PDF]

open access: yes, 2020
Oxidative stress and chronic inflammation play critical roles in the pathogenesis of ulcerative colitis (UC) and inflammatory bowel diseases (IBD). A previous study has demonstrated that dimethyl fumarate (DMF) protects mice from dextran sulfate sodium ...
Farzaneh, Ted   +8 more
core   +2 more sources

Class Distance Weighted Cross-Entropy Loss for Ulcerative Colitis Severity Estimation [PDF]

open access: yesarXiv, 2022
In scoring systems used to measure the endoscopic activity of ulcerative colitis, such as Mayo endoscopic score or Ulcerative Colitis Endoscopic Index Severity, levels increase with severity of the disease activity. Such relative ranking among the scores makes it an ordinal regression problem.
arxiv  

Microscopic Colitis [PDF]

open access: yesClinics in Geriatric Medicine, 2003
Microscopic colitis is a frequent cause of chronic watery diarrhea, especially in older persons. Common associated symptoms include abdominal pain, arthralgias, and weight loss. The incidence of microscopic colitis had been increasing, although more recent studies have shown a stabilization of incidence rates.
openaire   +3 more sources

Hyaluronic acid-bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome, and immune responses in colitis.

open access: yesNature Materials, 2019
While conventional approaches for inflammatory bowel diseases mainly focus on suppressing hyperactive immune responses, it remains unclear how to address disrupted intestinal barriers, dysbiosis of the gut commensal microbiota and dysregulated mucosal ...
Yonghyun Lee   +5 more
semanticscholar   +1 more source

Interferon-Gamma–Producing CD8+ Tissue Resident Memory T Cells Are a Targetable Hallmark of Immune Checkpoint Inhibitor–Colitis

open access: yesGastroenterology, 2021
Background & Aims The pathogenesis of immune checkpoint inhibitor (ICI)–colitis remains incompletely understood. We sought to identify key cellular drivers of ICI-colitis and their similarities to idiopathic ulcerative colitis, and to determine potential
S. Sasson   +25 more
semanticscholar   +1 more source

Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis [PDF]

open access: yes, 2019
Inflammatory diseases of the gastrointestinal tract are emerging as a global problem with increased evidence and prevalence in numerous countries. A dysregulated sphingolipid metabolism occurs in patients with ulcerative colitis and is discussed to ...
Becker, Katrin A.   +9 more
core   +1 more source

Colitis [PDF]

open access: yesJournal of Mental Science, 1898
By colitis one understands a disease characterised anatomically by an ulcerative or membranous affection of the large intestine, and signalised clinically by acute sanguinolent or muco-purulent diarrhóa, plus pyrexia and prostration.
openaire   +1 more source

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