Results 71 to 80 of about 623,983 (417)

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Multi‐omics analyses reveal the interaction between colonic microbiota and host in Min and Yorkshire pigs

Animal Research and One Health, EarlyView., 2023
In the present study, we created the weight gain models with Min and Yorkshire pigs and conducted the metagenomics and metabolomics of colon contents and transcriptomics of colon tissue. Further, we revealed the characteristics and functions of the colonic microbiota in Min and Yorkshire pigs and analyzed their interactions with the host. Overall, this
Xiaoyu Huang, Huihui Li, Feng Cheng, Ligang Wang, Guoqing Cao, Lixian Wang, Lijun Shi   +6 more
wiley   +1 more source

Serum antibodies in first-degree relatives of patients with IBD: A marker of disease susceptibility? A follow-up pilot-study after 7 years [PDF]

, 2005
Introduction: Various disease-specific serum antibodies were described in patients with inflammatory bowel disease and their yet healthy first-degree relatives.
Bansi DS, C. Brückl, C. Folwaczny, Cambridge G, Colombel JF, Folwaczny C, Folwaczny C, Folwaczny C, Folwaczny C, Glas J, H.C. Hollay, H.P. Török, Hoffman IE, J. Glas, Klebl FH, Klebl FH, L. Tonenchi, Lombardi G, M. Folwaczny, M. Osthoff, Quinton JF, R. Gruber, Ruemmele FM, Seibold F, Seibold F, Shanahan F, Shanahan F, T. Mussack, Torok HP, Torok HP   +29 more
core   +5 more sources

Ulcerative Colitis Mayo Endoscopic Scoring Classification with Active Learning and Generative Data Augmentation [PDF]

arXiv, 2023
Endoscopic imaging is commonly used to diagnose Ulcerative Colitis (UC) and classify its severity. It has been shown that deep learning based methods are effective in automated analysis of these images and can potentially be used to aid medical doctors.
arxiv  

The molecular landscape of colitis-associated carcinogenesis [PDF]

, 2016
In spite of the well-established histopathological phenotyping of IBD-associated preneoplastic and neoplastic lesions, their molecular landscape remains to be fully elucidated. Several studies have pinpointed the initiating role of longstanding/relapsing
D'Inca', Renata, Fassan, Matteo, Mescoli, Claudia, Michielan, Andrea, Rugge, Massimo, Saraggi, Deborah, Scarpa, Marco, Valeri, Nicola   +7 more
core   +1 more source

Dysplasia and Colitis [PDF]

Canadian Journal of Gastroenterology, 2009
The issue of dysplasia within the setting of chronic colitis is rapidly evolving, and more aggressive endoscopic management and surveillance is clearly being suggested in selected cases (1–3). With the advent of more effective therapies such as tumour necrosis factor inhibitors, it has been suggested that some patients are likely to be managed with ...
Robert Enns, Brian Bressler
openaire   +3 more sources

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Use of Biomarkers of Inflammation in the Differentiation of Iron Deficiency and Anaemia—Lessons from Inflammatory Bowel Disease

Diagnostics
Iron deficiency and iron deficiency anaemia are common in inflammatory bowel disease (IBD), to the detriment of the patients’ quality of life. Since ferritin, as an acute-phase protein (APP), has limited diagnostic value in IBD, concurrent assessment of ...
Karima Farrag, Aysegül Aksan, Valëza Ademaj-Kospiri, Eleni Leventi, Jürgen Stein   +4 more
doaj   +1 more source

SlpB Protein Enhances the Probiotic Potential of L. lactis NCDO 2118 in Colitis Mice Model

Frontiers in Pharmacology, 2021
Bacteria used in the production of fermented food products have been investigated for their potential role as modulators of inflammation in gastrointestinal tract disorders such as inflammatory bowel diseases (IBD) that cause irreversible changes in the ...
Giovanna A. Belo, Bárbara F. Cordeiro, Emiliano R. Oliveira, Marina P. Braga, Sara H. da Silva, Bruno G. Costa, Flaviano dos S. Martins, Gwénaël Jan, Yves Le Loir, Alfonso Gala-García, Alfonso Gala-García, Enio Ferreira, Vasco Azevedo, Fillipe L. R. do Carmo, Fillipe L. R. do Carmo   +14 more
doaj   +1 more source

Identification of biomarkers of colitis to monitor effects of dietary omega-3 polyunsaturated fatty acids in the interleukin-10 gene-deficient mouse model of inflammatory bowel diseases : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Nutritional Science at Massey University, Manawatū, New Zealand [PDF]

, 2016
Inflammatory bowel diseases (IBD) are characterised by chronic inflammation of the gastrointestinal tract including the colon (colitis). Increased dietary intake of salmon, which is rich in eicosapentaenoic acid (EPA), was well tolerated by IBD patients,
Berger, Nadja
core