Results 81 to 90 of about 199,144 (206)

Survey of demographic characteristics and diagnostic features of Ulcerative colitis patients in Ardabil province [PDF]

Introduction :Ulcerative colitis is an inflammatory disease of gastrointestinal tract. Although, determination of epidemiological characteristics and risk factors and clinical features and treatment, can lead to management of this disease, we therefore ...
ادیبان, وحید, اعظمی, احد, یزدانبد, عباس   +2 more
core  

Reoperative pouch surgery for suspected Crohn's‐related complications aided by biologic coverage: Early experience from an inflammatory bowel disease center

Annals of Gastroenterological Surgery, EarlyView.
This paper demonstrates that revisional/redo ileal pouch anal anastomosis (IPAA) surgery with concurrent biologic therapy provides a viable, stoma‐free alternative for patients with Crohn's disease‐like complications, showing a high functioning pouch rate and expanding options for managing pouch failure.
Mehmet Gulmez, Daniel J. Wong, Ariela K. Holmer, Eren Esen, Shannon Chang, Arman Erkan, David Hudesman, Andre da Luz Moreira, Feza H. Remzi   +8 more
wiley   +1 more source

Clinical and Economic Insights Into Surgery for Colonic Diverticular Perforation: A Long‐Term Observational Cohort Study

Annals of Gastroenterological Surgery, EarlyView.
The sigmoid colon was the most common perforation site among patients with colonic diverticular perforation. The patients' conditions, length of hospital stay, and hospitalization cost were significantly worse in left‐sided colon diverticular perforation than in right‐sided colon diverticular perforation. The clinical characteristics differed according
Minoru Fujita, Noriaki Manabe, Munenori Takaoka, Masaharu Higashida, Hideo Matsumoto, Atsushi Urakami, Tomoki Yamatsuji, Tomio Ueno, Jiro Hata, Ken Haruma, Collaborators, Hisako Kubota, Jiro Hayashi, Masaki Matsubara, Takako Konishi, Emiko Bukeo, Tomohiro Tanikawa, Jun Nakamura, Mitsuhiko Suehiro, Maki Ayaki, Takahisa Murao, Kazuhiro Yoshida, Takashi Akiyama, Katsuya Kato, Hirofumi Kawamoto, Tomoari Kamada, Akiko Shiotani, Minoru Haisa, Yoshio Naomoto, Toshihiro Hirai   +29 more
wiley   +1 more source

Multiple Sampling Capsule Robot for Studying Gut Microbiome

Advanced Intelligent Systems, EarlyView.
A multiple sampling capsule robot (MSCR) is developed for longitudinal gut microbiome analysis. Employing electromagnetic field control, the MSCR can locomote actively, precisely align the selected channel, and collect up to six microbiome samples with minimal cross‐contamination.
Sanghyeon Park, Manh Cuong Hoang, Jayoung Kim, Sukho Park   +3 more
wiley   +1 more source

Checkpoint inhibitors: What gastroenterologists need to know. [PDF]

, 2018
Checkpoint inhibitors are increasingly being used in clinical practice. They can cause various gastrointestinal, hepatic and pancreatic side effects. As these side effects can be serious, appropriate management is essential.
Ahmed, Monjur
core   +1 more source

Hierarchical Superposition Framework Reveals the Complex Effects of Natural Medicine Formulas

Advanced Intelligent Systems, EarlyView.
A novel hierarchical superposition pharmacological model incorporates the principle of hierarchical structures from physics to simulate the spatiotemporal dynamics of drug combinations, to elucidate the universal law underlying drug combination effects. By modeling cross‐level causal transmission and attenuation, it advances beyond traditional additive
Weifeng Liang, Dingsi Xiang, Shengli Mi, Jiajun Huang   +3 more
wiley   +1 more source

Application of humanized mice in the safety experiments of antibody drugs

Animal Models and Experimental Medicine, EarlyView.
The graphical abstract of this review highlights the critical role of humanized mice in the safety evaluation of antibody drugs. First, the inherent immunogenicity of antibody drugs can lead to the production of antidrug antibodies and hypersensitivity reactions on repeated administration.
Zhimin Sun, Mengyun Gu, Zixuan Yang, Lei Shi, Liyuan Zhao, Minhui Zheng, Yan Wang, Wei Zhang, Kexin Han, Naping Tang   +9 more
wiley   +1 more source

Yunweiling alleviates functional constipation: integrating network pharmacology and experimental study

Animal Models and Experimental Medicine, EarlyView.
In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang, Wei Li, Weiwen Zheng, Jinwen Liu, Nuonan She, Xia Chen, Weibo Wen   +6 more
wiley   +1 more source

Dietary Qiwenghuangbo powder–enriched Limosilactobacillus reuteri protects the intestinal epithelium and alleviates inflammation via a strain‐specific mechanism

Animal Models and Experimental Medicine, EarlyView.
Dietary Qiwenghuangbo powder improved growth performance and intestinal health of weaned piglets, as well as altered microbiota composition as significant enrichment of Limosilactobacillus reuteri. Furthermore, out of three isolated L. reuteri, two strains could alleviate pathogen infection and intestinal inflammation in the colitis models induced by ...
Qian Xu, Lei Xue, Zhenhua Wu, Shuaishuai Kang, Jia Li, Yifan Wu, Yujun Wu, Jinbiao Zhao, Rujuan Wu, Huiyuan Lv, Junjun Wang, Dandan Han   +11 more
wiley   +1 more source

Extracellular Vesicles in Calcium Oxalate Nephrolithiasis: Emerging Biomarkers and Therapeutic Potential

Advanced NanoBiomed Research, EarlyView.
Kidney stones cause significant pain and healthcare costs. Current prediction, diagnosis, and treatment options are limited. Extracellular vesicles (EVs), rich in proteins, lipids, and nucleic acids, offer a promising solution. This review explores the roles of EVs in kidney stone management, highlighting their potential as biomarkers and therapeutic ...
Wang Zhu, Xu Changzhi, Deng Qiong, Liang Hui   +3 more
wiley   +1 more source