Results 61 to 70 of about 36,686 (299)
Humanities & Social Sciences CommunicationsQuestions abound over how universities should teach and prepare the next generation of researchers to confront current and future wicked problems. With so much focus on curriculum and training, it is crucial that we step back and reflect on higher ...
Michael Carolan
doaj +1 more source
Hybrid Continuum Robot Designs and Architectures for Healthcare Applications
Advanced Robotics Research, EarlyView.Hybrid continuum robots represent an emerging class of flexible manipulators that blend materials, structures, and actuation concepts from the established fields of soft and continuum robotics. This review introduces an accessible framework to distinguish key hybridization approaches, surveys current designs aimed at complex clinical applications, and ...
Burak Ozdemir +4 more
wiley +1 more source
Indigenous knowledge data management issues and co-production of knowledge in Kamchatka
Arctic ScienceThis review analyzes content from various sources, including international projects, academic research, and government-supported programs that focus on the traditional knowledge of the Indigenous peoples in Kamchatka.
Victoria N. Sharakhmatova
doaj +1 more source
, 2021 Digital Scholarship Initiatives, an extension of the mission of the Walker Library as an active partner in the scholarly communication process, supports the educational mission of the university by providing access to information.
Digital Scholarship Initiatives
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Advanced Science, EarlyView.This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang +16 more
wiley +1 more source
, 2016 This project was carried out in the context of the HEA ‘Staff Transitions’ stream of work, with a view to investigating the extent to which activities undertaken under the banner of the Scholarship of Teaching and Learning (SoTL) might inform a sector ...
Fanghanel, Joelle +3 more
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O‐GlcNAcylated TAP1 Impairs Antigen Presentation and Promotes Immune Evasion in Bladder Cancer
Advanced Science, EarlyView.This article unveils a critical mechanism of immune evasion in bladder cancer, which the O‐GlcNAc modification of TAP1 disrupts antigen presentation. This modification triggers HLA‐A degradation, shielding tumor cells from CD8+ T cell attack. The findings highlight targeting this pathway as a promising therapeutic avenue to sensitize tumors to ...
Jinpeng Wu +10 more
wiley +1 more source
2013 Symposium on Scholarship of Teaching and Learning: Conference Program
, 2013 4th annual Symposium on Scholarship of Teaching and Learning Banff, Alberta, Canada November 7 - 9, 2013 This gathering of teacher/scholars is a practitioners conference dedicated to developing individual and collaborative teaching and learning ...
Institute for Scholarship of Teaching and Learning
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T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
, 2015 The increasing emphasis on embedding work-integrated learning (WIL) in the higher education curriculum has impacted on teaching and learning approaches. While the benefits of incorporating experiential learning in the student experience are recognized by
Moore, Keri +4 more
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