Results 51 to 60 of about 477,509 (235)
Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis. [PDF]
Cytochrome P450 (CYP) monooxygenases epoxidize the omega-3 polyunsaturated fatty acid (PUFA) docosahexaenoic acid into novel epoxydocosapentaenoic acids (EDPs) that have multiple biological actions.
Hammock, Bruce D+5 more
core +3 more sources
Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis
Collagen-I fibrillogenesis is crucial to health and development, where dysregulation is a hallmark of fibroproliferative diseases. Here, we show that collagen-I fibril assembly required a functional endocytic system that recycles collagen-I to assemble ...
Joan Chang+19 more
doaj +1 more source
Telangiectatic Macules Spreading During More Than 30 Years: A Quiz
is missing (Quiz)
Italo Francesco Aromolo+4 more
doaj +1 more source
Genotype-phenotype correlation study in 364 osteogenesis imperfecta Italian patients [PDF]
Osteogenesis imperfecta (OI) is a rare genetic disorder of the connective tissue and 90% of cases are due to dominant mutations in COL1A1 and COL1A2 genes.
Boarini, Manila+11 more
core +1 more source
Joint diseases are prevalent in orthopedic, rheumatological, and sports medicine fields, significantly impacting patients' quality of life. Collagen, a primary component of connective tissues, has emerged as a therapeutic agent for these conditions ...
Maria Wojcieszek+7 more
doaj +1 more source
Blue sclera and osteogenesis imperfecta - A rare association
The sclera is a dense poorly vascularized connective tissue structure composed of Types I, III, IV, V, VI, and VIII collagen. The characteristic blue sclera is caused by thinness and transparency of the collagen fibers of the sclera that allow ...
Sujit Das, Kavita Bhatnagar
doaj +1 more source
Elevated expression of type VII collagen in the skin of patients with systemic sclerosis. Regulation by transforming growth factor-beta. [PDF]
A hallmark of systemic sclerosis (SSc) is the development of tissue fibrosis. Excessive production of several connective tissue components normally present in the dermis, including type I, III, V, and VI collagens as well as fibronectin and proteoglycans,
Christiano, Angela M.+5 more
core +3 more sources
A study of Pulmonary Manifestations in Collagen Vascular Diseases
Introduction: Collagen vascular diseases are group of diseases with specific characteristics. Pulmonary manifestations are com- monly present in collagen Vascular Diseases.
Parul Vadgama, Pankaj Garg
doaj
Um caso de dermatose perfurante adquirida
Apresenta-se um caso de dermatose perfurante adquirida, frequentemente associada com diabetes mellitus e insuficiência renal crónica. Trata-se de uma senhora de 61 anos, diabética, com um quadro de pápulas e nódulos umbilicados, com centro quera-tósico e
Ana Dantas, Gonçalo Melo
doaj +1 more source
Endothelial cell (EC) transplantation via injectable collagen hydrogel has received much attention as a potential treatment for various vascular diseases.
Dake Hao+17 more
doaj +1 more source