Collagen type II is downregulated in the degenerative nucleus pulposus and contributes to the degeneration and apoptosis of human nucleus pulposus cells. [PDF]
Lian C +8 more
europepmc +1 more source
This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang +10 more
wiley +1 more source
Cell Adhesion by Design: Engineering Tissue Culture Scaffolds With Adhesion Cues
ABSTRACT In scaffold‐based tissue engineering, the matrix should provide adequate adhesion cues for cell attachment, spreading, and function. Given the multitude of adhesion receptors and the diversity of scaffolds, there are many approaches to render scaffolds adhesive, even though they are not all equivalent.
Dalia Dranseike +3 more
wiley +1 more source
Interface‐Engineered Binary Framework Composites: Advancing Porous Materials for Precision Medicine
Binary framework composites integrate two complementary porous architectures into a unified platform, enabling multifunctional design, enhanced structural tunability, and improved physicochemical performance. By combining high surface area, ordered porosity, interfacial synergy, and versatile functionalization, these hybrid materials offer new ...
Navid Rabiee +3 more
wiley +1 more source
Silencing of Wnt5a prevents interleukin-1β-induced collagen type II degradation in rat chondrocytes. [PDF]
Shi S, Man Z, Li W, Sun S, Zhang W.
europepmc +1 more source
Femtosecond‐Laser Mould Texturing Enables Tunable Biointerfaces in COC Microfluidics
Femtosecond‐laser texturing of injection‐mould inserts enables scalable engineering of biointerfaces in cyclic olefin copolymer microfluidics. Replicated micro‐ and nano‐topographies modulate surface roughness and wettability, leading to texture‐dependent protein adsorption and cell adhesion without chemical post‐processing.
Irene Varela‐Leniz +9 more
wiley +1 more source
A 3D‐Printed Blister Test Platform for Quantifying Biointerface Adhesion Mechanisms
A 3D‐printed blister platform enables energy‐resolved characterization of soft hydrogel–rigid interfaces. Integrating precision pressure control with hyperelastic modeling directly quantifies adhesion energy (G) and R‐curve toughening. Results reveal that modulating hydrogel concentration and surface roughness drives a tunable transition from cohesive ...
Yoontae Kim +4 more
wiley +1 more source
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane +4 more
wiley +1 more source
Additive Manufacturing of Patient‐Specific Intracranial Aneurysm Cell Culture Models
Patient‐specific intracranial aneurysm models were fabricated using chocolate moulding, 3D printed water‐soluble cores, and direct resin 3D printing. Moulding PDMS around sacrificial cores made of chocolate or 3D printed water‐soluble resin yielded accurate, expandable, and endothelializable models that outperformed resin‐based approaches.
Chloe M. de Nys +6 more
wiley +1 more source
Effect of polyacrylamide gel elasticity on collagen type II fibril assembly.
Wilcox KG +6 more
europepmc +1 more source

