Results 11 to 20 of about 916,539 (289)
Type VII collagen in Alport syndrome [PDF]
Nephrology Dialysis Transplantation, 2007 Absence or segmental distribution of the alpha5(IV) collagen chain along the epidermal basement membrane (EBM) is diagnostic of X-linked Alport syndrome (X-AS), but the typical morphologic alterations usually observed along the glomerular basement membrane (GBM) are lacking. However, several differences in protein composition exist between GBM and EBM,
GIANNAKAKIS, Konstantinos +5 more
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Type VII Collagen Expression in the Human Vitreoretinal Interface, Corpora Amylacea and Inner Retinal Layers. [PDF]
PLoS ONE, 2015 Type VII collagen, as a major component of anchoring fibrils found at basement membrane zones, is crucial in anchoring epithelial tissue layers to their underlying stroma.
Bart Wullink +4 more
doaj +3 more sources
Cylindroma Overexpresses Collagen VII, the Major Anchoring Fibril Protein [PDF]
Journal of Investigative Dermatology, 1991 The cell clusters of the human adnexal tumor, cylindroma, are surrounded by an unusual, thick, unorganized basement membrane-like zone in vivo. Ultrastructural analysis of this electron-dense zone revealed recesses that contained numerous anchoring fibrils.
Bruckner-Tuderman L +2 more
openaire +4 more sources
Characterisation of collagen-derived biomaterials [PDF]
, 2009 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University on 22 May 2009.One of the main problems in healthcare is the loss or failure of organs or tissues resulting from diseases, post-surgery complications ...
de Castro Bras, Lisandra
core +7 more sources
Dystrophic epidermolysis bullosa: genotype-phenotype correlations [PDF]
Vestnik Dermatologii i Venerologii, 2023 Dystrophic epidermolysis bullosa is caused by mutations in the COL7A1 gene. The disease characterized by clinical heterogeneity. To date, scientific findings allow to evaluate correlations between the severity of clinical manifestations and genetic ...
Alexey A. Kubanov +2 more
doaj +1 more source
Acta Dermato-Venereologica, 2021 Epidermolysis bullosa acquisita is a pemphigoid disease characterized by autoantibodies against type VII collagen. This study compared the sensitivity and specificity of 6 diagnostic assays: type VII collagen non-collagenous domains enzyme-linked ...
Maike M. Holtsche +9 more
doaj +1 more source
A novel deletion and two recurrent substitutions on type VII collagen gene in seven Iranian patients with epidermolysis bullosa [PDF]
Iranian Journal of Basic Medical Sciences, 2016 Objective(s): Epidermolysis bullosa is one of the most important series of mechano-bullous heritable skin disorders which is categorized into four major types according to the layer that bullae forms within basement membrane zone.
Armita Kakavand Hamidi +3 more
doaj +1 more source
Frontiers in Immunology, 2022 Collagen VII is the main constituent of the anchoring fibrils, important adhesive structures that attach the epidermis to the dermal extracellular matrix.
Franziska Schauer +9 more
doaj +1 more source
CRISPR/Cas9-Mediated Generation of COL7A1-Deficient Keratinocyte Model of Recessive Dystrophic Epidermolysis Bullosa [PDF]
Cell Journal, 2023 Objective: Recessive dystrophic epidermolysis bullosa (RDEB) is a genetic skin fragility and ultimately lethal blisteringdisease caused by mutations in the COL7A1 gene which is responsible for coding type VII collagen.
Farzad Alipour +5 more
doaj +1 more source
The time-dependent rearrangement of the epithelial basement membrane in human skin wounds [PDF]
, 1992 In 62 human skin wounds (surgical wounds, stab wounds and lacerations after surgical treatment) we analyzed the immunohistochemical localization of collagen IV in the epithelial basement membrane.
Penning, R. +6 more
core +1 more source