Results 21 to 30 of about 916,539 (289)

Immunohistochemical localization of collagen types I and VI in human skin wounds [PDF]

, 1996
A total of 74 human skin wounds were investigated and collagen types I and VI were localized in the wound area by immunohistochemistry. Collagen type I appeared in the form of ramifying string-like structures after approximately 5–6 days, but positive ...
Penning, R., Eisenmenger, Wolfgang, Nerlich, A., Tübel, J., Wilske, J., Betz, P.   +5 more
core   +1 more source

Diagnostic potential of Type VII Collagen during oral carcinogenesis [PDF]

Journal of Applied Oral Science, 2023
Type VII collagen (Col7) is a major component of anchoring fibrils. Col7 plays a role in tumor development and aggressiveness of cutaneous squamous cell carcinoma of recessive dystrophic epidermolysis bullosa.
Sopee POOMSAWAT, Abdulshukor KARIYA, Thirayost NIMMANON, Theerachai KOSANWAT, Rachai JUENGSOMJIT, SANGUANSIN Sirima   +5 more
doaj   +1 more source

Mechanical properties of collagen fibrils [PDF]

, 2007
The formation of collagen fibers from staggered subfibrils still lacks a universally accepted model. Determining the mechanical properties of single collagen fibrils ( diameter 50 - 200 nm) provides new insights into collagen structure. In this work, the
Bozec, L, Horton, M A, Wenger, M P E, Wenger, MPE, Horton, MA, Mesquida, P   +5 more
core   +1 more source

Increase in types IV and VI collagen in cherry haemangiomas [PDF]

, 1992
The capillaries in cherry haemangiomas show perivascular hyalinized sheaths. In order to clarify the nature of this sheath material, the extracellular matrix of cherry haemangiomas from 20 normal volunteers (age range 30-64 years) was investigated using ...
Tamm, Ernst R., Jungkunz, W., Marsch, W. C., Lütjen-Drecoll, E.   +3 more
core   +1 more source

Medical cell technologies for treatment of patients suffering from recessive dystrophic epidermolysis bullosa. Method of intracutaneous administration of fibroblasts

Vestnik Dermatologii i Venerologii, 2017
Recessive dystrophic epidermolysis bullosa (RDEB) is a severe inherited disease developing due to genetic abnormalities in the synthesis of Type VII collagen by fibroblasts.
V. I. Albanova, A. E. Karamova, V. V. Chikin, A. A. Mineyeva   +3 more
doaj   +1 more source

Epidermolysis bullosa acquisita treated with ustekinumab: A case report

SAGE Open Medical Case Reports, 2022
Epidermolysis bullosa acquisita is a rare autoimmune disease involving cutaneous blistering and scarring associated with collagen VII autoantibodies.
Connor Prosty, Justina Guirguis, May Chergui, Waqqas Afif, Elena Netchiporouk   +4 more
doaj   +1 more source

Cytosine Deaminase Base Editing to Restore COL7A1 in Dystrophic Epidermolysis Bullosa Human: Murine Skin Model

JID Innovations, 2023
Recessive dystrophic epidermolysis bullosa is a debilitating blistering skin disorder caused by loss-of-function mutations in COL7A1, which encodes type VII collagen, the main component of anchoring fibrils at the dermal−epidermal junction.
Gaetano Naso, Soragia Athina Gkazi, Christos Georgiadis, Vignesh Jayarajan, Joanna Jacków, Roland Fleck, Leanne Allison, Olumide Kayode Ogunbiyi, John Alexander McGrath, Dusko Ilic, Wei-Li Di, Anastasia Petrova, Waseem Qasim   +12 more
doaj   +1 more source

Effect of Low-Temperature Plasma Jet on Thermal Stability and Physical Structure of Type I Collagen [PDF]

, 2012
This work is devoted to the characterization of type I collagen treated by a low-temperature plasma jet generated in ambient air to determine whether the resulting fibrous material is structurally preserved or reinforced.
Yousfi, Mohammed, Gardou, Jean-Pierre, Merbahi, Nofel, Delaunay, Florian, Lacabanne, Colette, Samouillan, Valérie, Dandurand, Jany   +6 more
core   +1 more source

Anti-Type VII Collagen Antibodies Are Identified in a Subpopulation of Bullous Pemphigoid Patients With Relapse

Frontiers in Immunology, 2018
Bullous pemphigoid (BP) is an autoimmune bullous skin disease characterized by anti-BP180 and anti-BP230 autoantibodies (AAbs). Mucous membrane involvement is an uncommon clinical feature of BP which may evoke epidermolysis bullosa acquisita, another ...
Delphine Giusti, Delphine Giusti, Grégory Gatouillat, Grégory Gatouillat, Sébastien Le Jan, Julie Plée, Julie Plée, Philippe Bernard, Philippe Bernard, Frank Antonicelli, Frank Antonicelli, Bach-Nga Pham, Bach-Nga Pham   +12 more
doaj   +1 more source

Antisense Oligonucleotide-mediated Exon Skipping as a Systemic Therapeutic Approach for Recessive Dystrophic Epidermolysis Bullosa

Molecular Therapy: Nucleic Acids, 2016
The “generalized severe” form of recessive dystrophic epidermolysis bullosa (RDEB-gen sev) is caused by bi-allelic null mutations in COL7A1, encoding type VII collagen. The absence of type VII collagen leads to blistering of the skin and mucous membranes
Jeroen Bremer, Olivier Bornert, Alexander Nyström, Antoni Gostynski, Marcel F Jonkman, Annemieke Aartsma-Rus, Peter C van den Akker, Anna MG Pasmooij   +7 more
doaj   +1 more source