Results 1 to 10 of about 300,263 (378)

The addition of collagenase to BromAc® for the management of inoperable pseudomyxoma peritonei – in vitro results [PDF]

Pleura and Peritoneum
Pseudomyxoma peritonei (PMP) is a rare peritoneal malignancy. BromAc® is a novel therapeutic agent which has been developed to dissolve and facilitate the drainage of mucin as a palliative treatment for PMP; however, its effect is significantly reduced ...
Vici Carissa, Eapen Mathew, Narang Pooja, Morris David L.   +3 more
doaj   +2 more sources

Collagenase clostridium histolyticum for the treatment of Dupuytren’s contracture: systematic review and economic evaluation

Health Technology Assessment, 2015
Background: Dupuytren’s disease is a slowly progressive condition of the hand, characterised by the formation of nodules in the palm that gradually develop into fibrotic cords. Contracture of the cords produces deformities of the fingers.
Miriam Brazzelli, Moira Cruickshank, Emma Tassie, Paul McNamee, Clare Robertson, Andrew Elders, Cynthia Fraser, Rodolfo Hernandez, David Lawrie, Craig Ramsay   +9 more
doaj   +2 more sources

Investigation of antioxidant, anti collagenase, anti-elastase, and anti-hyaluronidase activities of Solanum trilobatum L. for pharmaceutical development [PDF]

Journal of Advanced Pharmaceutical Technology & Research
The health and beauty sectors are significant drivers for the continuous growth of related product markets. Solanum trilobatum L. (S. trilobatum), locally known as Ma Waeng Krue, is a popular medicinal plant utilized in primary health care in Thailand ...
Chanai Noysang, Monsicha Khuanekkaphan, Teerarat Pummarin, Wiphupat Buranasukhon, Em-on Chaiprateep   +4 more
doaj   +2 more sources

Combination of violet light irradiation and collagenase treatments in a rabbit model of keratoconus

Frontiers in Medicine, 2023
PurposeWe evaluated the use of collagenase treatment to generate a rabbit model of keratoconus and the impact of violet light (VL) irradiation on the disease model in six Japanese White rabbits.MethodsAfter epithelial debridement, the collagenase group ...
Hidenaga Kobashi, Hidenaga Kobashi, Takashi Yano, Kazuo Tsubota, Kazuo Tsubota   +4 more
doaj   +1 more source

Protein Truncating Variants of colA in Clostridium perfringens Type G Strains

Frontiers in Cellular and Infection Microbiology, 2021
Extracellular matrix (ECM) degrading enzymes produced by Clostridium perfringens may play an important role during the initial phases of avian necrotic enteritis by facilitating toxin entry in the intestinal mucosa and destruction of the tissue.
Lore Van Damme, Natasja Cox, Chana Callens, Michelle Dargatz, Monika Flügel, Sarah Hark, Frank Thiemann, Stefan Pelzer, Freddy Haesebrouck, Richard Ducatelle, Filip Van Immerseel, Evy Goossens   +11 more
doaj   +1 more source

EXTRACTION OF COLLAGENOLYTIC ENZYME FROM FISH VISCERA BY PHASE PARTITIONING (PEG/CITRATE) AND ITS POTENTIAL FOR INDUSTRIAL APPLICATION

Boletim do Instituto de Pesca, 2021
Internal viscera fish are potential sources of protein biomolecules of biopharmaceutical interest. However, this residue is frequently discarded inappropriately. The possibility to obtain by products of higher added value is a reality.
Jessica Costa SILVA, Luiz Henrique Svintiskas LINO, Márcia Nieves CARNEIRO DA CUNHA, Juanize Matias da Silva BATISTA, Vagne Melo OLIVEIRA, Ana Lúcia Figueiredo PORTO   +5 more
doaj   +1 more source

Influence of ethylene oxide gas treatment on the in vitro degradation behavior of dermal sheep collagen [PDF]

, 1995
The influence of ethylene oxide gas treatment on the in vitro degradation behavior of noncrosslinked, glutaraldehyde crosslinked or hexamethylene diisocyanate crosslinked dermal sheep collagen (DSC) using bacterial collagenase is described.
Dijkstra, P.J., Feijen, J., Luyn, M.J.A. van, Nieuwenhuis, P., Olde Damink, L.H.H., Wachem, P.B. van   +5 more
core   +9 more sources

Isolation of rat hepatocytes for pharmacological studies on metabotropic glutamate receptor (mGluR) subtype 5: a comparison between collagenase I versus collagenase IV

European Journal of Histochemistry, 2020
Isolated hepatocytes can be obtained from the liver by collagenase infusion, a procedure that could affect cell isolation as well as the integrity of membrane receptors.
Clarissa Berardo, Andrea Ferrigno, Veronica Siciliano, Plinio Richelmi, Mariapia Vairetti, Laura Giuseppina Di Pasqua   +5 more
doaj   +1 more source

Skin Anti-Aging Potential of Ipomoea pes-caprae Ethanolic Extracts on Promoting Cell Proliferation and Collagen Production in Human Fibroblasts (CCD-986sk Cells)

Pharmaceuticals, 2022
Collagen loss in the skin dermis is a major cause of age-related changes to the skin. Natural phytochemical substances are desirable for the prevention of skin aging and the formation of wrinkles.
Tasanee Panichakul, Saranyoo Ponnikorn, Wipa Tupchiangmai, Woraphot Haritakun, Kitima Srisanga   +4 more
doaj   +1 more source

Protease from Mucor subtilissimus UCP 1262: Evaluation of several specific protease activities and purification of a fibrinolytic enzyme [PDF]

Anais da Academia Brasileira de Ciências, 2020
The industrial demand for proteolytic enzymes is stimulating the search for new enzyme sources. Fungal enzymes are preferred over bacterial enzymes, and more effective and easier to extract.
THIAGO P. NASCIMENTO, AMANDA EMMANUELLE S. CONNIFF, JOSÉ ARION S. MOURA, JUANIZE MATIAS S. BATISTA, ROMERO MARCOS P.B. COSTA, CAMILA S. PORTO, GALBA MARIA C. TAKAKI, TATIANA S. PORTO, ANA LÚCIA F. PORTO   +8 more
doaj   +2 more sources