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Human Granulocyte Collagenase

Science, 1968
A collagenase, operative at neutral and alkaline p H, has been extracted from the granule fraction of human granulocytic leukocytes. It digests reconstituted collagen fibrils and reduces the viscosity of collagen solutions.
G S, Lazarus   +3 more
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Collagenases in cancer

Biochimie, 2005
Three mammalian collagenases (MMP-1, MMP-8, and MMP-13) belong to family of matrix metalloproteinases and are the principal secreted endopeptidases capable of cleaving collagenous extracellular matrix. In addition to fibrillar collagens, collagenases can cleave several other matrix and non-matrix proteins including growth factors, and this way regulate
Risto, Ala-aho, Veli-Matti, Kähäri
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Collagen-Bound Collagenase

Connective Tissue Research, 1980
The presence of collagenase bound to collagen extracted and purified from several animal and human sources by a standard procedure has been confirmed by different methods. Polyacrylamide (10%) gel electrophoresis at pH 8.1 of intact or "spontaneously"degraded neutral salt soluble collagen results in the separation of two components: the upper one says ...
A, Pardo   +3 more
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