Results 241 to 250 of about 300,263 (378)

Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice.

Journal of Clinical Investigation, 2001
L. A. Neuhold, L. Killar, Weiguang Zhao, M. Sung., L. Warner, J. Kulik, James Turner, William Wu, C. Billinghurst, T. Meijers, A. Poole, P. Babij, L. Degennaro   +12 more
semanticscholar   +1 more source

a micro-assay method of collagenase activity and its application in the study of collagen metabolism in pathological tissues

, 1984
永井 裕, 堀 久枝, 服部 俊治, 砂田 泰伸, 寺戸 国昭, 橋田 亮一, 宮本 和代   +6 more
openalex   +2 more sources

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Phytochemical characterization, total phenolic and flavonoid content, antioxidant capacity, enzymatic profiling, and cytotoxicity of Bidens pilosa and Croton sp. from Colombia for applications in skin health. [PDF]

PLoS One
Quintero-Rincón P, Caballero-Gallardo K, Galeano E, Flórez-Acosta O.   +3 more
europepmc   +1 more source

Collagenase unwinds triple‐helical collagen prior to peptide bond hydrolysis

EMBO Journal, 2004
L. Chung, D. Dinakarpandian, Naoto Yoshida, Janelle L. Lauer-Fields, G. Fields, R. Visse, H. Nagase   +6 more
semanticscholar   +1 more source

SELECTION OF OPTIMAL NUTRIENT MEDIUM FOR COLLAGENASE BIOSYNTHESIS BY ASSOCIATION ASPERGILLUS AWAMORI 16 AND ASPERGILLUS AWAMORI 22

, 2019
R. K. Blieva, Ж.Б. СУЛЕЙМЕНОВА, Aigerim Zhakipbekova, Aigul Kalieva, Zh. K. Saduyeva, Zh. K. Rakhmetova, А. S. Zhakipbekova, MSc in Biotechnology, Almaty, Kazakhstan; aika90aiko@mail.ru; https://orcid.org/0000-0002-7927-4738, A. K. Kalieva, Zh. K. Saduyeva, MSc in Biotechnology, Almaty, Kazakhstan; saduyeva@mail.ru; https://orcid.org/0000-0002-0227-3243, Zh. K. Rakhmetova, MSc in Biotechnology, Almaty, Kazakhstan; zhanar.rakhmet@mail.ru; https://orcid.org/0000-0003-0490-6208   +12 more
openalex   +1 more source

p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway

Advanced Science, EarlyView.
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa, Teh‐Wei Wang, Satoshi Kawakami, Shota Tanimoto, Kiyoshi Yamaguchi, Taketomo Kido, Masamichi Kimura, Tsunekazu Hishima, Yuki T. Okamura, Satotaka Omori, Takumi Iritani, Toshikaze Chiba, Takehiro Jimbo, Michio Katano, Kansuporn Kamataki, Ryoichi Yokoyama, Eigo Shimizu, Kiminori Kimura, Satoshi Yamzaki, Seiya Imoto, Yoichi Furukawa, Atsushi Miyajima, Yoshikazu Johmura, Makoto Nakanishi   +23 more
wiley   +1 more source

METTL3 inhibition alleviates neuroinflammation and apoptosis by reducing ETV4 m6A modification. [PDF]

Front Immunol
He D, Jiang X, Guo G, Ma J, Chen J, Zhang Y, Zhuang J, Xie P, Zhang Z.   +8 more
europepmc   +1 more source

Degradation of dermal fibrillar structures: effects of collagenase, elastase, dithioerythritol and citrate

, 1977
T Kobayasi, B Hentzer, G. Asboe‐Hansen
openalex   +2 more sources

Collagenase specificity in chondrosarcoma metastasis [PDF]

, 1999
Sean P. Scully, Kenrick Berend, Weichen Qi, John M. Harrelson   +3 more
openalex   +1 more source