Results 241 to 250 of about 188,356 (306)

[A new method for extracting adult mouse cardiac fibroblasts more efficiently and stably]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Ma X, Wang H, Ma X, Song Y, Yu J, Sun Y, Li Y, Xue L, Li X, Yang J, Wang Y.   +10 more
europepmc   +1 more source

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

Advanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu, Chao Xu, Jun Jiang, Limin He, Yike Zhou, Zhengxuan Li, Yu Li, Keying Zhang, Fa Yang, Tong Lu, Hongtao Song, Hai Zhu, Zhihao Hu, Xiaolong Zhao, Kai Gan, Hongji Li, Bo Yang, Rui Zhang, Weihong Wen, Donghui Han, Weijun Qin   +20 more
wiley   +1 more source

Lesion Site‐Targeted Microspheres Modulate Nav1.7‐Related Signaling for Osteoarthritis Treatment

Advanced Science, EarlyView.
Cartilage‐targeted carbamazepine‐loaded WYRGRL‐modified composite microspheres (CBZ/WCOM) anchor to exposed type II collagen in osteoarthritic lesions and release carbamazepine under acidic conditions. This bind‐then‐release platform modulates Nav1.7‐related sodium signaling, Na⁺/Ca²⁺ exchanger‐associated Ca2+ dynamics, and heat shock protein 70 ...
Cheng Chen, Jiaying Li, Jinjin Ma, Xiaonan Yuan, Yao Xiao, Yang Zhang, Yuan Chen, Hao Jiang, Hui He, Jie Hu, Qianglong Chen, Jinniu Zhang, Bin Li, Yun Zhou, Fengxuan Han, Yong Wang   +15 more
wiley   +1 more source

hBM-MSC-Laden 3D Bioprinted Gelatin-Alginate Hydrogels: Physicochemical Characterisation and Osteogenic Lineage Commitment. [PDF]

Gels
Garna DF, Zhang Z, Di-Silvio L.
europepmc   +1 more source

GC-MS profiling, biological activities and molecular docking of total sterol extracts from Pontederia crassipes (Lake Tana, Ethiopia). [PDF]

Sci Rep
Ben Bakrim W, Ezzariai A, Mahdi I, Karouach F, Merghoub N, Kibret M, Hafidi M, Kouisni L.   +7 more
europepmc   +1 more source

Reply to Commentary on Article: iCare Technique of Dissolving Ellanse M Nodules Using Collagenase: A Case Series and Experimental Study. [PDF]

J Cosmet Dermatol
Wu L.
europepmc   +1 more source

Comprehensive chemical, morphological, thermal, and biological characterization of Agave tequilana extract and chitosan-based dissolving microneedle arrays. [PDF]

PLoS One
Quintero-Rincón P, Caballero-Gallardo K, Flórez-Acosta O.   +2 more
europepmc   +1 more source

Clarifying the critical differences between the enzymatic stromal vascular fraction and the mechanically derived stromal vascular tissue or nanofat for spinal cord injury applications. [PDF]

Stem Cell Res Ther
Nonnarath C, Serratrice N.
europepmc   +1 more source

Multiscale photoacoustic imaging of stroke in preclinical models and future directions toward clinical translation [Invited]. [PDF]

Biomed Opt Express
Kim J, Kweon JY, Jeon H, Lee K, Kim J, Ahn YJ, Kim C.   +6 more
europepmc   +1 more source