Results 201 to 210 of about 20,337 (280)

Thermostable Bacterial Collagenolytic Proteases: A Review. [PDF]

J Microbiol Biotechnol
Zhang K, Han Y.
europepmc   +1 more source

Promotion of DFU Wound Healing via BRG1–COL16A1 Axis in Fibroblasts

Advanced Science, EarlyView.
In normal wound healing, transcription factor BRG1 is upregulated and binds the COL16A1 promoter to enhance its expression, promoting fibroblast proliferation, migration, contraction, extracellular matrix deposition, and granulation tissue formation, thus accelerating wound closure.
Penghui Wang, Jiaming Sun, Ying Wang, Bichen Ren, Yuxin Liu, Yunhan Liu, Liang Chen, Lu Yu, Tao Dai, Li Yu, Zhihui Dong   +10 more
wiley   +1 more source

Validation of a rapid collagenase activity detection technique based on fluorescent quenched gelatin with synovial fluid samples. [PDF]

BMC Biotechnol
de la Fuente M, Delgado D, Beitia M, Barreda-Gómez G, Acera A, Sanchez M, Vecino E.   +6 more
europepmc   +1 more source

Hypofractionated Radiotherapy Induces ISG15+MHC‐I+ Neutrophils to Augment Anti‐Tumor Immunity and Prime Immune Checkpoint Blockade Responses in Rectal Cancer

Advanced Science, EarlyView.
ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu, Haihong Wang, Mingjie Li, Qian Xu, Linlin Zheng, Chaoqun Han, Zhenwei Zou, Jinghua Ren, Xiaorong Dong, Peng Zhang, Kaixiong Tao, Zhenyu Lin, Tao Zhang   +12 more
wiley   +1 more source

Macrophage Paracrine Signalling Differentially Affects Fibroblast-Induced Collagenous Tissue Remodelling. [PDF]

Tissue Eng Regen Med
Brouwer HFM, Mansoor AK, Dekker S, Bouten CVC, Ito K, Foolen J, Smits AIPM.   +6 more
europepmc   +1 more source

Metalloproteinase and inhibitor expression profiling of resorbing cartilage reveals pro-collagenase activation as a critical step for collagenolysis [PDF]

core   +1 more source

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source

Research advances of matrix metalloproteinases family in uveal melanoma. [PDF]

Eur J Med Res
Chen Y, Yan Y, Wei W.
europepmc   +1 more source

Periodontitis Induces B Cell‐Macrophage Crosstalk to Exacerbate Glucose Dysregulation in Obesity

Advanced Science, EarlyView.
In obesity, periodontitis exacerbates hyperglycemia and exhibits a liver‐centric preference for glucose regulation. This occurs through a periodontitis‐driven circuit between pathogenic B cells and hepatic macrophages. Their reciprocal expansion, orchestrated by the NLRP3/IL‐18 signaling pathway, amplifies metabolic inflammation and disrupts glucose ...
Wen‐Zhen Lin, Lu‐Jun Zhou, Hui‐Lin Ye, Ting Liu, Bo‐Yan Chen, Xue‐Bing Bai, Jun Zhang, Lan Bai, Lin‐Juan Du, Yuan Liu, Yong‐Li Wang, Hong Zhu, Yu‐Lin Li, Shuo Xu, Xiao‐Qian Meng, Guo‐Cai Tian, Yan Liu, Wu‐Chang Zhang, Ya‐Qin Zhu, Sheng‐Zhong Duan   +19 more
wiley   +1 more source

Effects of Collagenase Preconditioning on Partially Incised Rat Tendon Treated with Light-Emitting Diodes and Platelet-Rich Plasma. [PDF]

Biomedicines
Alzyoud JAM, Al-Shudiefat AAS, Ali HA, Omoush SA, Shuqair DAO.   +4 more
europepmc   +1 more source