Results 61 to 70 of about 495,517 (303)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
, 2016 Identifying the most influential spreaders that maximize information flow is a central question in network theory. Recently, a scalable method called "Collective Influence (CI)" has been put forward through collective influence maximization.
Makse, Hernán A. +3 more
core +2 more sources
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
An Emergentist Account of Collective Cognition in Collaborative Problem Solving [PDF]
, 2006 As a first step toward an emergentist theory of collective cognition in collaborative problem solving, we present a proto-theoretical account of how one might conceive and model the intersubjective processes that organize collective cognition into one or
Black, John +3 more
core +1 more source
The existence of solutions for -Laplacian boundary value problems at resonance on the half-line [PDF]
, 2015 The concept of collective efficacy, defined as the combination of mutual trust and willingness to act for the common good, has received widespread attention in the field of criminology.
Weihua Jiang +19 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Systematic Social Observation of Public Spaces: A New Look at Disorder in Urban Neighborhoods [PDF]
, 1999 This article assesses the sources and consequences of public disorder. Based on the videotaping and systematic rating of more than 23,000 street segments in Chicago, highly reliable scales of social and physical disorder for 196 neighborhoods are ...
Raudenbush, Stephen W., Sampson, Robert
core +3 more sources
‘There is no choice apart from antibiotics…’: qualitative analysis of views on urinary infections in pregnancy and antimicrobial resistance [PDF]
, 2020 Background: Antimicrobial resistance (AMR) is a health risk as it can lead to life-threatening infections. There has been a rise in resistant urinary tract infections (UTIs) which is the most common infection in pregnancy.
Bandura A +8 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Typology and Efficacy of Framework Agreements Negotiated Between the European Commission and the Professional and Union Organizations Representing its Staff [PDF]
, 2015 On the basis that the European Commission has the legal condition of employer of the staff (civil servants and employees) serving it, this work analyzes the collective agreements (called framework agreements ) negotiated between the European Commission ...
Martínez Girón, Jesus
core +1 more source