Results 61 to 70 of about 2,598,009 (293)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Study of collective efficacy in award winning schools in Illinois serving racially diverse elementary students [PDF]

, 2012
This study examined the collective teacher efficacy in selected elementary schools, specifically exploring the extent to which those schools demonstrate collective efficacy, the nature of collective efficacy in those schools, and the underlying belief ...
Bieneman, Paula
core  

Moved by Social Justice: The Role of Kama Muta in Collective Action Toward Racial Equality

Frontiers in Psychology, 2022
Participation in collective action is known to be driven by two appraisals of a social situation: Beliefs that the situation is unfair (injustice appraisal) and beliefs that a group can change the situation (collective efficacy appraisal). Anger has been
Diana M. Lizarazo Pereira, Diana M. Lizarazo Pereira, Thomas W. Schubert, Thomas W. Schubert, Jenny Roth   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

A ChatGPT-AIPSS approach for SDGs: Classroom engagement and collective efficacy of students with different levels of critical thinking

Educational Technology & Society
Education is an important way to achieve global Sustainable Development Goals (SDGs), while classroom engagement and collective efficacy are key factors that influence SDG learning outcomes. However, students’ in-depth thinking could be limited when they
Wei Li, Jia-Wei Ji, Judy C. R. Tseng, Cheng-Ye Liu, Ji-Yi Huang, Hai-Ying Liu, Mo Zhou
doaj   +1 more source

Has the COVID-19 pandemic strengthened confidence in managing the climate crisis? Transfer of efficacy beliefs after experiencing lockdowns in Switzerland and Austria

Frontiers in Psychology, 2022
In the spring of 2020, countries introduced lockdowns as radical measures to deal with the first wave of the COVID-19 pandemic, which led to strong disruptions of people's everyday lives.
Stephanie Moser, Sebastian Seebauer
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A Longitudinal Examination of Collective Efficacy Dispersion Patterns in Sport Teams

, 2020
Collective efficacy is the belief in a team’s ability to perform a task. Team members hold individual collective efficacy beliefs, which likely causes differing efficacy beliefs (dispersion) among teammates.
Swinimer, Jamie
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source