Results 71 to 80 of about 2,598,009 (293)

Violence in urban neighborhoods: a longitudinal study of collective efficacy and violent crime [PDF]

open access: yes, 2016
Cross-sectional studies consistently find that neighborhoods with higher levels of collective efficacy experience fewer social problems. Particularly robust is the relationship between collective efficacy and violent crime, which holds regardless of the ...
Hipp, John R   +2 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Relationship between Socioeconomic Status and Pro-Environmental Behavior: The Role of Efficacy Beliefs

open access: yesSocial Sciences
Efficacy beliefs are important determinants of human behavior. In the context of social cognitive theory, the perception of collective efficacy is closely related to the individual perception of self-efficacy, which is influenced by socio-structural ...
Ivana Vrselja   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

The experience of collective participation : shared identity, relatedness and emotionality [PDF]

open access: yes, 2015
This research was supported by an ESRC Postgraduate Studentship (PTA-030-2006-00100) awarded to the first author.This paper presents three studies that explore the experience of participating in crowd events.
Neville, Fergus Gilmour   +1 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Collective Teacher Efficacy [PDF]

open access: yes, 2022
This professional learning module (PLM) was designed for those in leadership roles in educational organizations who desire to examine the effect of collective teacher efficacy for school improvement purposes.
McEntyre, Annie   +3 more
core  

Message Persuasion in the Pandemic: U.S. and Chinese Respondents’ Reactions to Mediating Mechanisms of Efficacy

open access: yesInternational Journal of Communication, 2022
In the context of the COVID-19 pandemic, this study derives from construal level theory and integrates self-construal, temporal framing, and narrative strategies to test the interactions between these variables.
He Gong, Miaohong Huang, Xiyuan Liu
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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