Results 71 to 80 of about 90,388 (256)

Generation X School Leaders as Agents of Care: Leader and Teacher Perspectives from Toronto, New York City and London

open access: yesSocieties, 2016
This paper draws on evidence from our three-year Economic and Social Research Council (ESRC)-funded research study of the lives, careers, experiences and aspirations of Generation X (under 40 years of age) principals and vice-principals in London, New ...
Karen Edge   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Women’s Rights and Gender Equality in Turkey| Voices Against Misogyny in Turkey: The Case of a Successful Online Collective Action Against a Sexist Commercial

open access: yesInternational Journal of Communication, 2020
This contribution examines a case of collective action in Turkey against a sexist advertisement. Protests unfolded exclusively through social media and resulted in more than 20,000 protestors signing a petition against the ad.
Özden Melis Uluğ   +2 more
doaj  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Conservation Behavior in the Agricultural Societies of Java

open access: yesJurnal Psikologi, 2019
This research aimed to gain a deeper understanding of the conservation behavior in the context of the Java community. A deep exploration was conducted on the ecological value model, dynamics of ecological value activation, social attachment bias and ...
R. Pasifikus Christa Wijaya   +1 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Design and validation of a community resilience scale in contexts of adversity

open access: yesFrontiers in Public Health
BackgroundCommunity Resilience has drawn growing interest over recent decades. It is now a key variable in social research and in studies of stress and coping.
Carolina Alzugaray   +5 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Impact of Professional Learning Addressing Bandura’s Efficacy Sources on Collective Teacher Efficacy

open access: yesInternational Dialogues on Education: Past and Present
Despite broad interest in fostering high levels of collective teacher efficacy, inquiries into the intentional development of collective teacher efficacy through professional learning are scarce in the literature.
Stephanie Thomas
doaj  

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