Results 131 to 140 of about 19,399 (253)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Evaluation of the implementation of the Critical Care Asia and Africa Intensive Care Unit registry in Ethiopia. [PDF]

World J Crit Care Med
Laytin AD, Zewdie A, Sultan M, Brandt AJ, Olani AB, Werkeshe G, Berenholtz SM, Checkley W, Hansoti B.   +8 more
europepmc   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Evaluating the implementation of the vignettes-based injury care process assessment tool in low- and middle-income countries settings. [PDF]

BMC Health Serv Res
Whitaker J, Ghalichi L, Amberbir A, Ignatowicz A, MacQuene T, Berhe DF, Wajidali Z, Sithole D, Agbeko AE, Twizeyimana E, Munyura NO, Rahim KA, Gudugbe S, Alhassan PDA, Navsaria P, D'Ambruoso L, Razzak J, Chu K, Davies J.   +18 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Decolonial science in the Amazon demands active and equitable seats at the table. [PDF]

NPJ Biodivers
Penha D.
europepmc   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Experimental evaluation of dermal lymphatics in preservation of lymphatic function. [PDF]

Breast Cancer Res
Hulsman L, Mohan G, Sidhu AS, Ahmed S, Sullivan SJ, Subi-Kasozi CA, Mahariq AR, Jorge MD, Sinha M, Hassanein AH.   +9 more
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The Thoracic Lymphatic Vasculature: Interorgan Strategies to Achieve an Optimal Tissue Function. [PDF]

Compr Physiol
Negrini D, Solari E, Marcozzi C, Moriondo A.   +3 more
europepmc   +1 more source